The University of Chicago Header Logo

Le Shen

Concepts (351)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tight Junctions
28
2022
151
3.870
Why?
Intestinal Mucosa
24
2020
815
2.500
Why?
Hemangioma, Cavernous, Central Nervous System
9
2022
251
1.880
Why?
Epithelium
8
2020
324
1.250
Why?
Epithelial Cells
13
2019
702
1.240
Why?
Occludin
16
2020
66
1.000
Why?
Endocytosis
8
2013
185
0.870
Why?
Membrane Proteins
16
2019
1241
0.870
Why?
Myosin-Light-Chain Kinase
11
2013
41
0.820
Why?
Claudins
8
2022
33
0.750
Why?
Zonula Occludens-1 Protein
12
2020
70
0.730
Why?
KRIT1 Protein
4
2022
62
0.720
Why?
Cell Membrane Permeability
5
2018
119
0.710
Why?
Myosin Type II
3
2018
50
0.650
Why?
rho-Associated Kinases
5
2018
161
0.640
Why?
Signal Transduction
13
2021
3505
0.610
Why?
Apoptosis
6
2021
1737
0.540
Why?
Caco-2 Cells
13
2019
124
0.470
Why?
Animals
43
2025
28061
0.420
Why?
Actins
7
2018
469
0.420
Why?
Apoptosis Regulatory Proteins
5
2020
203
0.400
Why?
Tumor Necrosis Factor-alpha
8
2020
705
0.400
Why?
Phosphoproteins
8
2012
265
0.370
Why?
Mice
27
2025
12133
0.360
Why?
Colon
5
2022
527
0.350
Why?
Paneth Cells
1
2020
10
0.340
Why?
Permeability
9
2015
141
0.330
Why?
Myosin Light Chains
5
2013
29
0.330
Why?
Stem Cell Niche
1
2020
24
0.330
Why?
Colitis
5
2019
253
0.330
Why?
Arginine
1
2020
140
0.330
Why?
Adherens Junctions
1
2008
34
0.300
Why?
Gastric Mucosa
1
2009
68
0.300
Why?
Intestine, Small
1
2020
301
0.290
Why?
Claudin-2
3
2017
10
0.290
Why?
Cadherins
1
2008
165
0.280
Why?
Intestines
4
2020
426
0.280
Why?
Stem Cells
1
2020
382
0.280
Why?
Organoids
2
2022
70
0.270
Why?
MicroRNAs
2
2022
573
0.270
Why?
Endothelium
2
2020
60
0.260
Why?
Caveolae
2
2007
6
0.260
Why?
Phosphorylation
7
2018
1138
0.260
Why?
Enterocolitis
1
2006
13
0.250
Why?
Mice, Inbred C57BL
12
2020
3375
0.250
Why?
Models, Biological
6
2020
1785
0.240
Why?
Humans
39
2025
92331
0.240
Why?
Protein-Arginine N-Methyltransferases
1
2025
22
0.230
Why?
Disease Models, Animal
9
2020
2450
0.230
Why?
Carcinoma, Adenoid Cystic
1
2025
41
0.220
Why?
Povidone-Iodine
1
2024
9
0.220
Why?
Microvilli
2
2018
43
0.220
Why?
Anti-Infective Agents, Local
1
2024
24
0.220
Why?
Salivary Gland Neoplasms
1
2025
77
0.220
Why?
Recombinant Fusion Proteins
1
2005
560
0.210
Why?
Mice, Transgenic
10
2019
1593
0.210
Why?
Actin Cytoskeleton
5
2018
199
0.200
Why?
Dogs
5
2015
705
0.190
Why?
Circulating MicroRNA
1
2022
14
0.190
Why?
Cell Membrane
3
2018
684
0.190
Why?
Cell Line
8
2015
2504
0.180
Why?
Mebendazole
1
2021
8
0.180
Why?
Antinematodal Agents
1
2021
9
0.180
Why?
Sodium-Potassium-Chloride Symporters
2
2012
22
0.180
Why?
Brain
4
2020
2355
0.180
Why?
Claudin-1
4
2011
17
0.180
Why?
MAP Kinase Kinase Kinase 3
1
2020
13
0.170
Why?
Atrioventricular Node
1
2020
36
0.160
Why?
Hemangioma, Cavernous
1
2020
69
0.160
Why?
Plasma Cells
1
2020
86
0.160
Why?
