p300-CBP Transcription Factors
"p300-CBP Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
| Descriptor ID |
D050880
|
| MeSH Number(s) |
D08.811.913.050.134.415.500.575 D12.776.930.680
|
| Concept/Terms |
p300-CBP Transcription Factors- p300-CBP Transcription Factors
- Transcription Factors, p300-CBP
- p300 CBP Transcription Factors
- p300-CBP Coactivator
- Coactivator, p300-CBP
- p300 CBP Coactivator
- p300-CBP Protein
- p300 CBP Protein
|
Below are MeSH descriptors whose meaning is more general than "p300-CBP Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "p300-CBP Transcription Factors".
This graph shows the total number of publications written about "p300-CBP Transcription Factors" by people in this website by year, and whether "p300-CBP Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 2 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "p300-CBP Transcription Factors" by people in Profiles.
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MnTE-2-PyP modulates thiol oxidation in a hydrogen peroxide-mediated manner in a human prostate cancer cell. Free Radic Biol Med. 2016 12; 101:32-43.
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Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas. PLoS One. 2015; 10(11):e0142130.
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Repression of Ccr9 transcription in mouse T lymphocyte progenitors by the Notch signaling pathway. J Immunol. 2015 Apr 01; 194(7):3191-200.
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Modulation of reactivation of latent herpes simplex virus 1 in ganglionic organ cultures by p300/CBP and STAT3. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):E2621-8.
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Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. 2013 Apr 25; 153(3):678-91.
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Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer. Cell. 2013 Feb 14; 152(4):859-72.
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The RB tumor suppressor positively regulates transcription of the anti-angiogenic protein NOL7. Neoplasia. 2012 Dec; 14(12):1213-22.
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Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes. Mol Cell Biol. 2011 Jun; 31(11):2349-63.
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Effects of the SANT domain of tension-induced/inhibited proteins (TIPs), novel partners of the histone acetyltransferase p300, on p300 activity and TIP-6-induced adipogenesis. Mol Cell Biol. 2008 Oct; 28(20):6358-72.
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HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. J Biol Chem. 2008 Apr 11; 283(15):10135-46.