 Transcription Factor AP-2
"Transcription Factor AP-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.
| Descriptor ID |
D050656
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| MeSH Number(s) |
D12.776.260.760 D12.776.930.907
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| Concept/Terms |
Transcription Factor AP-2- Transcription Factor AP-2
- AP-2, Transcription Factor
- Transcription Factor AP 2
- Transcription Factor AP2
- Enhancer-Binding Protein AP-2
- AP-2, Enhancer-Binding Protein
- Enhancer Binding Protein AP 2
- Activator Protein AP-2
- AP-2, Activator Protein
- Activator Protein AP 2
- AP-2 Enhancer Binding Protein
- AP 2 Enhancer Binding Protein
Transcription Factor AP-2 gamma Protein- Transcription Factor AP-2 gamma Protein
- Transcription Factor AP 2 gamma Protein
- Transcription Factor AP-2gamma
- AP-2gamma, Transcription Factor
- Transcription Factor AP 2gamma
- AP-2 gamma Protein
- AP 2 gamma Protein
Transcription Factor AP-2 delta Protein- Transcription Factor AP-2 delta Protein
- Transcription Factor AP 2 delta Protein
- Transcription Factor Ap-2delta
- Ap-2delta, Transcription Factor
- Transcription Factor Ap 2delta
- AP-2delta Protein
- AP 2delta Protein
Transcription Factor AP-2 epsilon Protein- Transcription Factor AP-2 epsilon Protein
- Transcription Factor AP 2 epsilon Protein
- Transcription Factor AP-2epsilon
- AP-2epsilon, Transcription Factor
- Transcription Factor AP 2epsilon
- AP-2 epsilon Protein
Transcription Factor AP-2 alpha Protein- Transcription Factor AP-2 alpha Protein
- Transcription Factor AP 2 alpha Protein
- TFAP2alpha Protein
- Transcription Factor AP-2alpha
- AP-2alpha, Transcription Factor
- Transcription Factor AP 2alpha
- AP-2 alpha Protein
- AP 2 alpha Protein
Transcription Factor AP-2 beta Protein- Transcription Factor AP-2 beta Protein
- Transcription Factor AP 2 beta Protein
- TFAP2B Protein
- Transcription Factor AP-2beta
- AP-2beta, Transcription Factor
- Transcription Factor AP 2beta
- AP-2 beta Protein
- AP 2 beta Protein
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-2".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-2".
This graph shows the total number of publications written about "Transcription Factor AP-2" by people in this website by year, and whether "Transcription Factor AP-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor AP-2" by people in Profiles.
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Raap M, Gronewold M, Christgen H, Glage S, Bentires-Alj M, Koren S, Derksen PW, Boelens M, Jonkers J, Lehmann U, Feuerhake F, Kuehnle E, Gluz O, Kates R, Nitz U, Harbeck N, Kreipe HH, Christgen M. Lobular carcinoma in situ and invasive lobular breast cancer are characterized by enhanced expression of transcription factor AP-2ß. Lab Invest. 2018 01; 98(1):117-129.
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Kin K, Nnamani MC, Lynch VJ, Michaelides E, Wagner GP. Cell-type phylogenetics and the origin of endometrial stromal cells. Cell Rep. 2015 Mar 03; 10(8):1398-409.
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Tsujimura T, Klein FA, Langenfeld K, Glaser J, Huber W, Spitz F. A discrete transition zone organizes the topological and regulatory autonomy of the adjacent tfap2c and bmp7 genes. PLoS Genet. 2015 Jan; 11(1):e1004897.
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Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Masuzaki H, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Nakamura Y, Kamatani N. Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population. J Hum Genet. 2010 Nov; 55(11):738-42.
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Leupold JH, Asangani I, Maurer GD, Lengyel E, Post S, Allgayer H. Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer. Mol Cancer Res. 2007 May; 5(5):485-96.
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Schewe DM, Biller T, Maurer G, Asangani IA, Leupold JH, Lengyel ER, Post S, Allgayer H. Combination analysis of activator protein-1 family members, Sp1 and an activator protein-2alpha-related factor binding to different regions of the urokinase receptor gene in resected colorectal cancers. Clin Cancer Res. 2005 Dec 15; 11(24 Pt 1):8538-48.
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Elde NC, Morgan G, Winey M, Sperling L, Turkewitz AP. Elucidation of clathrin-mediated endocytosis in tetrahymena reveals an evolutionarily convergent recruitment of dynamin. PLoS Genet. 2005 Nov; 1(5):e52.
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Escher R, Hagos F, Michaud J, Sveen L, Horwitz M, Olopade OI, Scott HS. No evidence for core-binding factor CBFbeta as a leukemia predisposing factor in chromosome 16q22-linked familial AML. Leukemia. 2004 Apr; 18(4):881.
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Schewe DM, Leupold JH, Boyd DD, Lengyel ER, Wang H, Gruetzner KU, Schildberg FW, Jauch KW, Allgayer H. Tumor-specific transcription factor binding to an activator protein-2/Sp1 element of the urokinase-type plasminogen activator receptor promoter in a first large series of resected gastrointestinal cancers. Clin Cancer Res. 2003 Jun; 9(6):2267-76.
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Cerda SR, Chu SS, Garcia P, Chung J, Grumet JD, Thimmapaya B, Weitzman SA. Regulation of expression of N-methylpurine DNA glycosylase in human mammary epithelial cells: role of transcription factor AP-2. Chem Res Toxicol. 1999 Nov; 12(11):1098-109.
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