Homeostasis
2
2020
452
0.160
Why?
Molecular Dynamics Simulation
2
2020
272
0.160
Why?
rhoA GTP-Binding Protein
1
2020
86
0.160
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2019
26
0.150
Why?
Autoantigens
1
2020
137
0.150
Why?
Caspase 3
1
2019
163
0.150
Why?
Cisplatin
1
2021
602
0.150
Why?
Autoantibodies
1
2020
278
0.150
Why?
Mutant Proteins
1
2019
97
0.150
Why?
Calcium
3
2019
1183
0.150
Why?
Central Nervous System Neoplasms
1
2019
91
0.150
Why?
Up-Regulation
3
2017
726
0.150
Why?
Ion Channels
1
2020
251
0.150
Why?
Cholesterol
2
2014
361
0.140
Why?
Actomyosin
1
2018
47
0.140
Why?
Mice, Knockout
7
2019
2097
0.140
Why?
T-Box Domain Proteins
1
2019
127
0.140
Why?
Gastrointestinal Tract
1
2019
192
0.140
Why?
Heart Rate
1
2020
502
0.140
Why?
Drug Resistance, Neoplasm
1
2021
621
0.140
Why?
Enterobacteriaceae Infections
1
2017
25
0.140
Why?
Idiopathic Pulmonary Fibrosis
1
2020
206
0.130
Why?
Interleukins
1
2017
133
0.130
Why?
Cytoskeleton
2
2008
202
0.130
Why?
Microtubules
2
2014
130
0.130
Why?
Gastrointestinal Microbiome
2
2020
556
0.130
Why?
Diarrhea
1
2017
180
0.130
Why?
Proto-Oncogene Proteins
1
2019
677
0.120
Why?
Inflammatory Bowel Diseases
5
2013
609
0.120
Why?
X-Ray Microtomography
1
2016
95
0.120
Why?
Cell Proliferation
3
2025
1720
0.120
Why?
Enterovirus B, Human
1
2015
9
0.120
Why?
Enterovirus Infections
1
2015
29
0.120
Why?
CD55 Antigens
1
2015
21
0.120
Why?
Disease Progression
1
2019
1500
0.120
Why?
Protein Transport
4
2014
430
0.120
Why?
Biological Transport
1
2015
410
0.110
Why?
Ovarian Neoplasms
1
2021
787
0.110
Why?
Sterol Regulatory Element Binding Protein 2
1
2014
4
0.110
Why?
Atrial Fibrillation
1
2019
378
0.110
Why?
Transcriptome
1
2019
700
0.110
Why?
Disease Susceptibility
1
2015
208
0.110
Why?
Liver Diseases
1
2015
245
0.110
Why?
Dextran Sulfate
3
2019
69
0.110
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2013
19
0.100
Why?
Microscopy, Fluorescence
4
2010
441
0.100
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2013
43
0.100
Why?
Ethanol
1
2015
262
0.100
Why?
Caveolin 1
2
2010
23
0.100
Why?
Capsaicin
1
2012
45
0.100
Why?
TRPV Cation Channels
1
2012
16
0.100
Why?
Casein Kinase II
1
2012
11
0.100
Why?
Lymphatic Vessels
1
2013
69
0.100
Why?
Chlorides
1
2012
104
0.100
Why?
Real-Time Polymerase Chain Reaction
3
2022
289
0.090
Why?
Endothelial Cells
3
2020
471
0.090
Why?
Cell Line, Tumor
4
2025
2662
0.090
Why?
Bridged Bicyclo Compounds, Heterocyclic
3
2012
97
0.090
Why?
Xenograft Model Antitumor Assays
2
2025
501
0.090
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2012
108
0.090
Why?
Lung
2
2020
1337
0.090
Why?
Wound Healing
2
2021
371
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
3
2022
887
0.090
Why?
Protein Kinase C
2
2008
266
0.090
Why?
Protein Interaction Domains and Motifs
1
2011
88
0.090
Why?
Immunity, Innate
2
2017
441
0.080
Why?
Antineoplastic Agents
1
2021
2365
0.080
Why?
Interferon-gamma
3
2008
455
0.080
Why?
T-Lymphocyte Subsets
1
2012
283
0.080
Why?
Dynamin II
2
2011
15
0.080
Why?
Myosin Heavy Chains
2
2020
91
0.080
Why?
