Item Type | Name |
Concept
|
Acetylation
|
Concept
|
Anticodon
|
Concept
|
Alkylation
|
Concept
|
Autophagy
|
Concept
|
Aerobiosis
|
Concept
|
Algorithms
|
Concept
|
Amination
|
Concept
|
Amino Acid Sequence
|
Concept
|
Catalysis
|
Concept
|
Anaerobiosis
|
Concept
|
Base Sequence
|
Concept
|
Cell Count
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Movement
|
Concept
|
Dealkylation
|
Concept
|
DNA Damage
|
Concept
|
Bacterial Outer Membrane Proteins
|
Concept
|
Bacterial Proteins
|
Concept
|
Binding Sites
|
Concept
|
Electrons
|
Concept
|
Fertility
|
Concept
|
Chromatography, Gel
|
Concept
|
Cell Cycle
|
Concept
|
Fungal Proteins
|
Concept
|
Gastrointestinal Neoplasms
|
Concept
|
Glutathione Peroxidase
|
Concept
|
Guinea Pigs
|
Concept
|
Circadian Rhythm
|
Concept
|
Hematopoiesis
|
Concept
|
Hydroxylation
|
Concept
|
DNA Transposable Elements
|
Concept
|
DNA-Binding Proteins
|
Concept
|
DNA Repair
|
Concept
|
Electrophoresis, Polyacrylamide Gel
|
Concept
|
Genes, Regulator
|
Concept
|
Gluconeogenesis
|
Concept
|
Exons
|
Concept
|
Environment
|
Concept
|
Fluorescence
|
Concept
|
Gene Expression Regulation
|
Concept
|
Deamination
|
Concept
|
Genetic Techniques
|
Concept
|
Gliadin
|
Concept
|
Glioma
|
Concept
|
Gluconates
|
Concept
|
Glycosylation
|
Concept
|
Genes, Bacterial
|
Concept
|
Gram-Positive Bacteria
|
Concept
|
Nucleic Acid Hybridization
|
Concept
|
Obesity
|
Concept
|
Oncogenes
|
Concept
|
Gold
|
Concept
|
Hydrogen-Ion Concentration
|
Concept
|
Peptide Chain Initiation, Translational
|
Concept
|
Erythropoiesis
|
Concept
|
Fourier Analysis
|
Concept
|
Germ Cells
|
Concept
|
Light
|
Concept
|
Iron-Sulfur Proteins
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Membrane Proteins
|
Concept
|
Hydrolysis
|
Concept
|
Monoclonal Gammopathy of Undetermined Significance
|
Concept
|
Mitosis
|
Concept
|
Models, Genetic
|
Concept
|
Nerve Tissue Proteins
|
Concept
|
Organ Size
|
Concept
|
Molecular Sequence Data
|
Concept
|
Glycolysis
|
Concept
|
Repetitive Sequences, Nucleic Acid
|
Concept
|
Mutation
|
Concept
|
Nerve Growth Factors
|
Concept
|
Neuronal Plasticity
|
Concept
|
Synaptic Transmission
|
Concept
|
Nucleosomes
|
Concept
|
Nucleic Acid Conformation
|
Concept
|
Oogenesis
|
Concept
|
Oxidation-Reduction
|
Concept
|
Stress, Physiological
|
Concept
|
Phosphorylation
|
Concept
|
Operon
|
Concept
|
Plasmids
|
Concept
|
Protein Precursors
|
Concept
|
Protein-Tyrosine Kinases
|
Concept
|
Protein Binding
|
Concept
|
Protein Conformation
|
Concept
|
Protein Processing, Post-Translational
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Proteins
|
Concept
|
Genetic Markers
|
Concept
|
Glucosyltransferases
|
Concept
|
Guanine
|
Concept
|
Guanosine
|
Concept
|
Haplotypes
|
Concept
|
Repressor Proteins
|
Concept
|
Protein Kinases
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
Concept
|
RNA Splicing
|
Concept
|
Spermatogenesis
|
Concept
|
RNA Processing, Post-Transcriptional
|
Concept
|
Sensitivity and Specificity
|
Concept
|
Homeostasis
|
Concept
|
Hydrogen Bonding
|
Concept
|
Time Factors
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Staphylococcal Protein A
|
Concept
|
Thermodynamics
|
Concept
|
Genome
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Virulence
|
Concept
|
Genetic Variation
|
Concept
|
