Immunoglobulin J Recombination Signal Sequence-Binding Protein
"Immunoglobulin J Recombination Signal Sequence-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed sequence-specific transcriptional repressor that is normally the target of signaling by NOTCH PROTEINS.
| Descriptor ID |
D051819
|
| MeSH Number(s) |
D12.776.260.457 D12.776.660.486 D12.776.930.327
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin J Recombination Signal Sequence-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin J Recombination Signal Sequence-Binding Protein".
This graph shows the total number of publications written about "Immunoglobulin J Recombination Signal Sequence-Binding Protein" by people in this website by year, and whether "Immunoglobulin J Recombination Signal Sequence-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin J Recombination Signal Sequence-Binding Protein" by people in Profiles.
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Noncanonical Notch signals have opposing roles during cardiac development. Biochem Biophys Res Commun. 2021 11 05; 577:12-16.
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Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis. Circ Res. 2016 05 13; 118(10):1480-97.
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Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation. Nat Cell Biol. 2015 Sep; 17(9):1193-204.
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Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null mice. J Immunol. 2010 Jul 01; 185(1):410-7.
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Direct inhibition of the NOTCH transcription factor complex. Nature. 2009 Nov 12; 462(7270):182-8.
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Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulation. J Biol Chem. 2008 Apr 18; 283(16):10476-84.
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Coordination of symmetric cyclic gene expression during somitogenesis by Suppressor of Hairless involves regulation of retinoic acid catabolism. Dev Biol. 2007 Jan 15; 301(2):388-403.
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Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation. J Virol. 2005 Jun; 79(12):7889-98.