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Concept Acute Disease
Concept Adenine
Concept Actins
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Concept Aged, 80 and over
Concept Aldosterone
Concept Atropine Derivatives
Concept Arteriovenous Malformations
Concept Acetylcholine
Concept Adaptation, Physiological
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Concept Cyclic AMP
Concept Berberine
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Concept Biphenyl Compounds
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Concept Blood Platelets
Concept Bone Marrow Cells
Concept Amino Acid Sequence
Concept Adenosine Triphosphate
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Concept Boston
Concept Apolipoproteins E
Concept Hypoxia, Brain
Concept Androstadienes
Concept Angina Pectoris
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Aorta
Concept Calmodulin
Concept Aminoquinolines
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Concept Antioxidants
Concept Analysis of Variance
Concept Anions
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Concept B-Lymphocytes
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Concept Cell Differentiation
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Concept Cerebral Infarction
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Concept Binding Sites
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Concept Basilar Artery
Concept Bleomycin
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Concept Botulinum Toxins
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Concept Cell Cycle
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Concept C-Reactive Protein
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Concept Circadian Rhythm
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Concept Clotrimazole
Concept Coronary Artery Disease
Concept Diabetes Mellitus, Type 1
Concept Huntington Disease
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Concept Imidazoles
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Concept Cytochrome P-450 Enzyme System
Concept Cytoskeleton
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Concept Dogs
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Concept Dipyridamole
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Concept Illinois
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Concept Middle Aged
Concept Receptors, Angiotensin
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Concept Neural Tube Defects
Concept Lipopolysaccharides
Concept Cholesterol, HDL
Concept Salicylates
Concept Patient Discharge
Concept Sodium Salicylate
Concept Phosphorylation
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Concept Tissue Plasminogen Activator
Concept Platelet Aggregation
Concept Protein Binding
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Concept Homocysteine
Concept Immunoglobulin G
Concept Regional Blood Flow
Concept Heart Septal Defects, Ventricular
Concept Rabbits
Concept Quinolines
Concept Quinoxalines
Concept Cohort Studies
Concept Receptors, Adrenergic, alpha
Concept Smoking
Concept RNA Processing, Post-Transcriptional
Concept Mass Spectrometry
Concept Swine
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Concept Humans
Concept Body Mass Index
Concept Bone Marrow Transplantation
Concept Ticlopidine
Concept Transcription, Genetic
Concept Protein Biosynthesis
Concept Tetrazoles
Concept Superoxides
Concept Triiodothyronine
Concept Stroke Volume
Concept Tumor Necrosis Factor-alpha
Concept Plasminogen Activator Inhibitor 1
Concept Drug Design
Concept Ultraviolet Rays
Concept Biomarkers
Concept Cholesterol, LDL
Concept Caspases
Concept Peptide Elongation Factor 1
Concept RGS Proteins
Concept rho GTP-Binding Proteins
Concept rhoB GTP-Binding Protein
Concept Tyrosine
Concept rac1 GTP-Binding Protein
Concept Raloxifene Hydrochloride
Concept Veratrine
Concept Up-Regulation
Concept Mice, Inbred ICR
Concept Carotid Stenosis
Concept Mitochondria
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Concept Second Messenger Systems
Concept CD4-Positive T-Lymphocytes
Concept Radionuclide Ventriculography
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Concept Proto-Oncogene Proteins c-fos
Concept Cytochalasin D
Concept Eicosanoids
Concept Rats, Sprague-Dawley
Concept Rats, Wistar
Concept Case-Control Studies
Concept Protein Structure, Tertiary
Concept Motor Activity
Concept Myosins
Concept Angiopoietin-2
Concept Neurites
Concept Bronchial Hyperreactivity
