"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 9 | 9 |
| 1998 | 0 | 16 | 16 |
| 1999 | 0 | 19 | 19 |
| 2000 | 0 | 34 | 34 |
| 2001 | 0 | 29 | 29 |
| 2002 | 0 | 51 | 51 |
| 2003 | 0 | 32 | 32 |
| 2004 | 0 | 48 | 48 |
| 2005 | 1 | 52 | 53 |
| 2006 | 0 | 36 | 36 |
| 2007 | 0 | 45 | 45 |
| 2008 | 1 | 40 | 41 |
| 2009 | 0 | 61 | 61 |
| 2010 | 0 | 61 | 61 |
| 2011 | 1 | 62 | 63 |
| 2012 | 0 | 56 | 56 |
| 2013 | 0 | 61 | 61 |
| 2014 | 0 | 55 | 55 |
| 2015 | 1 | 59 | 60 |
| 2016 | 0 | 52 | 52 |
| 2017 | 0 | 51 | 51 |
| 2018 | 0 | 42 | 42 |
| 2019 | 0 | 29 | 29 |
| 2020 | 0 | 33 | 33 |
| 2021 | 0 | 28 | 28 |
| 2022 | 0 | 13 | 13 |
| 2023 | 0 | 9 | 9 |
| 2024 | 4 | 11 | 15 |
| 2025 | 1 | 7 | 8 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C.?elegans development. Nat Struct Mol Biol. 2025 Sep; 32(9):1683-1696.
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Structural basis for nucleolin recognition of MYC promoter G-quadruplex. Science. 2025 04 18; 388(6744):eadr1752.
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Mapping the extracellular molecular architecture of the pAg-signaling complex with a-Butyrophilin antibodies. Sci Rep. 2025 Apr 09; 15(1):12162.
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Structural basis of BAK sequestration by MCL-1 in apoptosis. Mol Cell. 2025 Apr 17; 85(8):1606-1623.e10.
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Transfer learning reveals sequence determinants of the quantitative response to transcription factor dosage. Cell Genom. 2025 Mar 12; 5(3):100780.
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Large serine integrases utilise scavenged phage proteins as directionality cofactors. Nucleic Acids Res. 2025 Jan 24; 53(3).
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Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering. Nat Commun. 2025 Jan 18; 16(1):818.
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A claudin5-binding peptide enhances the permeability of the blood-brain barrier in vitro. Sci Adv. 2025 Jan 10; 11(2):eadq2616.
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Binding mode-guided development of high-performance antibodies targeting site-specific posttranslational modifications. Proc Natl Acad Sci U S A. 2025 Jan 07; 122(1):e2411720121.
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Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function. Nat Commun. 2024 12 04; 15(1):10545.