| Item Type | Name |
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Concept
|
Age Factors
|
|
Concept
|
Antibodies, Neoplasm
|
|
Concept
|
Antigen-Presenting Cells
|
|
Concept
|
Autophagy
|
|
Concept
|
Bone Marrow Cells
|
|
Concept
|
Aging
|
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Antigens, Differentiation, T-Lymphocyte
|
|
Concept
|
Base Sequence
|
|
Concept
|
Cell Count
|
|
Concept
|
Astrocytoma
|
|
Concept
|
Attitude of Health Personnel
|
|
Concept
|
England
|
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
|
Concept
|
Cell Division
|
|
Concept
|
Carbocyanines
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
Cricetulus
|
|
Concept
|
Confidentiality
|
|
Concept
|
Dementia
|
|
Concept
|
Hospital Bed Capacity, 300 to 499
|
|
Concept
|
Dacarbazine
|
|
Concept
|
Immune System
|
|
Concept
|
Dendritic Cells
|
|
Concept
|
Drug Carriers
|
|
Concept
|
Flagellin
|
|
Concept
|
Graft Survival
|
|
Concept
|
Hybridomas
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Drosophila melanogaster
|
|
Concept
|
Drug Evaluation, Preclinical
|
|
Concept
|
Drug Therapy, Combination
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Metalloporphyrins
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Glioma
|
|
Concept
|
Glioblastoma
|
|
Concept
|
Feasibility Studies
|
|
Concept
|
Fibronectins
|
|
Concept
|
Killer Cells, Natural
|
|
Concept
|
Gold
|
|
Concept
|
T-Lymphocytes, Helper-Inducer
|
|
Concept
|
Hydrogen-Ion Concentration
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Hospital Information Systems
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Pilot Projects
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Extracellular Matrix
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Mice, Nude
|
|
Concept
|
Micelles
|
|
Concept
|
Mutation
|
|
Concept
|
Cricetinae
|
|
Concept
|
Ovalbumin
|
|
Concept
|
Lung Neoplasms
|
|
Concept
|
Sphingomyelin Phosphodiesterase
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
State Medicine
|
|
Concept
|
Humans
|
|
Concept
|
Sphingomyelins
|
|
Concept
|
Specific Pathogen-Free Organisms
|
|
Concept
|
Practice Guidelines as Topic
|
|
Concept
|
Vaccination
|
|
Concept
|
Histocompatibility Antigens Class I
|
|
Concept
|
Transduction, Genetic
|
|
Concept
|
Th1 Cells
|
|
Concept
|
Randomized Controlled Trials as Topic
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Antigens, Differentiation, Myelomonocytic
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Lymph Nodes
|
|
Concept
|
CD4-Positive T-Lymphocytes
|
|
Concept
|
Cysteine Proteinase Inhibitors
|
|
Concept
|
Immunotherapy, Adoptive
|
|
Concept
|
Lymphocytes, Tumor-Infiltrating
|
|
Concept
|
Interleukin-10
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Drug Delivery Systems
|
|
Concept
|
T-Lymphocyte Subsets
|
|
Concept
|
Sigmodontinae
|
|
Concept
|
Morphogenesis
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Interferon-alpha
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
CD8-Positive T-Lymphocytes
|
|
Concept
|
Gene Expression Regulation, Developmental
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Chemokines
|
|
Concept
|
Interleukin-12
|
|
Concept
|
Inhibitor of Apoptosis Proteins
|
|
Concept
|
Th2 Cells
|
|
Concept
|
Jurkat Cells
|
|
Concept
|
B7-H1 Antigen
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Indoleamine-Pyrrole 2,3,-Dioxygenase
|
|
Concept
|
Neovascularization, Physiologic
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
Adoptive Transfer
|
|
Concept
|
Facial Nerve Injuries
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Mice
|
|
Concept
|
Surveys and Questionnaires
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
CD11c Antigen
|
|
Concept
|
Upper Extremity
|
|
Concept
|
Molecular Targeted Therapy
|
|
Concept
|
Rats
|
|
Concept
|
Real-Time Polymerase Chain Reaction
|
|
Concept
|
CTLA-4 Antigen
|
|
Concept
|
Sex Factors
|
|
Concept
|
Interleukin-2 Receptor alpha Subunit
|
|
Concept
|
Spleen
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Electronic Health Records
|
|
Concept
|
Transfection
|
|
Concept
|
Tuberous Sclerosis
|
|
Concept
|
Patient Satisfaction
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
Minor Histocompatibility Antigens
|
|
Concept
|
Survival Rate
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
G2 Phase
|
|
Concept
|
Chemokine CCL2
|
|
Concept
|
DNA Methylation
|
|
Concept
|
Interleukin-13 Receptor alpha2 Subunit
|
|
Concept
|
Interleukin-17
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Xenograft Model Antitumor Assays
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Cell Lineage
|
|
Concept
|
Health Care Surveys
|
|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
gp100 Melanoma Antigen
|
|
Concept
|
Immune Evasion
|
|
Concept
|
Antibodies, Monoclonal, Murine-Derived
|
|
Concept
|
Tumor Microenvironment
|
|
Concept
|
Programmed Cell Death 1 Receptor
|
|
Concept
|
Kaplan-Meier Estimate
|
|
Concept
|
Chemokine CCL11
|
|
Concept
|
Neuroimaging
|
|
Concept
|
Cell Survival
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Cloning, Molecular
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Family Practice
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Kynurenic Acid
|
|
Concept
|
Longitudinal Studies
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Protoporphyrins
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
T-Lymphocytes
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Injury Severity Score
|
|
Concept
|
5'-Nucleotidase
|
|
Concept
|
Gene Expression Regulation, Neoplastic
|
|
Concept
|
Immunophenotyping
|
|
Concept
|
Sickness Impact Profile
|
|
Concept
|
Disease-Free Survival
|
|
Concept
|
Coculture Techniques
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
Microscopy, Electron, Transmission
|
|
Concept
|
Chemokine CXCL11
|
|
Concept
|
GPI-Linked Proteins
|
|
Academic Article
|
Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy.
