Tumor Suppressor Protein p53
"Tumor Suppressor Protein p53" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.
| Descriptor ID |
D016159
|
| MeSH Number(s) |
D12.776.157.687.650 D12.776.260.820 D12.776.624.776.775 D12.776.660.720.650 D12.776.744.845
|
| Concept/Terms |
Tumor Suppressor Protein p53- Tumor Suppressor Protein p53
- p53 Antigen
- TP53 Protein
- TRP53 Protein
- p53 Tumor Suppressor Protein
- pp53 Phosphoprotein
- Phosphoprotein, pp53
- Cellular Tumor Antigen p53
- Oncoprotein p53
|
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor Protein p53".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor Protein p53".
This graph shows the total number of publications written about "Tumor Suppressor Protein p53" by people in this website by year, and whether "Tumor Suppressor Protein p53" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 2 | 0 | 2 |
| 1994 | 1 | 2 | 3 |
| 1995 | 3 | 3 | 6 |
| 1996 | 5 | 5 | 10 |
| 1997 | 2 | 3 | 5 |
| 1998 | 3 | 5 | 8 |
| 1999 | 1 | 1 | 2 |
| 2000 | 3 | 4 | 7 |
| 2001 | 4 | 2 | 6 |
| 2002 | 9 | 9 | 18 |
| 2003 | 7 | 2 | 9 |
| 2004 | 8 | 3 | 11 |
| 2005 | 6 | 4 | 10 |
| 2006 | 8 | 5 | 13 |
| 2007 | 3 | 6 | 9 |
| 2008 | 4 | 10 | 14 |
| 2009 | 5 | 3 | 8 |
| 2010 | 9 | 5 | 14 |
| 2011 | 9 | 8 | 17 |
| 2012 | 5 | 7 | 12 |
| 2013 | 5 | 1 | 6 |
| 2014 | 7 | 5 | 12 |
| 2015 | 7 | 5 | 12 |
| 2016 | 6 | 4 | 10 |
| 2017 | 8 | 4 | 12 |
| 2018 | 5 | 6 | 11 |
| 2019 | 7 | 7 | 14 |
| 2020 | 5 | 3 | 8 |
| 2021 | 4 | 2 | 6 |
| 2022 | 4 | 6 | 10 |
To return to the timeline,
click here.
Below are the most recent publications written about "Tumor Suppressor Protein p53" by people in Profiles.
-
Disparities in receiving disease-directed therapy, allogeneic stem cell transplantation in non-Hispanic Black patients with TP53-mutated acute myeloid leukemia. Cancer. 2023 Mar 15; 129(6):934-945.
-
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition. Nat Commun. 2022 10 20; 13(1):6206.
-
RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling. Biochim Biophys Acta Rev Cancer. 2022 Sep; 1877(5):188803.
-
TP53/PLCG2-mutated diffuse large B-cell lymphoma richter transformation (DLBCL-RT) of CLL with unusual CD2 and PD-1 expression. Leuk Lymphoma. 2022 11; 63(11):2735-2738.
-
TP53 mutation defines a unique subgroup within complex karyotype de?novo and therapy-related MDS/AML. Blood Adv. 2022 05 10; 6(9):2847-2853.
-
Long-term male-specific chronic pain via telomere- and p53-mediated spinal cord cellular senescence. J Clin Invest. 2022 04 15; 132(8).
-
Outcomes of TP53-mutated AML with evolving frontline therapies: Impact of allogeneic stem cell transplantation on survival. Am J Hematol. 2022 07; 97(7):E232-E235.
-
Differences in somatic TP53 mutation type in breast tumors by race and receptor status. Breast Cancer Res Treat. 2022 Apr; 192(3):639-648.
-
High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13. Acta Neuropathol. 2022 03; 143(3):403-414.
-
The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling. Nat Immunol. 2022 02; 23(2):287-302.