 NF-kappa B
"NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
| Descriptor ID |
D016328
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| MeSH Number(s) |
D12.776.260.600 D12.776.660.600 D12.776.930.600
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| Concept/Terms |
NF-kappa B- NF-kappa B
- kappa B Enhancer Binding Protein
- NF-kappaB
- NF kappaB
- Transcription Factor NF-kB
- Factor NF-kB, Transcription
- NF-kB, Transcription Factor
- Transcription Factor NF kB
- NF-kB
- NF kB
- Immunoglobulin Enhancer-Binding Protein
- Enhancer-Binding Protein, Immunoglobulin
- Immunoglobulin Enhancer Binding Protein
- Nuclear Factor kappa B
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Below are MeSH descriptors whose meaning is more general than "NF-kappa B".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B".
This graph shows the total number of publications written about "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1990 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 | | 1992 | 2 | 1 | 3 | | 1993 | 5 | 0 | 5 | | 1994 | 4 | 1 | 5 | | 1995 | 4 | 1 | 5 | | 1996 | 5 | 0 | 5 | | 1997 | 7 | 2 | 9 | | 1998 | 1 | 3 | 4 | | 1999 | 2 | 3 | 5 | | 2000 | 8 | 5 | 13 | | 2001 | 8 | 4 | 12 | | 2002 | 12 | 7 | 19 | | 2003 | 13 | 6 | 19 | | 2004 | 11 | 8 | 19 | | 2005 | 7 | 3 | 10 | | 2006 | 11 | 8 | 19 | | 2007 | 11 | 10 | 21 | | 2008 | 6 | 4 | 10 | | 2009 | 8 | 13 | 21 | | 2010 | 3 | 11 | 14 | | 2011 | 6 | 4 | 10 | | 2012 | 6 | 14 | 20 | | 2013 | 7 | 11 | 18 | | 2014 | 3 | 2 | 5 | | 2015 | 4 | 10 | 14 | | 2016 | 1 | 9 | 10 | | 2017 | 3 | 4 | 7 | | 2018 | 3 | 3 | 6 | | 2019 | 3 | 4 | 7 | | 2020 | 5 | 2 | 7 | | 2021 | 4 | 6 | 10 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "NF-kappa B" by people in Profiles.
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Semina SE, Pal P, Kansara NS, Huggins RJ, Alarid ET, Greene GL, Frasor J. Selective pressure of endocrine therapy activates the integrated stress response through NF?B signaling in a subpopulation of ER positive breast cancer cells. Breast Cancer Res. 2022 03 09; 24(1):19.
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Arora R, Van Theemsche KM, Van Remoortel S, Snyders DJ, Labro AJ, Timmermans JP. Constitutive, Basal, and ß-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on NF-?B Signaling. Int J Mol Sci. 2021 Dec 09; 22(24).
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Coccaro EF, Irwin M, Arevalo JMG, Dizon T, Cole S. Gene expression in peripheral blood mononuclear cells in impulsive aggression: Intermittent explosive disorder compared with non-aggressive healthy and psychiatric controls. Psychoneuroendocrinology. 2022 02; 136:105453.
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Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021 04 12; 12(1):2183.
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Voce DJ, Bernal GM, Cahill KE, Wu L, Mansour N, Crawley CD, Campbell PS, Arina A, Weichselbaum RR, Yamini B. CDK1 is up-regulated by temozolomide in an NF-?B dependent manner in glioblastoma. Sci Rep. 2021 03 11; 11(1):5665.
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Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands. ACS Chem Biol. 2021 02 19; 16(2):380-388.
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Son M, Wang AG, Tu HL, Metzig MO, Patel P, Husain K, Lin J, Murugan A, Hoffmann A, Tay S. NF-?B responds to absolute differences in cytokine concentrations. Sci Signal. 2021 01 19; 14(666).
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Vecchiotti D, Verzella D, Capece D, Nolfi MDV, Di Francesco B, Cornice J, Franzoso G, Alesse E, Zazzeroni F. Biochemical Methods to Analyze the Subcellular Localization of NF-?B Proteins Using Cell Fractionation. Methods Mol Biol. 2021; 2366:19-25.
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Vecchiotti D, Verzella D, Capece D, Cornice J, Nolfi MDV, Di Francesco B, Franzoso G, Alesse E, Zazzeroni F. Immunohistochemical Analysis of Expression, Phosphorylation, and Nuclear Translocation of NF-?B Proteins in Human Tissues. Methods Mol Biol. 2021; 2366:27-42.
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Capece D, Verzella D, Begalli F, Bennett J, D'Andrea D, Vecchiotti D, Zazzeroni F, Franzoso G. Extracellular Flux Analysis to Investigate the Impact of NF-?B on Mitochondrial Respiration in Colorectal Carcinoma (CRC). Methods Mol Biol. 2021; 2366:293-303.
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