"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 10 | 10 |
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 9 | 9 |
| 1998 | 0 | 16 | 16 |
| 1999 | 0 | 19 | 19 |
| 2000 | 0 | 33 | 33 |
| 2001 | 0 | 30 | 30 |
| 2002 | 0 | 52 | 52 |
| 2003 | 0 | 33 | 33 |
| 2004 | 0 | 48 | 48 |
| 2005 | 1 | 52 | 53 |
| 2006 | 0 | 36 | 36 |
| 2007 | 0 | 45 | 45 |
| 2008 | 1 | 39 | 40 |
| 2009 | 0 | 61 | 61 |
| 2010 | 0 | 61 | 61 |
| 2011 | 1 | 62 | 63 |
| 2012 | 0 | 56 | 56 |
| 2013 | 0 | 61 | 61 |
| 2014 | 0 | 53 | 53 |
| 2015 | 1 | 56 | 57 |
| 2016 | 0 | 51 | 51 |
| 2017 | 0 | 49 | 49 |
| 2018 | 0 | 41 | 41 |
| 2019 | 0 | 27 | 27 |
| 2020 | 0 | 32 | 32 |
| 2021 | 0 | 28 | 28 |
| 2022 | 0 | 12 | 12 |
| 2023 | 0 | 9 | 9 |
| 2024 | 2 | 6 | 8 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11.
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Structural and biophysical insights into targeting of claudin-4 by a synthetic antibody fragment. Commun Biol. 2024 Jun 17; 7(1):733.
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Epistasis facilitates functional evolution in an ancient transcription factor. Elife. 2024 May 20; 12.
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Parkinson's disease-associated mutations in a-synuclein alters its lipid-bound state. Biophys J. 2024 Jun 18; 123(12):1610-1619.
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Prediction of the essential intermolecular contacts for side-binding of VASP on F-actin. Cytoskeleton (Hoboken). 2024 Aug; 81(8):382-392.
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Guiding the HBO1 complex function through the JADE subunit. Nat Struct Mol Biol. 2024 Jul; 31(7):1039-1049.
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Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing. Nat Methods. 2024 Feb; 21(2):247-258.
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Interpreting the effect of mutations to protein binding sites from large-scale genomic screens. Methods. 2024 Feb; 222:122-132.
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Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes. Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2314920120.
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Response by Walters et al to Letter Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension". Circulation. 2023 11 28; 148(22):1825-1826.