Protein Engineering
|
Concept
|
Ultraviolet Rays
|
Concept
|
Codon, Terminator
|
Concept
|
Gene Rearrangement
|
Concept
|
Trans-Activators
|
Concept
|
Gene Library
|
Concept
|
DNA Adducts
|
Concept
|
Drug Resistance, Neoplasm
|
Concept
|
Protein Structure, Quaternary
|
Concept
|
Protein Subunits
|
Concept
|
RNA Splice Sites
|
Concept
|
Transcription Initiation Site
|
Concept
|
HMGA2 Protein
|
Concept
|
Up-Regulation
|
Concept
|
Genes, Tumor Suppressor
|
Concept
|
Mutagenesis
|
Concept
|
Genome, Bacterial
|
Concept
|
Zebrafish Proteins
|
Concept
|
Macrophage Activation
|
Concept
|
Molecular Conformation
|
Concept
|
Gene Expression
|
Concept
|
Proto-Oncogene Proteins c-myc
|
Concept
|
RNA Interference
|
Concept
|
Alternative Splicing
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Methylation
|
Concept
|
Genes, Reporter
|
Concept
|
Morphogenesis
|
Concept
|
Consensus Sequence
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Apoptosis
|
Concept
|
Gene Deletion
|
Concept
|
Sequence Deletion
|
Concept
|
Gene Expression Regulation, Developmental
|
Concept
|
Cell Proliferation
|
Concept
|
Oxidative Stress
|
Concept
|
Evolution, Molecular
|
Concept
|
Nonheme Iron Proteins
|
Concept
|
Glucose Intolerance
|
Concept
|
beta-Lactam Resistance
|
Concept
|
Wnt1 Protein
|
Concept
|
Fragile X Mental Retardation Protein
|
Concept
|
Protein Transport
|
Concept
|
Long Interspersed Nucleotide Elements
|
Concept
|
Mutation, Missense
|
Concept
|
Feedback, Physiological
|
Concept
|
Multidrug Resistance-Associated Proteins
|
Concept
|
CpG Islands
|
Concept
|
Metabolome
|
Concept
|
Nucleic Acid Denaturation
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Genetic Association Studies
|
Concept
|
GC Rich Sequence
|
Concept
|
Mitochondrial Proteins
|
Concept
|
Drug Resistance, Bacterial
|
Concept
|
Endoplasmic Reticulum Stress
|
Concept
|
Receptors, G-Protein-Coupled
|
Concept
|
Periplasmic Binding Proteins
|
Concept
|
Embryonic Development
|
Concept
|
Chromatin Assembly and Disassembly
|
Concept
|
Histone Code
|
Concept
|
Thymine DNA Glycosylase
|
Concept
|
S-Phase Kinase-Associated Proteins
|
Concept
|
Codon, Initiator
|
Concept
|
Amino Acid Substitution
|
Concept
|
Growth and Development
|
Concept
|
5' Untranslated Regions
|
Concept
|
Cell Cycle Proteins
|
Concept
|
3' Untranslated Regions
|
Concept
|
Amino Acid Motifs
|
Concept
|
Active Transport, Cell Nucleus
|
Concept
|
Base Pairing
|
Concept
|
Catalytic Domain
|
Concept
|
Databases, Genetic
|
Concept
|
Gene Expression Profiling
|
Concept
|
Nucleocytoplasmic Transport Proteins
|
Concept
|
Arabidopsis Proteins
|
Concept
|
Saccharomyces cerevisiae Proteins
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Protein Kinase C
|
Concept
|
Recombinant Proteins
|
Concept
|
Ribosomal Proteins
|
Concept
|
Structure-Activity Relationship
|
Concept
|
Cullin Proteins
|
Concept
|
Host-Pathogen Interactions
|
Concept
|
Inverted Repeat Sequences
|
Concept
|
Ubiquitin-Protein Ligases
|
Concept
|
Photochemical Processes
|
Concept
|
GATA1 Transcription Factor
|
Concept
|
Proteolysis
|
Concept
|
Static Electricity
|
Concept
|
Stereoisomerism
|
Concept
|
Substrate Specificity
|
Concept
|
Reverse Transcription
|
Concept
|
Regulatory Elements, Transcriptional
|
Concept
|
Temperature
|
Concept
|
Protein Interaction Domains and Motifs
