"Elongin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.
- SIII Elongation Factor
- Elongation Factor, SIII
- Transcription Factor SIII
- SIII, Transcription Factor
- Elongin Complex
- Complex, Elongin
Below are MeSH descriptors whose meaning is more general than "Elongin".
Below are MeSH descriptors whose meaning is more specific than "Elongin".
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Below are the most recent publications written about "Elongin" by people in Profiles.
The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol. 2005 Jul; 7(7):698-705.