Interleukin-13
1
2010
41
0.080
Why?
Clathrin
1
2009
32
0.080
Why?
Tetradecanoylphorbol Acetate
1
2009
137
0.080
Why?
Protein Binding
5
2013
1513
0.080
Why?
Wnt Signaling Pathway
1
2020
103
0.080
Why?
cdc42 GTP-Binding Protein
1
2008
13
0.080
Why?
Microscopy, Electron
2
2022
509
0.070
Why?
Immunity, Mucosal
1
2009
70
0.070
Why?
Fluorescence Recovery After Photobleaching
1
2008
13
0.070
Why?
Immunohistochemistry
4
2015
1804
0.070
Why?
Sodium-Hydrogen Exchangers
1
2008
78
0.070
Why?
Diffusion
1
2008
91
0.070
Why?
Thiazolidines
2
2005
18
0.070
Why?
Organ Specificity
1
2009
282
0.070
Why?
Intracellular Signaling Peptides and Proteins
3
2018
389
0.070
Why?
DNA Primers
2
2022
543
0.070
Why?
Multiprotein Complexes
1
2008
103
0.070
Why?
Cell Polarity
1
2008
117
0.070
Why?
Acute Disease
2
2020
855
0.070
Why?
Tumor Necrosis Factor Ligand Superfamily Member 14
1
2007
14
0.070
Why?
Thiazoles
2
2005
128
0.070
Why?
Time Factors
4
2024
5430
0.070
Why?
Bacterial Infections
1
2009
185
0.070
Why?
Serotonin
1
2008
219
0.070
Why?
Myocytes, Cardiac
2
2020
317
0.070
Why?
Claudin-4
2
2020
8
0.060
Why?
Enzyme Induction
1
2006
87
0.060
Why?
Cells, Cultured
3
2019
2902
0.060
Why?
Chronic Disease
2
2020
966
0.060
Why?
RNA, Small Interfering
3
2014
560
0.060
Why?
Cytokines
4
2017
842
0.060
Why?
Intestinal Absorption
1
2006
125
0.060
Why?
Clathrin-Coated Vesicles
1
2005
10
0.060
Why?
Porins
1
2005
21
0.060
Why?
T-Lymphocytes
2
2018
1279
0.060
Why?
Adhesins, Bacterial
1
2005
36
0.060
Why?
Lectins
1
2005
86
0.060
Why?
Genes, Reporter
1
2005
278
0.060
Why?
Ion Transport
2
2018
86
0.060
Why?
Drug Storage
1
2024
4
0.060
Why?
Ophthalmic Solutions
1
2024
17
0.060
Why?
Computational Biology
1
2008
568
0.060
Why?
Drosophila
1
2008
526
0.060
Why?
Eye Infections, Bacterial
1
2024
17
0.060
Why?
Triglycerides
2
2015
234
0.050
Why?
Female
7
2025
47895
0.050
Why?
Microbial Sensitivity Tests
1
2024
150
0.050
Why?
Drosophila Proteins
1
2008
513
0.050
Why?
Computer Simulation
1
2008
1112
0.050
Why?
Cell Movement
2
2021
801
0.050
Why?
Pseudomonas aeruginosa
1
2005
207
0.050
Why?
Reproducibility of Results
2
2022
2793
0.050
Why?
Tissue Distribution
3
2010
294
0.050
Why?
Freeze Fracturing
1
2022
12
0.050
Why?
Phenotype
2
2020
2503
0.050
Why?
Receptor Aggregation
1
2002
3
0.050
Why?
beta-Cyclodextrins
1
2002
9
0.050
Why?
Ligands
2
2019
457
0.050
Why?
Binding Sites
2
2018
1131
0.050
Why?
Gene Knockdown Techniques
2
2013
250
0.050
Why?
fas Receptor
1
2002
77
0.050
Why?
Blotting, Western
2
2014
793
0.050
Why?
Tumor Stem Cell Assay
1
2021
40
0.050
Why?
Drug Discovery
1
2022
110
0.050
Why?
Solute Carrier Family 12, Member 2
2
2012
16
0.050
Why?
Male
6
2020
43923
0.050
Why?
Drug Repositioning
1
2021
25
0.050
Why?
Green Fluorescent Proteins
2
2012
307
0.040
Why?
Cyclic N-Oxides
1
2020
33
0.040
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2020
36
0.040
Why?
