 Proto-Oncogene Proteins c-crk
"Proto-Oncogene Proteins c-crk" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transducing adaptor proteins that contain SRC HOMOLOGY DOMAINS and play a role in CYTOSKELETON reorganization. c-crk protein is closely related to ONCOGENE PROTEIN V-CRK and includes several alternatively spliced isoforms.
| Descriptor ID |
D050737
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| MeSH Number(s) |
D12.644.360.024.318 D12.776.157.057.139 D12.776.476.024.409 D12.776.624.664.700.174
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| Concept/Terms |
Proto-Oncogene Proteins c-crk- Proto-Oncogene Proteins c-crk
- Proteins c-crk, Proto-Oncogene
- Proto Oncogene Proteins c crk
- c-crk, Proto-Oncogene Proteins
- Proto-Oncogene Protein c-crk
- Proto Oncogene Protein c crk
- c-crk, Proto-Oncogene Protein
- crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, crk
- crk Proto Oncogene Proteins
- CT10 Regulator of Kinase Protein
- c-crk Protein
- c-crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, c-crk
- c crk Proto Oncogene Proteins
Proto-Oncogene Protein c-crk-2- Proto-Oncogene Protein c-crk-2
- Proto Oncogene Protein c crk 2
- c-crk-2, Proto-Oncogene Protein
- CRKII Protein
- Crk-2 Protein
- Crk 2 Protein
- CrkII Adapter Protein
- Adapter Protein, CrkII
- c-crk-2 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-2
- c crk 2 Proto Oncogene Protein
- c-CrkII Protein
- c CrkII Protein
Proto-Oncogene Protein c-crk-3- Proto-Oncogene Protein c-crk-3
- Proto Oncogene Protein c crk 3
- c-crk-3, Proto-Oncogene Protein
- CrkIII Protein
- Crk3 Protein
- c-crk-3 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-3
- c crk 3 Proto Oncogene Protein
- c-CrkIII Protein
- c CrkIII Protein
Proto-Oncogene Protein c-crk-1- Proto-Oncogene Protein c-crk-1
- Proto Oncogene Protein c crk 1
- c-crk-1, Proto-Oncogene Protein
- CRKI Protein
- Crk-1 Protein
- Crk 1 Protein
- c-crk-I Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-I
- c crk I Proto Oncogene Protein
- c-crkI Protein
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-crk".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-crk".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-crk" by people in this website by year, and whether "Proto-Oncogene Proteins c-crk" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Proto-Oncogene Proteins c-crk" by people in Profiles.
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Imamoto A, Ki S, Li L, Iwamoto K, Maruthamuthu V, Devany J, Lu O, Kanazawa T, Zhang S, Yamada T, Hirayama A, Fukuda S, Suzuki Y, Okada M. Essential role of the Crk family-dosage in DiGeorge-like anomaly and metabolic homeostasis. Life Sci Alliance. 2020 02; 3(2).
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Hale BG, Steel J, Manicassamy B, Medina RA, Ye J, Hickman D, Lowen AC, Perez DR, García-Sastre A. Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus. J Gen Virol. 2010 Jul; 91(Pt 7):1737-42.
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Seo JH, Suenaga A, Hatakeyama M, Taiji M, Imamoto A. Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop. Mol Cell Biol. 2009 Jun; 29(11):3076-87.
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Moon AM, Guris DL, Seo JH, Li L, Hammond J, Talbot A, Imamoto A. Crkl deficiency disrupts Fgf8 signaling in a mouse model of 22q11 deletion syndromes. Dev Cell. 2006 Jan; 10(1):71-80.
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Platanias LC, Uddin S, Bruno E, Korkmaz M, Ahmad S, Alsayed Y, Van Den Berg D, Druker BJ, Wickrema A, Hoffman R. CrkL and CrkII participate in the generation of the growth inhibitory effects of interferons on primary hematopoietic progenitors. Exp Hematol. 1999 Aug; 27(8):1315-21.
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Sorokin A, Reed E, Nnkemere N, Dulin NO, Schlessinger J. Crk protein binds to PDGF receptor and insulin receptor substrate-1 with different modulating effects on PDGF- and insulin-dependent signaling pathways. Oncogene. 1998 May 14; 16(19):2425-34.
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Uemura N, Salgia R, Li JL, Pisick E, Sattler M, Griffin JD. The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins. Leukemia. 1997 Mar; 11(3):376-85.
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Sattler M, Salgia R, Okuda K, Uemura N, Durstin MA, Pisick E, Xu G, Li JL, Prasad KV, Griffin JD. The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway. Oncogene. 1996 Feb 15; 12(4):839-46.
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