|
|
Academic Article
|
Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice.
|
|
Academic Article
|
Recent developments on immunotherapy for brain cancer.
|
|
Academic Article
|
Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor a2.
|
|
Academic Article
|
IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
|
|
Academic Article
|
Clinical evaluation of an acellular allograft dermal matrix in full-thickness burns.
|
|
Academic Article
|
Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model.
|
|
Academic Article
|
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma.
|
|
Academic Article
|
Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma.
|
|
Academic Article
|
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
|
|
Academic Article
|
Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma.
|
|
Academic Article
|
The role of IDO in brain tumor immunotherapy.
|
|
Academic Article
|
Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.
|
|
Academic Article
|
Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin.
|
|
Academic Article
|
Advanced age negatively impacts survival in an experimental brain tumor model.
|
|
Academic Article
|
Differential actions of pituitary adenylyl cyclase-activating polypeptide and interferon gamma on Th2- and Th1-associated chemokine expression in cultured murine microglia.
|
|
Academic Article
|
Effects of facial nerve axotomy on Th2-associated and Th1-associated chemokine mRNA expression in the facial motor nucleus of wild-type and presymptomatic SOD1 mice.
|
|
Academic Article
|
Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.
|
|
Academic Article
|
Therapeutic Hypothesis Testing With Rodent Brain Tumor Models.
|
|
Academic Article
|
A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model.
|
|
Academic Article
|
Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma.
|
|
Academic Article
|
IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
|
|
Academic Article
|
IDO1 in cancer: a Gemini of immune checkpoints.
|
|
Academic Article
|
Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
|
|
Academic Article
|
Indoleamine 2,3-dioxygenase 1 and overall survival of patients diagnosed with esophageal cancer.
|
|
Academic Article
|
Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival.
|
|
Academic Article
|
Management of glioblastoma in elderly patients.
|
|
Academic Article
|
Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017).
|
|
Academic Article
|
Newly Diagnosed Glioblastoma: A Review on Clinical Management.
|
|
Academic Article
|
The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma.
|
|
Academic Article
|
The interplay among psychological distress, the immune system, and brain tumor patient outcomes.
|
|
Academic Article
|
CD73: an emerging checkpoint for cancer immunotherapy.
|
|
Academic Article
|
Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual co-stimulation of CD8 T cells and enables sMIC+ tumors respond to PD1/PD-L1 blockade therapy.
|
|
Academic Article
|
Immunotherapy Against Gliomas: is the Breakthrough Near?
|
|
Academic Article
|
Quantification of IDO1 enzyme activity in normal and malignant tissues.
|
|
Academic Article
|
A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors.
|
|
Academic Article
|
Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy.
|
|
Academic Article
|
Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
|
|
Academic Article
|
Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors.
|
|
Academic Article
|
Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
|
|
Academic Article
|
Targeting CD73 to augment cancer immunotherapy.
|
|
Academic Article
|
The Impact of Beta Blockers on Survival Outcomes in Patients With Non-small-cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
|
|
Academic Article
|
Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
|
|
Academic Article
|
NK cell-based cancer immunotherapy: from basic biology to clinical development.
|
|
Academic Article
|
Tryptophan metabolism in brain tumors - IDO and beyond.
|
|
Academic Article
|
Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation.
|
|
Academic Article
|
Fundholding in northern region: the first year.
|
|
Academic Article
|
Information management and technology in England's large acute NHS hospitals. National strategy versus local reality.
|
|
Academic Article
|
Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
|
|
Academic Article
|
Glioblastoma as an age-related neurological disorder in adults.
|
|
Academic Article
|
CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease.
|
|
Academic Article
|
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
|
|
Academic Article
|
Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved.
|
|
Academic Article
|
Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study.
|
|
Academic Article
|
Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma.
|
|
Academic Article
|
A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer.
|
|
Academic Article
|
Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
|
|
Academic Article
|
Next Steps for Immunotherapy in Glioblastoma.
|
|
Academic Article
|
Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
|
|
Concept
|
Antineoplastic Agents, Immunological
|
|
Grant
|
The role of IDO and Th17 in an experimental mouse model of glioma
|
|
Grant
|
The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
|
|
Grant
|
The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
|
|
Grant
|
Aging, immunosenescence and glioblastoma
|
|
Academic Article
|
Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
|
|
Academic Article
|
CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4.
|
|
Academic Article
|
Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
|
|
Academic Article
|
LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
|
|
Academic Article
|
Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer.
|
|
Academic Article
|
Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.
|