 Proto-Oncogene Proteins c-fos
"Proto-Oncogene Proteins c-fos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
| Descriptor ID |
D016760
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| MeSH Number(s) |
D12.776.260.108.765 D12.776.624.664.700.179 D12.776.660.760 D12.776.930.127.765
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| Concept/Terms |
Proto-Oncogene Proteins c-fos- Proto-Oncogene Proteins c-fos
- Proto Oncogene Proteins c fos
- fos Proto-Oncogene Proteins
- fos Proto Oncogene Proteins
- Proto-Oncogene Proteins fos
- Proto Oncogene Proteins fos
- p55(c-fos)
- Proto-Oncogene Products c-fos
- Proto Oncogene Products c fos
- c-fos Proteins
- c fos Proteins
- p55 c-fos
- p55 c fos
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-fos".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-fos".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-fos" by people in this website by year, and whether "Proto-Oncogene Proteins c-fos" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1988 | 0 | 1 | 1 | | 1991 | 0 | 2 | 2 | | 1993 | 1 | 2 | 3 | | 1994 | 0 | 1 | 1 | | 1996 | 1 | 2 | 3 | | 1997 | 2 | 0 | 2 | | 1998 | 2 | 0 | 2 | | 1999 | 0 | 2 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 2 | 3 | | 2002 | 4 | 3 | 7 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 3 | 3 | | 2005 | 1 | 3 | 4 | | 2007 | 2 | 2 | 4 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 1 | 1 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 3 | 4 | 7 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-fos" by people in Profiles.
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You JC, Muralidharan K, Park JW, Petrof I, Pyfer MS, Corbett BF, LaFrancois JJ, Zheng Y, Zhang X, Mohila CA, Yoshor D, Rissman RA, Nestler EJ, Scharfman HE, Chin J. Epigenetic suppression of hippocampal calbindin-D28k by ?FosB drives seizure-related cognitive deficits. Nat Med. 2017 Nov; 23(11):1377-1383.
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Corbett BF, You JC, Zhang X, Pyfer MS, Tosi U, Iascone DM, Petrof I, Hazra A, Fu CH, Stephens GS, Ashok AA, Aschmies S, Zhao L, Nestler EJ, Chin J. ?FosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer's Disease. Cell Rep. 2017 07 11; 20(2):344-355.
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Sun YY, Zhang WJ, Dong CL, Zhang XF, Ji J, Wang X, Wang L, Hu WL, Du WJ, Cui CL, Zhang CF, Li F, Wang CZ, Yuan CS. Baicalin Alleviates Nitroglycerin-induced Migraine in Rats via the Trigeminovascular System. Phytother Res. 2017 Jun; 31(6):899-905.
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Cui CL, He X, Dong CL, Song ZJ, Ji J, Wang X, Wang L, Wang JY, Du WJ, Wang CZ, Yuan CS, Guo CR, Zhang CF. The enhancement mechanism of wine-processed Radix Scutellaria on NTG-induced migraine rats. Biomed Pharmacother. 2017 Jul; 91:138-146.
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Trevaskis JL, Sacramento CB, Jouihan H, Ali S, Le Lay J, Oldham S, Bhagroo N, Boland BB, Cann J, Chang Y, O'Day T, Howard V, Reers C, Winzell MS, Smith DM, Feigh M, Barkholt P, Schreiter K, Austen M, Andag U, Thompson S, Jermutus L, Coghlan MP, Grimsby J, Dohrmann C, Rhodes CJ, Rondinone CM, Sharma A. Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats. Diabetes. 2017 07; 66(7):2007-2018.
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Zhang XF, Zhang WJ, Dong CL, Hu WL, Sun YY, Bao Y, Zhang CF, Guo CR, Wang CZ, Yuan CS. Analgesia effect of baicalein against NTG-induced migraine in rats. Biomed Pharmacother. 2017 Jun; 90:116-121.
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Kesarwani M, Kincaid Z, Gomaa A, Huber E, Rohrabaugh S, Siddiqui Z, Bouso MF, Latif T, Xu M, Komurov K, Mulloy JC, Cancelas JA, Grimes HL, Azam M. Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia. Nat Med. 2017 Apr; 23(4):472-482.
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Singer BF, Bubula N, Li D, Przybycien-Szymanska MM, Bindokas VP, Vezina P. Drug-Paired Contextual Stimuli Increase Dendritic Spine Dynamics in Select Nucleus Accumbens Neurons. Neuropsychopharmacology. 2016 07; 41(8):2178-87.
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Antonescu CR, Chen HW, Zhang L, Sung YS, Panicek D, Agaram NP, Dickson BC, Krausz T, Fletcher CD. ZFP36-FOSB fusion defines a subset of epithelioid hemangioma with atypical features. Genes Chromosomes Cancer. 2014 Nov; 53(11):951-9.
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Ha J, Kim HJ, Huang H, Lee ZH, Kim HH. Mitogen- and stress-activated protein kinase 1 activates osteoclastogenesis in vitro and affects bone destruction in vivo. J Mol Med (Berl). 2013 Aug; 91(8):977-87.
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