|
Concept
|
Down-Regulation
|
Concept
|
Protein Multimerization
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
Circadian Clocks
|
Concept
|
Transfection
|
Concept
|
Wound Healing
|
Concept
|
Friction
|
Concept
|
Molecular Structure
|
Concept
|
Genome, Human
|
Concept
|
Gene Expression Regulation, Enzymologic
|
Concept
|
Gene Expression Regulation, Leukemic
|
Concept
|
Codon, Nonsense
|
Concept
|
Gene Expression Regulation, Plant
|
Concept
|
DNA Methylation
|
Concept
|
Dimerization
|
Concept
|
Scattering, Small Angle
|
Concept
|
Metabolic Networks and Pathways
|
Concept
|
Gene Knockdown Techniques
|
Concept
|
Homeodomain Proteins
|
Concept
|
3' Flanking Region
|
Concept
|
Gene Dosage
|
Concept
|
Cell Lineage
|
Concept
|
Caenorhabditis elegans Proteins
|
Concept
|
Structural Homology, Protein
|
Concept
|
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)
|
Concept
|
Mutant Proteins
|
Concept
|
Gene Fusion
|
Concept
|
RNA Folding
|
Concept
|
Transcriptome
|
Concept
|
Escherichia coli Proteins
|
Concept
|
Genome-Wide Association Study
|
Concept
|
Hep G2 Cells
|
Concept
|
Endoplasmic Reticulum-Associated Degradation
|
Concept
|
RNA Transport
|
Concept
|
Heterogeneous-Nuclear Ribonucleoprotein Group C
|
Concept
|
Tumor Microenvironment
|
Concept
|
Fimbriae Proteins
|
Concept
|
Mutation Rate
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Cell Size
|
Concept
|
Meiotic Prophase I
|
Concept
|
Lipid Metabolism
|
Concept
|
Suppressor of Cytokine Signaling Proteins
|
Concept
|
Myeloid-Lymphoid Leukemia Protein
|
Concept
|
Pore Forming Cytotoxic Proteins
|
Concept
|
Biocatalysis
|
Concept
|
Protein Stability
|
Concept
|
Diet, High-Fat
|
Concept
|
Chloroplast Proteins
|
Concept
|
Wnt Signaling Pathway
|
Concept
|
Base Composition
|
Concept
|
Carrier Proteins
|
Concept
|
Cell Survival
|
Concept
|
Chromatin
|
Concept
|
Crystallization
|
Concept
|
Cyclization
|
Concept
|
DNA, Single-Stranded
|
Concept
|
Drug Resistance, Microbial
|
Concept
|
Enhancer Elements, Genetic
|
Concept
|
Enzyme Stability
|
Concept
|
Epistasis, Genetic
|
Concept
|
Genetic Testing
|
Concept
|
Genotype
|
Concept
|
Glucose
|
Concept
|
Immunity, Innate
|
Concept
|
Kinetics
|
Concept
|
Luminescent Proteins
|
Concept
|
Neoplasm Proteins
|
Concept
|
Nuclear Proteins
|
Concept
|
Organ Specificity
|
Concept
|
Phenotype
|
Concept
|
Phylogeny
|
Concept
|
Signal Transduction
|
Concept
|
Transcriptional Activation
|
Concept
|
Gene Expression Regulation, Bacterial
|
Concept
|
Gene Expression Regulation, Neoplastic
|
Concept
|
Conserved Sequence
|
Concept
|
Regulon
|
Concept
|
Quantitative Trait, Heritable
|
Concept
|
Protein Isoforms
|
Concept
|
Polymorphism, Single Nucleotide
|
Concept
|
RNA Stability
|
Concept
|
Genomics
|
Concept
|
Membrane Transport Proteins
|
Concept
|
Fluorescence Resonance Energy Transfer
|
Concept
|
Protein Array Analysis
|
Concept
|
Quantitative Trait Loci
|
Concept
|
Epigenesis, Genetic
|
Concept
|
Cystine Knot Motifs
|
Concept
|
Protein Kinase Inhibitors
|
Concept
|
Lipogenesis
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Quorum Sensing
|
Concept
|
Ubiquitination
|
Concept
|
Neurogenesis
|
Concept
|
Molecular Dynamics Simulation
|
Concept
|
Nucleotide Motifs
|
Academic Article
|
Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691.