Concept Hypertrophy, Left Ventricular
Concept Arachidonic Acid
Concept Apoptosis
Concept Annexin A5
Concept Mice, Knockout
Concept Receptors, AMPA
Concept Cell Proliferation
Concept GTP-Binding Protein alpha Subunits, Gs
Concept omega-N-Methylarginine
Concept ras Proteins
Concept Interferon-Stimulated Gene Factor 3
Concept Th2 Cells
Concept Infarction, Middle Cerebral Artery
Concept GTP-Binding Protein alpha Subunits, Gi-Go
Concept Bone Morphogenetic Protein Receptors, Type II
Concept Caspase 3
Concept Cross-Over Studies
Concept Ankle Brachial Index
Concept Intracranial Embolism
Concept Matrix Metalloproteinase 2
Concept Cyclic GMP-Dependent Protein Kinases
Concept Pertussis Toxin
Concept Receptor, Angiotensin, Type 2
Concept Atherosclerosis
Concept Vascular Endothelial Growth Factors
Concept Catenins
Concept Sterol Regulatory Element Binding Protein 2
Concept Angiotensin II Type 1 Receptor Blockers
Concept COS Cells
Concept Transcription Factor AP-1
Concept 3' Untranslated Regions
Concept Hydroxymethylglutaryl-CoA Reductase Inhibitors
Concept ras GTPase-Activating Proteins
Concept rhoA GTP-Binding Protein
Concept rac GTP-Binding Proteins
Concept Platelet Endothelial Cell Adhesion Molecule-1
Concept Cationic Amino Acid Transporter 1
Concept Goblet Cells
Concept Hemangioma, Cavernous, Central Nervous System
Concept Cyclin-Dependent Kinase Inhibitor p21
Concept Popliteal Artery
Concept Precipitin Tests
Concept Promoter Regions, Genetic
Concept Mice
Concept Early Growth Response Protein 1
Concept Pulmonary Artery
Concept Pyrroles
Concept Rats, Inbred Strains
Concept Acute Coronary Syndrome
Concept Glycogen Synthase Kinase 3
Concept Prenylation
Concept Structure-Activity Relationship
Concept Interferon Regulatory Factors
Concept Rats
Concept Nitric Oxide Synthase Type II
Concept Period Circadian Proteins
Concept Adaptor Proteins, Signal Transducing
Concept Chemokine CXCL10
Concept Blotting, Western
Concept Down-Regulation
Concept Multivariate Analysis
Concept Cyclins
Concept Angiotensin II Type 2 Receptor Blockers
Concept Tibial Arteries
Concept Phosphatidylinositol 3-Kinase
Concept 8,11,14-Eicosatrienoic Acid
Concept Blotting, Northern
Concept Molecular Structure
Concept Platelet Activation
Concept Cell Hypoxia
Concept ATP-Binding Cassette Transporters
Concept Coronary Angiography
Concept Cyclin-Dependent Kinases
Concept Protein Prenylation
Concept GTP-Binding Proteins
Concept NG-Nitroarginine Methyl Ester
Concept Myeloid Differentiation Factor 88
Concept Mitogen-Activated Protein Kinase 1
Concept Intracranial Hemorrhages
Concept Interleukin-17
Concept Stroke
Concept cdc42 GTP-Binding Protein
Concept Interleukin-13
Concept Blood Vessel Prosthesis Implantation
Concept Carotid Artery Injuries
Concept Monomeric GTP-Binding Proteins
Concept GTPase-Activating Proteins
Concept MAP Kinase Signaling System
Concept Extracellular Signal-Regulated MAP Kinases
Concept gamma Catenin
Concept Basic Helix-Loop-Helix Transcription Factors
Concept Keratin-14
Concept Angiotensin Receptor Antagonists
Concept RNA, Small Interfering
Concept Vascular Endothelial Growth Factor A
Concept GTP-Binding Protein alpha Subunits, Gq-G11
Concept Cell Line, Tumor
Concept Cyclin-Dependent Kinase Inhibitor p27
Concept Nuclear Receptor Coactivator 3
Concept Anticholesteremic Agents
Concept Hypolipidemic Agents
Concept Arteriosclerosis
Concept Brain Neoplasms
Concept Calcium
Concept Calcium Channel Blockers
Concept Cerebral Arteries
Concept Brain Ischemia
Concept Coronary Vessels
Concept Desmosomes
Concept Femoral Artery
Concept Follow-Up Studies
Concept Kinetics
Concept Longitudinal Studies
Concept Mice, Mutant Strains
Concept Monocytes
Concept Prospective Studies
Concept Retrospective Studies
Concept Sphingosine
Concept T-Lymphocytes
Concept Violence
Concept Signal Transduction
Concept Interleukin-5
Concept Tumor Suppressor Protein p53
Concept Cyclic AMP-Dependent Protein Kinases
Concept Porins
Concept 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Concept Nitroarginine
Concept Chemokines, CXC
Concept Losartan
Concept Proto-Oncogene Proteins c-sis
Concept RNA Stability
Concept Adherens Junctions
Concept Adaptor Proteins, Vesicular Transport
Concept MicroRNAs
Concept ADP Ribose Transferases
Concept Vascular Endothelial Growth Factor Receptor-1
Concept Estrogen Receptor alpha
Concept Proto-Oncogene Proteins c-akt
Concept Smad Proteins
Concept Young Adult
Concept HLA-DR alpha-Chains
Academic Article Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase.