Protein Structure, Tertiary
2
2013
740
0.040
Why?
Bayes Theorem
1
2022
391
0.040
Why?
Cholecalciferol
1
2020
35
0.040
Why?
Vimentin
1
2020
49
0.040
Why?
Bacteria
1
2024
500
0.040
Why?
Spin Labels
1
2020
107
0.040
Why?
Tight Junction Proteins
1
2020
14
0.040
Why?
Tubulin
1
2020
60
0.040
Why?
Alveolar Epithelial Cells
1
2020
18
0.040
Why?
Carrier Proteins
2
2019
679
0.040
Why?
Liver
2
2015
1225
0.040
Why?
Adaptor Proteins, Signal Transducing
1
2002
316
0.040
Why?
Trinitrobenzenesulfonic Acid
1
2019
16
0.040
Why?
Connexin 43
1
2020
94
0.040
Why?
Astrocytes
1
2020
143
0.040
Why?
Metagenomics
1
2020
95
0.040
Why?
Respiratory Mucosa
1
2020
88
0.040
Why?
Mice, Nude
1
2021
825
0.040
Why?
DNA, Bacterial
1
2020
247
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2025
1308
0.040
Why?
Cations, Divalent
1
2019
39
0.040
Why?
RNA, Ribosomal, 16S
1
2020
259
0.040
Why?
Cost-Benefit Analysis
1
2022
488
0.040
Why?
Potassium Channels, Voltage-Gated
1
2020
125
0.040
Why?
Toll-Like Receptor 4
1
2019
91
0.040
Why?
Middle Aged
4
2020
27043
0.040
Why?
Gene Deletion
1
2020
354
0.040
Why?
High-Throughput Nucleotide Sequencing
1
2022
499
0.040
Why?
Lipopolysaccharides
1
2020
301
0.040
Why?
Zonula Occludens-2 Protein
1
2018
11
0.040
Why?
Connexins
1
2020
202
0.040
Why?
Biological Transport, Active
1
2018
102
0.040
Why?
Hemorrhage
1
2020
290
0.040
Why?
Feces
1
2020
349
0.040
Why?
Dynamins
1
2018
50
0.040
Why?
HEK293 Cells
1
2020
667
0.040
Why?
Dexamethasone
1
2019
347
0.040
Why?
Enzyme Activation
2
2010
695
0.040
Why?
Citrobacter rodentium
1
2017
14
0.030
Why?
Iron
1
2018
175
0.030
Why?
Pilot Projects
1
2020
902
0.030
Why?
Protein Multimerization
1
2018
184
0.030
Why?
Microfilament Proteins
1
2018
212
0.030
Why?
Gene Regulatory Networks
1
2019
315
0.030
Why?
Caspases
2
2011
157
0.030
Why?
Histological Techniques
1
2016
36
0.030
Why?
Cerebellum
1
2018
251
0.030
Why?
Aged
3
2020
19951
0.030
Why?
Iodine
1
2016
44
0.030
Why?
Inulin
1
2015
17
0.030
Why?
Sodium
1
2017
335
0.030
Why?
Recombinant Proteins
2
2010
1016
0.030
Why?
Water
1
2017
292
0.030
Why?
Organ Size
1
2016
374
0.030
Why?
Case-Control Studies
1
2019
1900
0.030
Why?
Patch-Clamp Techniques
1
2015
397
0.030
Why?
Dynactin Complex
1
2014
2
0.030
Why?
Observer Variation
1
2016
612
0.030
Why?
Benzyl Compounds
1
2014
7
0.030
Why?
Nocodazole
1
2014
18
0.030
Why?
Dyneins
1
2014
14
0.030
Why?
Madin Darby Canine Kidney Cells
1
2014
21
0.030
Why?
Immunoblotting
1
2015
277
0.030
Why?
Tubulin Modulators
1
2014
23
0.030
Why?
Adult
3
2020
27540
0.030
Why?
Fluorescent Antibody Technique
1
2015
323
0.030
Why?
Lymphocyte Activation
2
2009
785
0.030
Why?
Brain Neoplasms
1
2020
807
0.030
Why?
Cholesterol, VLDL
1
2014
14
0.030
Why?
Adenine
1
2014
89
0.030
Why?
Jejunum
1
2014
80
0.030
Why?
Golgi Apparatus
1
2014
117
0.030
Why?
Biomarkers
1
2020
1847
0.030
Why?
