Heat Shock Transcription Factors
"Heat Shock Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heat and cold stress-inducible, transcription factors that bind to inverted 5'-NGAAN-3' pentamer DNA sequences and are regulated by poly(ADP) ribosylation. They play essential roles as transcriptional activators of the HEAT-SHOCK RESPONSE by inducing expression of large classes of MOLECULAR CHAPERONES and heat-shock proteins. They also function in DNA REPAIR; transcriptional reactivation of latent HIV-1; and pre-mRNA processing and nuclear export of HSP70 HEAT-SHOCK PROTEINS during heat stress.
| Descriptor ID |
D000076249
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| MeSH Number(s) |
D12.776.157.687.450 D12.776.260.260 D12.776.660.720.462 D12.776.930.317
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Heat Shock Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Heat Shock Transcription Factors".
This graph shows the total number of publications written about "Heat Shock Transcription Factors" by people in this website by year, and whether "Heat Shock Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heat Shock Transcription Factors" by people in Profiles.
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The Heat Shock Response as a Condensate Cascade. J Mol Biol. 2024 Jul 15; 436(14):168642.
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Transcriptional regulation of Sis1 promotes fitness but not feedback in the heat shock response. Elife. 2023 05 09; 12.
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Regulation of Hsf1 and the Heat Shock Response. Adv Exp Med Biol. 2020; 1243:41-50.
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Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome. Mol Biol Cell. 2018 12 15; 29(26):3168-3182.
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Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis. Mol Cell. 2016 07 07; 63(1):60-71.
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Polyamines mediate glutamine-dependent induction of the intestinal epithelial heat shock response. Am J Physiol Gastrointest Liver Physiol. 2011 Jul; 301(1):G181-7.
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Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shock. Gastroenterology. 2005 Jul; 129(1):170-84.
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Biological functions of the ISWI chromatin remodeling complex NURF. Genes Dev. 2002 Dec 15; 16(24):3186-98.
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A transcriptional feedback loop for tissue-specific expression of highly cytotoxic genes which incorporates an immunostimulatory component. Gene Ther. 2001 Jul; 8(13):987-98.
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Laboratory selection at different temperatures modifies heat-shock transcription factor (HSF) activation in Drosophila melanogaster. J Exp Biol. 2001 Jan; 204(Pt 2):315-23.