4-1BB Ligand
"4-1BB Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific for the 4-1BB RECEPTOR and may play a role in inducing the proliferation of activated peripheral blood T-LYMPHOCYTES.
Descriptor ID |
D053330
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MeSH Number(s) |
D12.644.276.374.750.065 D12.644.276.972.065 D12.776.395.192 D12.776.467.374.750.065 D12.776.467.972.065 D12.776.543.550.194 D23.529.374.750.065 D23.529.972.065
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Concept/Terms |
4-1BB Ligand- 4-1BB Ligand
- 4 1BB Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 9
- Tumor Necrosis Factor (Ligand) Superfamily, Member 9
- 4-1BBL Protein
- 4 1BBL Protein
- CD137 Ligand
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Below are MeSH descriptors whose meaning is more general than "4-1BB Ligand".
Below are MeSH descriptors whose meaning is more specific than "4-1BB Ligand".
This graph shows the total number of publications written about "4-1BB Ligand" by people in this website by year, and whether "4-1BB Ligand" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "4-1BB Ligand" by people in Profiles.
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Freeman ZT, Nirschl TR, Hovelson DH, Johnston RJ, Engelhardt JJ, Selby MJ, Kochel CM, Lan RY, Zhai J, Ghasemzadeh A, Gupta A, Skaist AM, Wheelan SJ, Jiang H, Pearson AT, Snyder LA, Korman AJ, Tomlins SA, Yegnasubramanian S, Drake CG. A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. J Clin Invest. 2020 03 02; 130(3):1405-1416.
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