Item Type | Name |
Concept
|
Actins
|
Concept
|
Adenosine
|
Concept
|
Antigen-Antibody Complex
|
Concept
|
Antigens, Ly
|
Concept
|
Adolescent
|
Concept
|
Adenosine Triphosphatases
|
Concept
|
Sodium-Potassium-Exchanging ATPase
|
Concept
|
Agammaglobulinemia
|
Concept
|
Bone Marrow Cells
|
Concept
|
Alleles
|
Concept
|
Amino Acid Sequence
|
Concept
|
Adult
|
Concept
|
Blood Proteins
|
Concept
|
Antibody Formation
|
Concept
|
Cell Communication
|
Concept
|
Animals
|
Concept
|
Hypoxia
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Anti-Inflammatory Agents
|
Concept
|
Histocompatibility Antigens Class II
|
Concept
|
B-Lymphocytes
|
Concept
|
Base Sequence
|
Concept
|
Cell Differentiation
|
Concept
|
Cell Movement
|
Concept
|
Cell Nucleus
|
Concept
|
Autoantigens
|
Concept
|
DNA Damage
|
Concept
|
Autoantibodies
|
Concept
|
Binding Sites
|
Concept
|
Biological Transport
|
Concept
|
Biopsy
|
Concept
|
Bone Marrow
|
Concept
|
Cell Membrane
|
Concept
|
Cell Division
|
Concept
|
Child
|
Concept
|
Cells
|
Concept
|
Clone Cells
|
Concept
|
Cell Cycle
|
Concept
|
Genes, Immunoglobulin
|
Concept
|
Cicatrix
|
Concept
|
Cross-Linking Reagents
|
Concept
|
DNA-Binding Proteins
|
Concept
|
Cytoplasm
|
Concept
|
Dendritic Cells
|
Concept
|
Immunoglobulin Constant Regions
|
Concept
|
Interleukin-2
|
Concept
|
Interleukins
|
Concept
|
Child, Preschool
|
Concept
|
Enzyme Precursors
|
Concept
|
Cross-Sectional Studies
|
Concept
|
Disease Susceptibility
|
Concept
|
Interferons
|
Concept
|
Endocytosis
|
Concept
|
Enzyme Activation
|
Concept
|
Methyltransferases
|
Concept
|
Gene Expression Regulation
|
Concept
|
Kidney Diseases
|
Concept
|
Killer Cells, Natural
|
Concept
|
Graft Rejection
|
Concept
|
T-Lymphocytes, Helper-Inducer
|
Concept
|
Hematopoietic Stem Cells
|
Concept
|
Immunoglobulin Heavy Chains
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Infant
|
Concept
|
Inflammation
|
Concept
|
Isoenzymes
|
Concept
|
Leukocytes, Mononuclear
|
Concept
|
Lupus Nephritis
|
Concept
|
Membrane Glycoproteins
|
Concept
|
Membrane Proteins
|
Concept
|
Immunoglobulin E
|
Concept
|
Models, Molecular
|
Concept
|
Phospholipids
|
Concept
|
Mammals
|
Concept
|
Mice, Transgenic
|
Concept
|
Immunoglobulin Variable Region
|
Concept
|
Immunohistochemistry
|
Concept
|
Molecular Sequence Data
|
Concept
|
Mice, Inbred BALB C
|
Concept
|
Mice, Inbred C57BL
|
Concept
|
Recombination, Genetic
|
Concept
|
Mutation
|
Concept
|
Myoglobin
|
Concept
|
Peptide Fragments
|
Concept
|
Kidney Tubules
|
Concept
|
Phagocytosis
|
Concept
|
Ligands
|
Concept
|
Liver
|
Concept
|
Mice, Inbred NZB
|
Concept
|
Phosphoproteins
|
Concept
|
Phosphorylation
|
Concept
|
Female
|
Concept
|
Plasma Cells
|
Concept
|
Protein-Tyrosine Kinases
|
Concept
|
Protein Binding
|
Concept
|
Proto-Oncogene Proteins
|
Concept
|
Proteins
|
Concept
|
Transcription Factors
|
Concept
|
Glycine
|
Concept
|
Immunoglobulin G
|
Concept
|
Image Processing, Computer-Assisted
|
Concept
|
Immunoglobulin Joining Region
|
Concept
|
Receptors, Antigen
|
Concept
|
Receptors, Antigen, B-Cell
|
Concept
|
Cohort Studies
|
Concept
|
Sodium
|
Concept
|
RNA
|
Concept
|
RNA Polymerase II
|
Concept
|
Mass Spectrometry
|
Concept
|
Histones
|
Concept
|
Humans
|
Concept
|
Cluster Analysis
|
Concept
|
Time Factors
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Immunoglobulin alpha-Chains
|
Concept
|
Immunoglobulin lambda-Chains
|
Concept
|
Genome
|
Concept
|
Monophenol Monooxygenase
|
Concept
|
United States
|
Concept
|
