"Substrate Specificity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A characteristic feature of enzyme activity in relation to the kind of substrate on which the enzyme or catalytic molecule reacts.
| Descriptor ID |
D013379
|
| MeSH Number(s) |
G02.111.835
|
| Concept/Terms |
Substrate Specificity- Substrate Specificity
- Specificities, Substrate
- Specificity, Substrate
- Substrate Specificities
|
Below are MeSH descriptors whose meaning is more general than "Substrate Specificity".
Below are MeSH descriptors whose meaning is more specific than "Substrate Specificity".
This graph shows the total number of publications written about "Substrate Specificity" by people in this website by year, and whether "Substrate Specificity" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 6 | 6 |
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 7 | 7 |
| 1999 | 0 | 7 | 7 |
| 2000 | 0 | 7 | 7 |
| 2001 | 1 | 11 | 12 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 8 | 8 |
| 2004 | 0 | 16 | 16 |
| 2005 | 0 | 11 | 11 |
| 2006 | 0 | 6 | 6 |
| 2007 | 0 | 14 | 14 |
| 2008 | 0 | 10 | 10 |
| 2009 | 0 | 9 | 9 |
| 2010 | 0 | 17 | 17 |
| 2011 | 0 | 12 | 12 |
| 2012 | 0 | 10 | 10 |
| 2013 | 0 | 12 | 12 |
| 2014 | 0 | 6 | 6 |
| 2015 | 0 | 10 | 10 |
| 2016 | 0 | 10 | 10 |
| 2017 | 0 | 15 | 15 |
| 2018 | 1 | 8 | 9 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 5 | 6 |
| 2021 | 0 | 5 | 5 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Substrate Specificity" by people in Profiles.
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New insights into RNA processing by the eukaryotic tRNA splicing endonuclease. J Biol Chem. 2023 09; 299(9):105138.
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Substrate-driven assembly of a translocon for multipass membrane proteins. Nature. 2022 11; 611(7934):167-172.
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Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022 04 05; 13(1):1833.
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Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response. Cell Rep. 2021 11 16; 37(7):110004.
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The mechanisms of integral membrane protein biogenesis. Nat Rev Mol Cell Biol. 2022 02; 23(2):107-124.
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Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB. Protein Sci. 2021 09; 30(9):1904-1918.
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Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors. Nat Commun. 2021 02 02; 12(1):743.
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Seesaw conformations of Npl4 in the human p97 complex and the inhibitory mechanism of a disulfiram derivative. Nat Commun. 2021 01 05; 12(1):121.
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Proofreading through spatial gradients. Elife. 2020 12 24; 9.
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Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism. Thyroid. 2021 02; 31(2):202-207.