Academic Article Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene.
Academic Article Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.
Academic Article Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
Academic Article Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.
Academic Article Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy.
Academic Article Increased Rho kinase activity in a Taiwanese population with metabolic syndrome.
Academic Article Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2.
Academic Article Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2.
Academic Article Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage.
Academic Article A method for measuring Rho kinase activity in tissues and cells.
Academic Article Essential role of endothelial Notch1 in angiogenesis.
Academic Article Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection.
Academic Article Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
Academic Article Smooth muscle Notch1 mediates neointimal formation after vascular injury.
Academic Article Notch1 in bone marrow-derived cells mediates cardiac repair after myocardial infarction.
Academic Article Squalene synthase inhibitor lapaquistat acetate: could anything be better than statins?
Academic Article Increased Rho kinase activity in congestive heart failure.
Academic Article Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.
Academic Article Statins inhibit Rho kinase activity in patients with atherosclerosis.
Academic Article Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy.
Academic Article Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease.
Academic Article Role of Rho kinase isoforms in murine allergic airway responses.
Academic Article Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil.
Academic Article Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis.
Academic Article Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR-/- mice.
Academic Article Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness.
Academic Article Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen.
Academic Article Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation.
Academic Article Rho kinase: an important mediator of atherosclerosis and vascular disease.
Academic Article Notch signaling regulates endothelial progenitor cell activity during recovery from arterial injury in hypercholesterolemic mice.
Academic Article Rho-associated kinase activity, endothelial function, and cardiovascular risk factors.
Academic Article Induction of endothelial-leukocyte interaction by interferon-gamma requires coactivation of nuclear factor-kappaB.
Academic Article Inhibition of vascular smooth muscle cell proliferation by sodium salicylate mediated by upregulation of p21(Waf1) and p27(Kip1).
Academic Article Rapid effects of statins: from prophylaxis to therapy for ischemic stroke.
Academic Article Non-nuclear actions of estrogen: new targets for prevention and treatment of cardiovascular disease.
Academic Article Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthase.
Academic Article Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol.
Academic Article Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt.
Academic Article Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors.
Academic Article A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms.
Academic Article Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells.
Academic Article Endothelium-dependent effects of statins.
Academic Article Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease.
Academic Article Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors.
Academic Article Nonnuclear actions of estrogen.
Academic Article Isoprenoid metabolism and the pleiotropic effects of statins.
Academic Article Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation.
Academic Article Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases.
Academic Article Does it matter whether or not a lipid-lowering agent inhibits Rho kinase?
Academic Article Mitohormesis: another pleiotropic effect of statins?
Academic Article gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.
Academic Article ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression.
Academic Article Pleiotropic effects of statins.
Academic Article FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1.
Academic Article Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction.
Academic Article Translational therapeutics of dipyridamole.
Academic Article Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event.
Academic Article Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Academic Article Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription.
Academic Article Linking endothelial dysfunction with endothelial cell activation.
Academic Article The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor.
Academic Article Functional interaction of endothelial nitric oxide synthase with a voltage-dependent anion channel.
Academic Article The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.
Academic Article Rac1 is a critical mediator of endothelium-derived neurotrophic activity.
Academic Article Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase.
Academic Article Isoprenoids as mediators of the biological effects of statins.
Academic Article Phosphatidylinositol 3-kinase/protein kinase Akt negatively regulates plasminogen activator inhibitor type 1 expression in vascular endothelial cells.
Academic Article Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
Academic Article VEGF increases retinal vascular ICAM-1 expression in vivo.
Academic Article Safety and efficacy of statins in Asians.
Academic Article Inhibition of major histocompatibility complex class II gene transcription by nitric oxide and antioxidants.
Academic Article Statins and ischemic stroke.
Academic Article Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
Academic Article Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors.
Academic Article Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.
Academic Article 1alpha,25-dihydroxyvitamin D3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase.
Academic Article 3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1).
Academic Article Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase.
Academic Article A functional role of I kappa B-epsilon in endothelial cell activation.
Academic Article Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids.
Academic Article Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.
Academic Article Statins: potent vascular anti-inflammatory agents.
Academic Article Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.
Academic Article Cross-coupling between the oestrogen receptor and phosphoinositide 3-kinase.
Academic Article Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2.
Academic Article ROCKs as therapeutic targets in cardiovascular diseases.
Academic Article Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment.
Academic Article NF-?B and innate immunity in ischemic stroke.