|
Academic Article
|
Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin.
|
Academic Article
|
Intramolecular amide bonds stabilize pili on the surface of bacilli.
|
Academic Article
|
Genome-wide analysis of N1-methyl-adenosine modification in human tRNAs.
|
Academic Article
|
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
|
Academic Article
|
Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA.
|
Academic Article
|
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
|
Academic Article
|
Isopeptide bonds of the major pilin protein BcpA influence pilus structure and bundle formation on the surface of Bacillus cereus.
|
Academic Article
|
A selective fluorescent probe for carbon monoxide imaging in living cells.
|
Academic Article
|
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.
|
Academic Article
|
The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
|
Academic Article
|
Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
|
Academic Article
|
The structure of the human AGT protein bound to DNA and its implications for damage detection.
|
Academic Article
|
A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
|
Academic Article
|
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
|
Academic Article
|
Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus.
|
Academic Article
|
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
|
Academic Article
|
Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein.
|
Academic Article
|
Binding of ReO4(-) with an engineered MoO4(2-)-binding protein: towards a new approach in radiopharmaceutical applications.
|
Academic Article
|
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
|
Academic Article
|
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus.
|
Academic Article
|
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
|
Academic Article
|
FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA.
|
Academic Article
|
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.
|
Academic Article
|
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
|
Academic Article
|
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
|
Academic Article
|
Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging.
|
Academic Article
|
Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
|
Academic Article
|
Unique features of the m6A methylome in Arabidopsis thaliana.
|
Academic Article
|
N6-methyladenosine-dependent regulation of messenger RNA stability.
|
Academic Article
|
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming.
|
Academic Article
|
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
|
Academic Article
|
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
|
Academic Article
|
Gene expression regulation mediated through reversible m6A RNA methylation.
|
Academic Article
|
The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.
|
Academic Article
|
Preparation of DNA containing 5-hydroxymethyl-2'-deoxycytidine modification through phosphoramidites with TBDMS as 5-hydroxymethyl protecting group.
|
Academic Article
|
Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli.
|
Academic Article
|
Molecular mechanisms of two-component system RhpRS regulating type III secretion system in Pseudomonas syringae.
|
Academic Article
|
Sprouts of RNA epigenetics: the discovery of mammalian RNA demethylases.
|
Academic Article
|
Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
|
Academic Article
|
An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe.
|
Academic Article
|
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
|
Academic Article
|
Grand challenge commentary: RNA epigenetics?
|
Academic Article
|
Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.
|
Academic Article
|
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
|
Academic Article
|
Direct functionalization of arenes by primary alcohol sulfonate esters catalyzed by gold(III).
|
Academic Article
|
AirSR, a [2Fe-2S] cluster-containing two-component system, mediates global oxygen sensing and redox signaling in Staphylococcus aureus.
|
Academic Article
|
Dynamic RNA modifications in posttranscriptional regulation.
|
Academic Article
|
Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response.
|
Academic Article
|
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
|
Academic Article
|
Engineering a uranyl-specific binding protein from NikR.
|
Academic Article
|
Aureusimines in Staphylococcus aureus are not involved in virulence.
|
Academic Article
|
Gold(I)-catalyzed intermolecular addition of phenols and carboxylic acids to olefins.
|
Academic Article
|
Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.
|
Academic Article
|
Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+.
|
Academic Article
|
N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions.
|
Academic Article
|
High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing.
|
Academic Article
|
N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas.
|
Academic Article
|
The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression.
|
Academic Article
|
Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
|
Academic Article
|
A highly sensitive and genetically encoded fluorescent reporter for ratiometric monitoring of quinones in living cells.
|
Academic Article
|
Silver-catalyzed intermolecular amination of C--H groups.
|
Academic Article
|
The tightly regulated copper window in yeast.
|
Academic Article
|
TET family proteins: oxidation activity, interacting molecules, and functions in diseases.
|
Academic Article
|
Chemical methods to study protein-nucleic acid interactions.
