"I-kappa B Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
| Descriptor ID |
D020672
|
| MeSH Number(s) |
D12.644.360.365 D12.776.260.420 D12.776.476.381 D12.776.930.326
|
| Concept/Terms |
I-kappa B Proteins- I-kappa B Proteins
- I kappa B Proteins
- I kappa B
- IkB DNA-Binding Proteins
- IkB DNA Binding Proteins
- I-kappa B
|
Below are MeSH descriptors whose meaning is more general than "I-kappa B Proteins".
Below are MeSH descriptors whose meaning is more specific than "I-kappa B Proteins".
This graph shows the total number of publications written about "I-kappa B Proteins" by people in this website by year, and whether "I-kappa B Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 0 | 3 |
| 1998 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2000 | 4 | 3 | 7 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 4 | 6 |
| 2004 | 1 | 2 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 3 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 5 | 5 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "I-kappa B Proteins" by people in Profiles.
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XPO1 Inhibitor Selinexor Overcomes Intrinsic Ibrutinib Resistance in Mantle Cell Lymphoma via Nuclear Retention of I?B. Mol Cancer Ther. 2018 12; 17(12):2564-2574.
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Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo. Appl Physiol Nutr Metab. 2015 Nov; 40(11):1129-36.
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MiR-196a exerts its oncogenic effect in glioblastoma multiforme by inhibition of I?Ba both in vitro and in vivo. Neuro Oncol. 2014 May; 16(5):652-61.
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Vitamin D regulates contractile profile in human uterine myometrial cells via NF-?B pathway. Am J Obstet Gynecol. 2014 Apr; 210(4):347.e1-347.e10.
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Spontaneous NF-?B activation by autocrine TNFa signaling: a computational analysis. PLoS One. 2013; 8(11):e78887.
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Functional variants in NFKBIE and RTKN2 involved in activation of the NF-?B pathway are associated with rheumatoid arthritis in Japanese. PLoS Genet. 2012 Sep; 8(9):e1002949.
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Enteropathogenic E. coli non-LEE encoded effectors NleH1 and NleH2 attenuate NF-?B activation. Mol Microbiol. 2010 Dec; 78(5):1232-45.
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MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13450-5.
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Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages. Biochem Biophys Res Commun. 2010 Jul 23; 398(2):284-9.
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Epithelial NF-kappaB enhances transmucosal fluid movement by altering tight junction protein composition after T cell activation. Am J Pathol. 2010 Jan; 176(1):158-67.