"POU Domain Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
|POU Domain Factors
- POU Domain Factors
- Pit-Oct-Unc Proteins
- Pit Oct Unc Proteins
- POU Proteins
- Transcription Factor POU
- POU, Transcription Factor
Below are MeSH descriptors whose meaning is more general than "POU Domain Factors".
Below are MeSH descriptors whose meaning is more specific than "POU Domain Factors".
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Below are the most recent publications written about "POU Domain Factors" by people in Profiles.
Progenitor cell diversity in the developing mouse neocortex. Proc Natl Acad Sci U S A. 2021 03 09; 118(10).
Temporal transcription factors determine circuit membership by permanently altering motor neuron-to-muscle synaptic partnerships. Elife. 2020 05 11; 9.
MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer. Nat Commun. 2020 01 17; 11(1):338.
The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 12 19; 10(472).
Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 06; 77(3):472-84.
Identification of tightly regulated groups of genes during Drosophila melanogaster embryogenesis. Mol Syst Biol. 2007; 3:72.
POU/TBP cooperativity: a mechanism for enhancer action from a distance. Mol Cell. 2002 Aug; 10(2):397-407.
spiel ohne grenzen/pou2 is required for zebrafish hindbrain segmentation. Development. 2002 Apr; 129(7):1645-55.
Identification of a discrete promoter region of the human GnRH gene that is sufficient for directing neuron-specific expression: a role for POU homeodomain transcription factors. Mol Endocrinol. 2002 Mar; 16(3):435-49.