Paired Box Transcription Factors
"Paired Box Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors that control EMBRYONIC DEVELOPMENT within a variety of cell lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified in DROSOPHILA segmentation genes.
| Descriptor ID |
D051761
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| MeSH Number(s) |
D12.776.260.645 D12.776.930.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paired Box Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Paired Box Transcription Factors".
This graph shows the total number of publications written about "Paired Box Transcription Factors" by people in this website by year, and whether "Paired Box Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 2 | 3 |
| 2013 | 3 | 0 | 3 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Paired Box Transcription Factors" by people in Profiles.
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A Novel Pathogenic Variant in PAX8 Leads to Familial Congenital Hypothyroidism. Thyroid. 2022 08; 32(8):1000-1002.
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Accelerating functional gene discovery in osteoarthritis. Nat Commun. 2021 01 20; 12(1):467.
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DNA-binding sequence specificity of DUX4. Skelet Muscle. 2016; 6:8.
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FOXD3 Promotes PAX3 Expression in Melanoma Cells. J Cell Biochem. 2016 Feb; 117(2):533-41.
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. J Biol Chem. 2015 Sep 04; 290(36):21901-14.
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BMP4 and FGF strongly induce differentiation of mouse ES cells into oral ectoderm. Stem Cell Res. 2015 Sep; 15(2):290-8.
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Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids. Nat Commun. 2015 Apr 22; 6:6853.
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PAX3 and ETS1 synergistically activate MET expression in melanoma cells. Oncogene. 2015 Sep 17; 34(38):4964-74.
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The homeodomain of Eyeless regulates cell growth and antagonizes the paired domain-dependent retinal differentiation function. Protein Cell. 2015 Jan; 6(1):68-78.
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Chronological analysis with fluorescent timer reveals unique features of newly generated ß-cells. Diabetes. 2014 Oct; 63(10):3388-93.