 Protein Stability
"Protein Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a protein to retain its structural conformation or its activity when subjected to physical or chemical manipulations.
| Descriptor ID |
D055550
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| MeSH Number(s) |
G02.111.700
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| Concept/Terms |
Protein Stability- Protein Stability
- Protein Stabilities
- Stabilities, Protein
- Stability, Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Stability".
Below are MeSH descriptors whose meaning is more specific than "Protein Stability".
This graph shows the total number of publications written about "Protein Stability" by people in this website by year, and whether "Protein Stability" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 0 | 5 | 5 | | 2010 | 0 | 5 | 5 | | 2011 | 0 | 7 | 7 | | 2012 | 0 | 3 | 3 | | 2013 | 0 | 10 | 10 | | 2014 | 0 | 12 | 12 | | 2015 | 0 | 2 | 2 | | 2016 | 0 | 7 | 7 | | 2017 | 0 | 10 | 10 | | 2018 | 0 | 3 | 3 | | 2019 | 0 | 2 | 2 | | 2020 | 0 | 5 | 5 | | 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Protein Stability" by people in Profiles.
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Shorthouse D, Hall BA. SARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability. J Chem Inf Model. 2021 09 27; 61(9):4152-4155.
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Mallis RJ, Duke-Cohan JS, Das DK, Akitsu A, Luoma AM, Banik D, Stephens HM, Tetteh PW, Castro CD, Krahnke S, Hussey RE, Lawney B, Brazin KN, Reche PA, Hwang W, Adams EJ, Lang MJ, Reinherz EL. Molecular design of the ?dT cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing. Proc Natl Acad Sci U S A. 2021 06 29; 118(26).
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Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
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Hochberg GKA, Liu Y, Marklund EG, Metzger BPH, Laganowsky A, Thornton JW. A hydrophobic ratchet entrenches molecular complexes. Nature. 2020 12; 588(7838):503-508.
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Sun HL, Zhu AC, Gao Y, Terajima H, Fei Q, Liu S, Zhang L, Zhang Z, Harada BT, He YY, Bissonnette MB, Hung MC, He C. Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.
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Jo S, Xu A, Curtis JE, Somani S, MacKerell AD. Computational Characterization of Antibody-Excipient Interactions for Rational Excipient Selection Using the Site Identification by Ligand Competitive Saturation-Biologics Approach. Mol Pharm. 2020 11 02; 17(11):4323-4333.
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Lee TH, Yeh CF, Lee YT, Shih YC, Chen YT, Hung CT, You MY, Wu PC, Shentu TP, Huang RT, Lin YS, Wu YF, Lin SJ, Lu FL, Tsao PN, Lin TH, Lo SC, Tseng YS, Wu WL, Chen CN, Wu CC, Lin SL, Sperling AI, Guzy RD, Fang Y, Yang KC. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFß signaling through TGFBR1 stabilization. Nat Commun. 2020 08 26; 11(1):4254.
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Fei Q, Zou Z, Roundtree IA, Sun HL, He C. YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators. PLoS Biol. 2020 04; 18(4):e3000664.
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Reitz D, Grubb J, Bishop DK. A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability. PLoS Genet. 2019 12; 15(12):e1008217.
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Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE. High throughput discovery of functional protein modifications by Hotspot Thermal Profiling. Nat Methods. 2019 09; 16(9):894-901.
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