B-Lymphocytes
1
2018
753
0.030
Why?
Microtubule-Associated Proteins
1
2014
184
0.030
Why?
RNA Interference
1
2014
381
0.030
Why?
Colforsin
1
2012
74
0.020
Why?
Diterpenes
1
2012
22
0.020
Why?
Biotinylation
1
2012
41
0.020
Why?
Crohn Disease
1
2019
772
0.020
Why?
Adoptive Transfer
1
2013
173
0.020
Why?
Acrylamides
1
2012
35
0.020
Why?
Electric Conductivity
1
2012
145
0.020
Why?
Sequence Deletion
1
2013
211
0.020
Why?
Cholesterol, LDL
1
2014
237
0.020
Why?
Colitis, Ulcerative
1
2019
775
0.020
Why?
Weight Loss
1
2013
239
0.020
Why?
Contrast Media
1
2016
1076
0.020
Why?
Dopamine
1
2012
274
0.020
Why?
Luminescent Proteins
1
2011
142
0.020
Why?
Electrophysiology
1
2011
402
0.020
Why?
MARVEL Domain Containing 2 Protein
1
2010
2
0.020
Why?
Microscopy, Immunoelectron
1
2010
29
0.020
Why?
Subcellular Fractions
1
2010
95
0.020
Why?
Tissue Culture Techniques
1
2010
81
0.020
Why?
Plasmids
1
2010
288
0.020
Why?
Sequence Homology, Amino Acid
1
2010
419
0.020
Why?
Egtazic Acid
1
2008
33
0.020
Why?
Dose-Response Relationship, Drug
1
2012
1938
0.020
Why?
Protein Kinase C-delta
1
2008
29
0.020
Why?
Carbazoles
1
2008
31
0.020
Why?
Protein Kinase C-alpha
1
2008
29
0.020
Why?
Mucous Membrane
1
2008
84
0.020
Why?
Major Histocompatibility Complex
1
2008
85
0.020
Why?
Microscopy, Electron, Transmission
1
2008
136
0.020
Why?
Young Adult
1
2020
6629
0.020
Why?
Microscopy, Confocal
1
2008
282
0.020
Why?
Adolescent
1
2020
9495
0.020
Why?
Lymphotoxin beta Receptor
1
2007
28
0.020
Why?
Cardiac Myosins
1
2007
19
0.020
Why?
Mutation
1
2018
4212
0.020
Why?
Glucose
1
2009
683
0.020
Why?
Amino Acid Sequence
1
2010
2075
0.020
Why?
Base Sequence
1
2010
2324
0.020
Why?
Pyocyanine
1
2005
12
0.020
Why?
CD4-Positive T-Lymphocytes
1
2008
461
0.010
Why?
Molecular Sequence Data
1
2010
3023
0.010
Why?
Computer Systems
1
2005
79
0.010
Why?
Virulence
1
2005
277
0.010
Why?
Kidney
1
2009
1144
0.010
Why?
Phylogeny
1
2010
1230
0.010
Why?
RNA, Messenger
1
2010
2037
0.010
Why?
Escherichia coli Infections
1
2004
35
0.010
Why?
Severity of Illness Index
1
2008
1920
0.010
Why?
Aged, 80 and over
1
2013
6917
0.010
Why?
Nystatin
1
2002
2
0.010
Why?
Filipin
1
2002
2
0.010
Why?
Fas-Associated Death Domain Protein
1
2002
7
0.010
Why?
Cyclodextrins
1
2002
7
0.010
Why?
Ionophores
1
2002
14
0.010
Why?
Amino Acid Chloromethyl Ketones
1
2002
25
0.010
Why?
Caspase 8
1
2002
35
0.010
Why?
Caspase 9
1
2002
48
0.010
Why?
Caspase Inhibitors
1
2002
33
0.010
Why?
Membrane Microdomains
1
2002
54
0.010
Why?
Membrane Potentials
1
2002
436
0.010
Why?
Fluorescent Dyes
1
2002
260
0.010
Why?
Lymphocytes
1
2002
476
0.010
Why?
Mitochondria
1
2002
595
0.010
Why?
Anti-Bacterial Agents
1
2002
808
0.010
Why?
Shen's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (351)
Explore
_
Co-Authors (57)
Explore
_
Similar People (60)
Explore
_
Same Department Expand Description
Explore
_
Physical Neighbors
_