Academic Article Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.
Academic Article Nontranscriptional actions of the glucocorticoid receptor.
Academic Article Acute myocardial infarction after ergonovine administration for uterine bleeding.
Academic Article Rho GTPases, statins, and nitric oxide.
Academic Article Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen.
Academic Article Activation of the phosphatidylinositol 3-kinase/protein kinase Akt pathway mediates nitric oxide-induced endothelial cell migration and angiogenesis.
Academic Article Neuroprotection mediated by changes in the endothelial actin cytoskeleton.
Academic Article Clinical implications for statin pleiotropy.
Academic Article ROCKs as immunomodulators of stroke.
Academic Article Pleiotropic effects of statin therapy: molecular mechanisms and clinical results.
Academic Article Physiological role of ROCKs in the cardiovascular system.
Academic Article Inhibition of Rho-kinase attenuates endothelial-leukocyte interaction during ischemia-reperfusion injury.
Academic Article Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Academic Article A combination of increased Rho kinase activity and N-terminal pro-B-type natriuretic peptide predicts worse cardiovascular outcome in patients with acute coronary syndrome.
Academic Article Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.
Academic Article Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.
Academic Article Regulation of myogenic terminal differentiation by the hairy-related transcription factor CHF2.
Academic Article Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IkappaBalpha.
Academic Article Requirement of Rac1 in the development of cardiac hypertrophy.
Academic Article ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Academic Article Potential serum biomarkers in the pathophysiological processes of stroke.
Academic Article Activation of Galpha s mediates induction of tissue-type plasminogen activator gene transcription by epoxyeicosatrienoic acids.
Academic Article Linking Notch signaling to ischemic stroke.
Academic Article [New findings on the action of HMG-CoA-reductase inhibitors].
Academic Article Modulation of bradykinin receptor ligand binding affinity and its coupled G-proteins by nitric oxide.
Academic Article Additive effects of statin and dipyridamole on cerebral blood flow and stroke protection.
Academic Article Simvastatin decreases IL-6 and IL-8 production in epithelial cells.
Academic Article Statin therapy: having the good without the bad.
Academic Article Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1.
Academic Article Statins and myocardial hypertrophy.
Academic Article Salicylates and vascular smooth muscle cell proliferation: molecular mechanisms for cell cycle arrest.
Academic Article Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway.
Academic Article Differential regulation of endothelial cell adhesion molecule expression by nitric oxide donors and antioxidants.
Academic Article Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase.
Academic Article Novel aspects of the roles of Rac1 GTPase in the cardiovascular system.
Academic Article Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase.
Academic Article Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1.
Academic Article Regulation of G-protein alpha i2 subunit expression by oxidized low-density lipoprotein.
Academic Article FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
Academic Article Inducible nitric oxide: an autoregulatory feedback inhibitor of vascular inflammation.
Academic Article Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase.
Academic Article Rapid nongenomic actions of thyroid hormone.
Academic Article Rho kinase (ROCK) inhibitors.
Academic Article NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy.
Academic Article Targeting eNOS and beyond: emerging heterogeneity of the role of endothelial Rho proteins in stroke protection.
Academic Article Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy.
Academic Article Fine-tuning the angiogenic response to vascular endothelial growth factor.
Academic Article Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.
Academic Article Protective effects of statins involving both eNOS and tPA in focal cerebral ischemia.
Academic Article Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase.
Academic Article Atorvastatin restores endothelial function in normocholesterolemic smokers independent of changes in low-density lipoprotein.
Academic Article MnTBAP stimulates angiogenic functions in endothelial cells through mitofusin-1.
Academic Article Effect of torcetrapib in patients at high risk for coronary events.
Academic Article ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Academic Article Statin therapy is associated with improved patency of autogenous infrainguinal bypass grafts.
Academic Article Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.
Academic Article Critical role of endothelial Notch1 signaling in postnatal angiogenesis.
Academic Article Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis.
Academic Article Distribution of sphingosine kinase activity and mRNA in rodent brain.
Academic Article HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events.
Academic Article Increased leukocyte ROCK activity in patients after acute ischemic stroke.
Academic Article Drug Insight: statins and stroke.
Academic Article Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.
Academic Article 11,12-epoxyeicosatrienoic acid (11,12-EET): structural determinants for inhibition of TNF-alpha-induced VCAM-1 expression.
Academic Article Relative Lack of Culprit and Obstructive Coronary Lesions in Patients With Acute Ischemic Stroke and Elevated Cardiac Troponin.