|
Academic Article
|
Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
|
Academic Article
|
Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans.
|
Academic Article
|
How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases.
|
Academic Article
|
Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states.
|
Academic Article
|
Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.
|
Academic Article
|
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
|
Academic Article
|
A non-heme iron-mediated chemical demethylation in DNA and RNA.
|
Academic Article
|
Efficient gold-catalyzed hydroamination of 1,3-dienes.
|
Academic Article
|
Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions.
|
Academic Article
|
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
|
Academic Article
|
Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
|
Academic Article
|
Cancer: Damage prevention targeted.
|
Academic Article
|
Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
|
Academic Article
|
A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions.
|
Academic Article
|
Nucleic acid modifications with epigenetic significance.
|
Academic Article
|
Mapping recently identified nucleotide variants in the genome and transcriptome.
|
Academic Article
|
Selective recognition of metal ions by metalloregulatory proteins.
|
Academic Article
|
Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage ß-glucosyltransferase.
|
Academic Article
|
Direct reversal of DNA alkylation damage.
|
Academic Article
|
Efficient functionalization of aromatic C-H bonds catalyzed by gold(III) under mild and solvent-free conditions.
|
Academic Article
|
A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine.
|
Academic Article
|
Reversible RNA adenosine methylation in biological regulation.
|
Academic Article
|
Crystal structure of the RNA demethylase ALKBH5 from zebrafish.
|
Academic Article
|
Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
|
Academic Article
|
Nucleic acid oxidation in DNA damage repair and epigenetics.
|
Academic Article
|
Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2.
|
Academic Article
|
An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols.
|
Academic Article
|
Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa.
|
Academic Article
|
In the Staphylococcus aureus two-component system sae, the response regulator SaeR binds to a direct repeat sequence and DNA binding requires phosphorylation by the sensor kinase SaeS.
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Academic Article
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Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.
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Academic Article
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Gold-catalyzed organic transformations.
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Academic Article
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Reading RNA methylation codes through methyl-specific binding proteins.
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Academic Article
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Synthesis of a FTO inhibitor with anticonvulsant activity.
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Academic Article
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Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.
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Academic Article
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Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor.
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Academic Article
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Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
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Academic Article
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Modeling non-heme iron proteins.
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Academic Article
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Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
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Academic Article
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Gold(I)-catalyzed formation of 3-pyrazolines through cycloaddition of diaziridine to alkynes.
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Academic Article
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Nitrene transfer reactions catalyzed by gold complexes.
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Academic Article
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Gold(III)-catalyzed nitrene insertion into aromatic and benzylic C-H groups.
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Academic Article
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Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(a)I.
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Academic Article
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Gold(I)-catalyzed intra- and intermolecular hydroamination of unactivated olefins.
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Academic Article
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A protein engineered to bind uranyl selectively and with femtomolar affinity.
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Academic Article
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Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions.
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Academic Article
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N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency.
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Academic Article
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RNA N6-methyladenosine methylation in post-transcriptional gene expression regulation.
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Academic Article
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Decoding the transcriptome and DNA methylome of human primordial germ cells.
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Academic Article
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High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy.
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Academic Article
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Preparation of Human Nuclear RNA m6A Methyltransferases and Demethylases and Biochemical Characterization of Their Catalytic Activity.
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Academic Article
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Efficient and quantitative high-throughput tRNA sequencing.
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Academic Article
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Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
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Academic Article
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DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes?
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Academic Article
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Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing.
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Academic Article
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RNA epigenetics--chemical messages for posttranscriptional gene regulation.
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Academic Article
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Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability.
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Academic Article
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The dynamic N(1)-methyladenosine methylome in eukaryotic messenger RNA.
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Academic Article
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Nucleic Acid Modifications in Regulation of Gene Expression.
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Academic Article
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Identification of MLL-fusion/MYC?miR-26?TET1 signaling circuit in MLL-rearranged leukemia.
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Academic Article
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Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus.
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Academic Article
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Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing.
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Academic Article
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Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
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Academic Article
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A glance at N(6)-methyladenosine in transcript isoforms.
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Academic Article
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A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
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Academic Article
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Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
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Academic Article
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ALKBH1-Mediated tRNA Demethylation Regulates Translation.
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Academic Article
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Post-transcriptional gene regulation by mRNA modifications.