Immunoglobulin Class Switching
|
Concept
|
Kidney
|
Concept
|
Kidney Failure, Chronic
|
Concept
|
Kidney Glomerulus
|
Concept
|
Phosphotransferases (Alcohol Group Acceptor)
|
Concept
|
Histocompatibility Antigens Class I
|
Concept
|
Biomarkers
|
Concept
|
Lung
|
Concept
|
Male
|
Concept
|
Gene Rearrangement
|
Concept
|
Gene Rearrangement, T-Lymphocyte
|
Concept
|
Trans-Activators
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
Tyrosine
|
Concept
|
Valine
|
Concept
|
Electrophoretic Mobility Shift Assay
|
Concept
|
Up-Regulation
|
Concept
|
Kidney Transplantation
|
Concept
|
B-Lymphocyte Subsets
|
Concept
|
Antigens, CD
|
Concept
|
Lupus Erythematosus, Systemic
|
Concept
|
Microscopy
|
Concept
|
Gene Rearrangement, B-Lymphocyte, Light Chain
|
Concept
|
CD4-Positive T-Lymphocytes
|
Concept
|
Interleukin-7
|
Concept
|
Antibodies, Antiphospholipid
|
Concept
|
Proto-Oncogene Proteins c-myc
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Case-Control Studies
|
Concept
|
T-Lymphocyte Subsets
|
Concept
|
Microscopy, Immunoelectron
|
Concept
|
Sequence Analysis, DNA
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Methylation
|
Concept
|
Phosphatidylinositol Phosphates
|
Concept
|
Treatment Outcome
|
Concept
|
Nephritis, Interstitial
|
Concept
|
Genomic Instability
|
Concept
|
Severe Combined Immunodeficiency
|
Concept
|
RNA-Binding Proteins
|
Concept
|
Point Mutation
|
Concept
|
Antigen Presentation
|
Concept
|
Apoptosis
|
Concept
|
Mice, Knockout
|
Concept
|
CD8-Positive T-Lymphocytes
|
Concept
|
Cell Proliferation
|
Concept
|
Inflammation Mediators
|
Concept
|
Phosphotyrosine
|
Concept
|
ras Proteins
|
Concept
|
Apoptosis Regulatory Proteins
|
Concept
|
Th2 Cells
|
Concept
|
Models, Immunological
|
Concept
|
Proto-Oncogene Proteins c-vav
|
Concept
|
Gene Regulatory Networks
|
Concept
|
MAP Kinase Kinase Kinases
|
Concept
|
Receptors, CXCR4
|
Concept
|
Protein Transport
|
Concept
|
Calcium Signaling
|
Concept
|
Chemokine CXCL12
|
Concept
|
Lymphocyte Count
|
Concept
|
src Homology Domains
|
Concept
|
Inflammasomes
|
Concept
|
Single-Cell Analysis
|
Concept
|
Primary Cell Culture
|
Concept
|
Proteomics
|
Concept
|
Chromatin Assembly and Disassembly
|
Concept
|
Cyclin-Dependent Kinase 4
|
Concept
|
Microarray Analysis
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
Concept
|
COS Cells
|
Concept
|
Microscopy, Confocal
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p16
|
Concept
|
Cell Cycle Proteins
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
Concept
|
Amino Acid Motifs
|
Concept
|
Active Transport, Cell Nucleus
|
Concept
|
Receptors, Interleukin-7
|
Concept
|
Proteome
|
Concept
|
Dendritic Cells, Follicular
|
Concept
|
Gene Expression Profiling
|
Concept
|
STAT3 Transcription Factor
|
Concept
|
Phagosomes
|
Concept
|
Type C Phospholipases
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Mice
|
Concept
|
Endosomes
|
Concept
|
Severity of Illness Index
|
Concept
|
RNA, Messenger
|
Concept
|
Immunoglobulin Light Chains, Surrogate
|
Concept
|
Sulfonamides
|
Concept
|
Ubiquitin-Protein Ligases
|
Concept
|
Immunity, Humoral
|
Concept
|
Interferon Regulatory Factors
|
Concept
|
BH3 Interacting Domain Death Agonist Protein
|
Concept
|
Palatine Tonsil
|
Concept
|
PAX5 Transcription Factor
|
Concept
|
Cyclin D3
|
Concept
|
Laser Capture Microdissection
|
Concept
|
Immunoprecipitation
|
Concept
|
Spleen
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
|
Concept
|
Precursor Cells, B-Lymphoid
|
Concept
|
Immunoblotting
|
