"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 4 | 4 |
| 1994 | 0 | 10 | 10 |
| 1995 | 0 | 7 | 7 |
| 1996 | 0 | 14 | 14 |
| 1997 | 0 | 9 | 9 |
| 1998 | 0 | 16 | 16 |
| 1999 | 0 | 19 | 19 |
| 2000 | 0 | 33 | 33 |
| 2001 | 0 | 30 | 30 |
| 2002 | 0 | 51 | 51 |
| 2003 | 0 | 33 | 33 |
| 2004 | 0 | 48 | 48 |
| 2005 | 1 | 51 | 52 |
| 2006 | 0 | 36 | 36 |
| 2007 | 0 | 45 | 45 |
| 2008 | 1 | 41 | 42 |
| 2009 | 0 | 60 | 60 |
| 2010 | 0 | 62 | 62 |
| 2011 | 1 | 60 | 61 |
| 2012 | 0 | 53 | 53 |
| 2013 | 0 | 60 | 60 |
| 2014 | 0 | 53 | 53 |
| 2015 | 1 | 55 | 56 |
| 2016 | 0 | 48 | 48 |
| 2017 | 0 | 48 | 48 |
| 2018 | 0 | 39 | 39 |
| 2019 | 0 | 27 | 27 |
| 2020 | 0 | 32 | 32 |
| 2021 | 0 | 25 | 25 |
| 2022 | 0 | 12 | 12 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Computational Design and Experimental Validation of ACE2-Derived Peptides as SARS-CoV-2 Receptor Binding Domain Inhibitors. J Phys Chem B. 2022 10 20; 126(41):8129-8139.
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Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity. Sci Adv. 2022 10 07; 8(40):eabn3777.
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Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes. J Biol Chem. 2022 09; 298(9):102357.
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Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias. Sci Adv. 2022 07 15; 8(28):eabn8063.
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Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative. Proc Natl Acad Sci U S A. 2022 06 07; 119(23):e2120750119.
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Epistatic drift causes gradual decay of predictability in protein evolution. Science. 2022 05 20; 376(6595):823-830.
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HDX-MS performed on BtuB in E. coli outer membranes delineates the luminal domain's allostery and unfolding upon B12 and TonB binding. Proc Natl Acad Sci U S A. 2022 05 17; 119(20):e2119436119.
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Challenges and Advantages of Accounting for Backbone Flexibility in Prediction of Protein-Protein Complexes. J Chem Theory Comput. 2022 Mar 08; 18(3):2016-2032.
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Chaperones directly and efficiently disperse stress-triggered biomolecular condensates. Mol Cell. 2022 02 17; 82(4):741-755.e11.
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Engineered human antibodies for the opsonization and killing of Staphylococcus aureus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).