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Academic Article
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The emerging biology of RNA post-transcriptional modifications.
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Academic Article
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FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.
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Academic Article
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Evolution of transcript modification by N6-methyladenosine in primates.
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Academic Article
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Developing drugs targeting transition metal homeostasis.
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Academic Article
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YTHDF3 facilitates translation and decay of N6-methyladenosine-modified RNA.
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Academic Article
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Chromate Binding and Removal by the Molybdate-Binding Protein ModA.
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Academic Article
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Visualizing a protein's sugars.
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Academic Article
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m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition.
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Academic Article
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DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander?
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Academic Article
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Dynamic RNA Modifications in Gene Expression Regulation.
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Academic Article
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Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning.
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Academic Article
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Chemical Modifications in the Life of an mRNA Transcript.
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Academic Article
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RNA modifications modulate gene expression during development.
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Academic Article
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Epigenetics: Making your mark on DNA.
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Academic Article
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m6A facilitates hippocampus-dependent learning and memory through YTHDF1.
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Academic Article
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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.
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Academic Article
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Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis.
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Academic Article
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia.
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Academic Article
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Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.
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Academic Article
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m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.
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Academic Article
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Single base resolution mapping of 2'-O-methylation sites in human mRNA and in 3' terminal ends of small RNAs.
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Academic Article
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Identifying the m6A Methylome by Affinity Purification and Sequencing.
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Academic Article
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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
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Academic Article
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Phasing Gene Expression: mRNA N6-Methyladenosine Regulates Temporal Progression of Mammalian Cortical Neurogenesis.
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Academic Article
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Epitranscriptomic influences on development and disease.
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Academic Article
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"Gamete On" for m6A: YTHDF2 Exerts Essential Functions in Female Fertility.
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Academic Article
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Publisher Correction: Post-transcriptional gene regulation by mRNA modifications.
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Academic Article
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Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation.
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Academic Article
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Kinetic gating mechanism of DNA damage recognition by Rad4/XPC.
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Grant
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Mechanisms of Pancreatic Cancer Inhibition by SPARC
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Grant
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Mechanism of SPARC peptide FSEC inhibition of angiogenesis in neuroblastoma
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Academic Article
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Special Issue on Regulating the Central Dogma.
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Academic Article
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Inhibition of Copper Transport Induces Apoptosis in Triple-Negative Breast Cancer Cells and Suppresses Tumor Angiogenesis.
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Academic Article
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Regulation of Gene Expression by N6-methyladenosine in Cancer.
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Academic Article
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Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.
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Academic Article
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Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA.
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Academic Article
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METTL14 is essential for ß-cell survival and insulin secretion.
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Academic Article
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Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers.
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Academic Article
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Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites.
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Academic Article
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.
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Academic Article
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Detailed modeling of positive selection improves detection of cancer driver genes.
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Academic Article
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Site-specific m6A editing.
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Academic Article
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Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG.
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Academic Article
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The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs.
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Academic Article
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RADAR: differential analysis of MeRIP-seq data with a random effect model.
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Academic Article
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m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination.
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Academic Article
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N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription.
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Academic Article
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Keth-seq for transcriptome-wide RNA structure mapping.
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Academic Article
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DNA 5-Methylcytosine-Specific Amplification and Sequencing.
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Academic Article
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N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
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Academic Article
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Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ.
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Academic Article
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YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators.
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Academic Article
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REPIC: a database for exploring the N6-methyladenosine methylome.
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Academic Article
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Author Correction: Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ.
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Academic Article
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Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.
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Academic Article
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Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability.
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Academic Article
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A New Model of Spontaneous Colitis in Mice Induced by Deletion of an RNA m6A Methyltransferase Component METTL14 in T Cells.
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Academic Article
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Direct DNA crosslinking with CAP-C uncovers transcription-dependent chromatin organization at high resolution.
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Academic Article
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Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation.
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Academic Article
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation.
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Academic Article
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A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
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Academic Article
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Global Detection of RNA Methylation by Click Degradation.
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Academic Article
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Alterations of 5-hydroxymethylation in circulating cell-free DNA reflect molecular distinctions of subtypes of non-Hodgkin lymphoma.
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Academic Article
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Chromatin and transcriptional regulation by reversible RNA methylation.