Concept
|
Down-Regulation
|
Concept
|
Autoimmunity
|
Concept
|
Histone Acetyltransferases
|
Concept
|
Cyclins
|
Concept
|
Cell Death
|
Concept
|
Phosphatidylinositol 3-Kinase
|
Concept
|
CD79 Antigens
|
Concept
|
Polymerase Chain Reaction
|
Concept
|
Genes, p53
|
Concept
|
Retinoblastoma Protein
|
Concept
|
Proliferating Cell Nuclear Antigen
|
Concept
|
Pre-B Cell Receptors
|
Concept
|
Gene Silencing
|
Concept
|
Imaging, Three-Dimensional
|
Concept
|
Gene Targeting
|
Concept
|
Homeodomain Proteins
|
Concept
|
Ubiquitin
|
Concept
|
Germinal Center
|
Concept
|
Cell Lineage
|
Concept
|
Phosphatidylinositol 3-Kinases
|
Concept
|
Lymphopoiesis
|
Concept
|
JNK Mitogen-Activated Protein Kinases
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
Concept
|
T-Lymphocytes, Regulatory
|
Concept
|
STAT5 Transcription Factor
|
Concept
|
GRB2 Adaptor Protein
|
Concept
|
Basic Helix-Loop-Helix Transcription Factors
|
Concept
|
Cell Cycle Checkpoints
|
Concept
|
Transcriptome
|
Concept
|
Adaptive Immunity
|
Concept
|
RNA, Small Interfering
|
Concept
|
Microscopy, Fluorescence, Multiphoton
|
Concept
|
V(D)J Recombination
|
Concept
|
Cellular Microenvironment
|
Concept
|
Cell Line, Tumor
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Cell Size
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
Concept
|
Toll-Like Receptors
|
Concept
|
Toll-Like Receptor 9
|
Concept
|
Cyclin-Dependent Kinase 6
|
Concept
|
Ikaros Transcription Factor
|
Concept
|
Forkhead Transcription Factors
|
Concept
|
Receptor, Notch1
|
Concept
|
Phospholipase C gamma
|
Concept
|
Lymphoid Progenitor Cells
|
Concept
|
Cyclin D2
|
Concept
|
Allergens
|
Concept
|
Antibodies, Antinuclear
|
Concept
|
Artificial Intelligence
|
Concept
|
Binding, Competitive
|
Concept
|
Calcium
|
Concept
|
Carrier Proteins
|
Concept
|
Cell Line
|
Concept
|
Cell Survival
|
Concept
|
Cells, Cultured
|
Concept
|
Chromatin
|
Concept
|
Crosses, Genetic
|
Concept
|
Enhancer Elements, Genetic
|
Concept
|
Follow-Up Studies
|
Concept
|
Immunoglobulins
|
Concept
|
Immunoglobulin kappa-Chains
|
Concept
|
Immunoglobulin Light Chains
|
Concept
|
Immunologic Memory
|
Concept
|
Lymphocyte Activation
|
Concept
|
Lymphocytes
|
Concept
|
Mice, Mutant Strains
|
Concept
|
Microscopy, Fluorescence
|
Concept
|
Models, Biological
|
Concept
|
Nuclear Proteins
|
Concept
|
Organ Specificity
|
Concept
|
Phenotype
|
Concept
|
Predictive Value of Tests
|
Concept
|
Histone-Lysine N-Methyltransferase
|
Concept
|
Receptors, Antigen, T-Cell
|
Concept
|
Recombinant Fusion Proteins
|
Concept
|
Staining and Labeling
|
Concept
|
T-Lymphocytes
|
Concept
|
Translocation, Genetic
|
Concept
|
Transplantation, Homologous
|
Concept
|
Vimentin
|
Concept
|
Signal Transduction
|
Concept
|
Transcriptional Activation
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
Cytokines
|
Concept
|
Mice, SCID
|
Concept
|
Mice, Inbred NOD
|
Concept
|
Sequence Analysis, RNA
|
Concept
|
Receptors, Platelet-Derived Growth Factor
|
Concept
|
Clonal Anergy
|
Concept
|
DNA Primers
|
Concept
|
Bridged Bicyclo Compounds, Heterocyclic
|
Concept
|
Computational Biology
|
Concept
|
Receptor, Platelet-Derived Growth Factor beta
|
Concept
|
Genomics
|
Concept
|
Quantitative Trait Loci
|
Concept
|
Epigenesis, Genetic
|
Concept
|
Macromolecular Substances
|
Concept
|
Proto-Oncogene Proteins c-akt
|
Concept
|
Proto-Oncogene Proteins c-bcl-6
|
Concept
|
Ubiquitination
|
Concept
|
Young Adult
|
Academic Article
|
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways.