Academic Article Role of statin pleiotropism in acute coronary syndromes and stroke.
Academic Article Genetically elevated C-reactive protein and ischemic vascular disease.
Academic Article Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
Academic Article Rho Kinases and Cardiac Remodeling.
Academic Article Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.
Academic Article Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.
Academic Article Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding.
Academic Article Fingolimod provides long-term protection in rodent models of cerebral ischemia.
Academic Article RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Academic Article Activation of guanine nucleotide-binding proteins and induction of endothelial tissue-type plasminogen activator gene transcription by alcohol.
Academic Article Targeting Rho in cardiovascular disease.
Academic Article Lipid management with statins. The lower the better?
Academic Article Targeting eNOS for stroke protection.
Academic Article Nuclear run-on assay to study gene transcription in vascular cells.
Academic Article Specific receptor-guanine nucleotide binding protein interaction mediates the release of endothelium-derived relaxing factor.
Academic Article [Regulation of endothelial NO production by Rho GTPase].
Academic Article Tumor necrosis factor-alpha downregulates endothelial nitric oxide synthase mRNA stability via translation elongation factor 1-alpha 1.
Academic Article Direct vascular effects of HMG-CoA reductase inhibitors.
Academic Article Pleiotropic Effects of Statins on the Cardiovascular System.
Academic Article Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms.
Academic Article Preservation of NO production by statins in the treatment of heart failure.
Academic Article Simvastatin reverses cardiac hypertrophy caused by disruption of the bradykinin 2 receptor.
Academic Article Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.
Academic Article Beyond lipid lowering: the role of statins in vascular protection.
Academic Article Statin therapy for cardiac hypertrophy and heart failure.
Academic Article Cardiology Consultation in the Emergency Department Reduces Re-hospitalizations for Low-Socioeconomic Patients with Acute Decompensated Heart Failure.
Academic Article Tumor necrosis factor-a levels and non-surgical bleeding in continuous-flow left ventricular assist devices.
Academic Article Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction.
Academic Article Inhibition of MHC II gene transcription by nitric oxide and antioxidants.
Academic Article Acute reduction of myocardial infarct size by a hydroxymethyl glutaryl coenzyme A reductase inhibitor is mediated by endothelial nitric oxide synthase.
Academic Article Vascular protection by estrogen in ischemia-reperfusion injury requires endothelial nitric oxide synthase.
Academic Article ROCK as a therapeutic target for ischemic stroke.
Academic Article Simvastatin preserves cardiac function in genetically determined cardiomyopathy.
Academic Article The Pleiotropic Effects of Statins - From Coronary Artery Disease and Stroke to Atrial Fibrillation and Ventricular Tachyarrhythmia.
Academic Article Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.
Academic Article Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.
Academic Article Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4.
Academic Article Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.
Academic Article Is statin discontinuation an option in patients who have had a stroke?
Academic Article Role of angiotensin II receptor subtypes in porcine basilar artery: functional, radioligand binding, and cell culture studies.
Academic Article Dynamic regulation of endothelial NOS mediated by competitive interaction with alpha-actinin-4 and calmodulin.
Academic Article Association of Rising Violent Crime With Blood Pressure and Cardiovascular Risk: Longitudinal Evidence From Chicago, 2014-2016.
Academic Article A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Academic Article Community Health Workers Reduce Rehospitalizations and Emergency Department Visits for Low-Socioeconomic Urban Patients With Heart Failure.
Academic Article Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
Academic Article Long-term statin use and psychological well-being.
Academic Article Regulator of G-Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia.
Academic Article SALAD-BAAR: A numerical risk score for hospital admission or emergency department presentation in ambulatory patients with cardiovascular disease.
Academic Article Emerging views of statin pleiotropy and cholesterol lowering.
Academic Article Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury.
Academic Article Challenging Statin Pleiotropy: Preeclampsia.
Academic Article Vascular Stiffening Mediated by Rho-Associated Coiled-Coil Containing Kinase Isoforms.
Concept Fingolimod Hydrochloride
Concept Liver X Receptors
Concept Glycogen Synthase Kinase 3 beta
Concept KRIT1 Protein
Concept Percutaneous Coronary Intervention
Concept ATP Binding Cassette Transporter 1
Grant Endothelial Akt in Vascular Injury
Grant ROCK and Obesity
Academic Article Understanding the molecular mechanisms of statin pleiotropic effects.
Academic Article A Novel HIF-2a/ARNT Signaling Pathway Protects Against Microvascular Dysfunction and heart failure After Myocardial Infarction.
Academic Article Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations.
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