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Academic Article
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N6 -methyladenosine modification of lncRNA Pvt1 governs epidermal stemness.
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Academic Article
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Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.
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Academic Article
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Transcriptome-Wide Detection of Internal N7-Methylguanosine.
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Academic Article
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ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
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Academic Article
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Functional analysis of a SOX10 gene mutation associated with Waardenburg syndrome II.
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Academic Article
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Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations.
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Academic Article
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Identification and functional analysis of a novel mutation in the SOX10 gene associated with Waardenburg syndrome type IV.
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Academic Article
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METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
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Academic Article
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HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease.
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Academic Article
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KAS-seq: genome-wide sequencing of single-stranded DNA by N3-kethoxal-assisted labeling.
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Academic Article
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The METTL5-TRMT112 N6-methyladenosine methyltransferase complex regulates mRNA translation via 18S rRNA methylation.
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Academic Article
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Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review.
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Academic Article
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FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development.
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Academic Article
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m7G-quant-seq: Quantitative Detection of RNA Internal N7-Methylguanosine.
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Academic Article
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Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
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Academic Article
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis.
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Academic Article
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Exon architecture controls mRNA m6A suppression and gene expression.
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Academic Article
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The mechanism underlying redundant functions of the YTHDF proteins.
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Academic Article
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m6A-SAC-seq for quantitative whole transcriptome m6A profiling.
|
Concept
|
RNA Recognition Motif Proteins
|
Concept
|
Suppressor of Cytokine Signaling 1 Protein
|
Concept
|
Sequestosome-1 Protein
|
Concept
|
Gene Editing
|
Concept
|
Demethylation
|
Concept
|
Whole Genome Sequencing
|
Concept
|
Myeloid Ecotropic Viral Integration Site 1 Protein
|
Concept
|
Pancreatitis-Associated Proteins
|
Concept
|
Nedd4 Ubiquitin Protein Ligases
|
Concept
|
Poly-ADP-Ribose Binding Proteins
|
Concept
|
Gene Ontology
|
Concept
|
Clustered Regularly Interspaced Short Palindromic Repeats
|
Concept
|
Microbiota
|
Concept
|
Cellular Reprogramming
|
Grant
|
Discovering the epigenetics of RNA modifications
|
Grant
|
RNA methylation and regulatory T cells
|
Grant
|
Interrogation of dynamic RNA modifications in beta cells in type 1 diabetes
|
Grant
|
Recognition and mechanism of N6-methyl adenosine modifications
|
Grant
|
Global Cysteine Modifications in Human Pathogens
|
Grant
|
Predoctoral Training Program in Chemistry and Biology - Renewal 01
|
Grant
|
Direct Oxidative Nucleic Acids Demethylation
|
Grant
|
Base-resolution sequencing of m6A in RNA
|
Grant
|
Direct Oxidative Nucleic Acids Demethylation
|
Academic Article
|
Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
|
Academic Article
|
METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity.
|
Academic Article
|
Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2'-O-methylation.
|
Academic Article
|
YTHDF2 inhibition potentiates radiotherapy antitumor efficacy.
|
Academic Article
|
6mA-METL-9 axis regulates innate immunity in C. elegans.
|
Academic Article
|
Ex vivo gliadin stimulation of intestinal cells.
|
Academic Article
|
RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation.
|
Academic Article
|
Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research.
|
Academic Article
|
BID-seq for transcriptome-wide quantitative sequencing of mRNA pseudouridine at base resolution.
|
Academic Article
|
FMRP phosphorylation modulates neuronal translation through YTHDF1.
|
Academic Article
|
Light-induced LLPS of the CRY2/SPA1/FIO1 complex regulating mRNA methylation and chlorophyll homeostasis in Arabidopsis.
|
Academic Article
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mRNA accessibility within mRNPs as a determinant of gene expression.
|
Academic Article
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Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing.
|
Academic Article
|
Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome.
|
Academic Article
|
5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer.
|
Academic Article
|
Bromodomain-Containing Protein 9 Regulates Signaling Pathways and Reprograms the Epigenome in Immortalized Human Uterine Fibroid Cells.
|
Academic Article
|
5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma.
|
Academic Article
|
m6A RNA methylation regulates mitochondrial function.
|