|
Academic Article
|
Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha.
|
Academic Article
|
A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
|
Academic Article
|
Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptor.
|
Academic Article
|
B cell antigen receptor signaling and internalization are mutually exclusive events.
|
Academic Article
|
HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse.
|
Academic Article
|
In situ B cell-mediated immune responses and tubulointerstitial inflammation in human lupus nephritis.
|
Academic Article
|
Subnuclear cyclin D3 compartments and the coordinated regulation of proliferation and immunoglobulin variable gene repression.
|
Academic Article
|
Therapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.
|
Academic Article
|
Regulation of lymphocyte progenitor survival by the proapoptotic activities of Bim and Bid.
|
Academic Article
|
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
|
Academic Article
|
A unique function for cyclin D3 in early B cell development.
|
Academic Article
|
Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor.
|
Academic Article
|
Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.
|
Academic Article
|
Ras orchestrates exit from the cell cycle and light-chain recombination during early B cell development.
|
Academic Article
|
Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression.
|
Academic Article
|
Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring.
|
Academic Article
|
Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation.
|
Academic Article
|
The pre-B cell receptor in B cell development: recent advances, persistent questions and conserved mechanisms.
|
Academic Article
|
PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction.
|
Academic Article
|
Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.
|
Academic Article
|
Vimentin is a dominant target of in situ humoral immunity in human lupus tubulointerstitial nephritis.
|
Academic Article
|
The emerging role of the inflammasome in kidney diseases.
|
Academic Article
|
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling.
|
Academic Article
|
Balancing Proliferation with Ig? Recombination during B-lymphopoiesis.
|
Academic Article
|
RAG Represents a Widespread Threat to the Lymphocyte Genome.
|
Academic Article
|
Histone reader BRWD1 targets and restricts recombination to the Igk locus.
|
Academic Article
|
Self-reactive IgE exacerbates interferon responses associated with autoimmunity.
|
Academic Article
|
EZH2 Regulates the Developmental Timing of Effectors of the Pre-Antigen Receptor Checkpoints.
|
Academic Article
|
BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis.
|
Academic Article
|
Igß ubiquitination activates PI3K signals required for endosomal sorting.
|
Academic Article
|
Regulated Capture of V? Gene Topologically Associating Domains by Transcription Factories.
|
Academic Article
|
Quantifying in situ adaptive immune cell cognate interactions in humans.
|
Academic Article
|
Transcription factories in Ig? allelic choice and diversity.
|
Academic Article
|
CXCR4 signaling directs Igk recombination and the molecular mechanisms of late B lymphopoiesis.
|
Academic Article
|
B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage.
|
Academic Article
|
Kidney tissue hypoxia dictates T cell-mediated injury in murine lupus nephritis.
|
Academic Article
|
Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation.
|
Academic Article
|
Machine Learning to Quantify In Situ Humoral Selection in Human Lupus Tubulointerstitial Inflammation.
|
Academic Article
|
Quantifying the effects of biopsy fixation and staining panel design on automatic instance segmentation of immune cells in human lupus nephritis.
|
Academic Article
|
Compartments and Connections Within the Germinal Center.
|
Academic Article
|
Artificial Intelligence and Cellular Segmentation in Tissue Microscopy Images.
|
Academic Article
|
Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection.
|
Academic Article
|
Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing.
|
Academic Article
|
IRF4 expression by lung dendritic cells drives acute but not Trm cell-dependent memory Th2 responses.
|
Academic Article
|
The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state.
|
Concept
|
Cell Plasticity
|
Concept
|
Machine Learning
|
Concept
|
Forkhead Box Protein O1
|
Concept
|
Enhancer of Zeste Homolog 2 Protein
|
Concept
|
NLR Family, Pyrin Domain-Containing 3 Protein
|
Concept
|
Forkhead Box Protein O3
|
Concept
|
Bcl-2-Like Protein 11
|
Concept
|
Syk Kinase
|
Concept
|
CCCTC-Binding Factor
|
Concept
|
Gene Ontology
|
Concept
|
Polycomb Repressive Complex 2
|
Concept
|
Ataxia Telangiectasia Mutated Proteins
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|
Concept
|
Allografts
|
Academic Article
|
Antigenic responses are hallmarks of fibrotic interstitial lung diseases independent of underlying etiologies.
|
Academic Article
|
Molecular mechanisms insulating proliferation from genotoxic stress in B lymphocytes.
|
Academic Article
|
Lineage-specific 3D genome organization is assembled at multiple scales by IKAROS.
|
Academic Article
|
BRWD1 orchestrates small pre-B?cell chromatin topology by converting static to dynamic cohesin.
|
Academic Article
|
Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data.
|