Interferon-Stimulated Gene Factor 3
"Interferon-Stimulated Gene Factor 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.
|Interferon-Stimulated Gene Factor 3
- Interferon-Stimulated Gene Factor 3
- Interferon Stimulated Gene Factor 3
- Transcription Factor ISGF3
- ISGF3, Transcription Factor
- ISGF3 Transcription Factor
- Transcription Factor, ISGF3
- IFN-Stimulated Gene Factor 3 Complex
- IFN Stimulated Gene Factor 3 Complex
- ISGF3 Factor
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Below are MeSH descriptors whose meaning is more specific than "Interferon-Stimulated Gene Factor 3".
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Below are the most recent publications written about "Interferon-Stimulated Gene Factor 3" by people in Profiles.
Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol. 2004 Apr; 78(8):4185-96.
Induction of endothelial-leukocyte interaction by interferon-gamma requires coactivation of nuclear factor-kappaB. Arterioscler Thromb Vasc Biol. 2001 Feb; 21(2):227-32.
Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1. Genes Dev. 1996 Sep 15; 10(18):2335-47.