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Le Shen

Concepts (372)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tight Junctions
28
2022
154
3.660
Why?
Intestinal Mucosa
24
2020
825
2.390
Why?
Hemangioma, Cavernous, Central Nervous System
9
2022
257
1.780
Why?
Epithelium
8
2020
314
1.190
Why?
Epithelial Cells
13
2019
700
1.180
Why?
Occludin
16
2020
66
0.950
Why?
Endocytosis
8
2013
184
0.830
Why?
Membrane Proteins
16
2019
1260
0.820
Why?
Myosin-Light-Chain Kinase
11
2013
38
0.780
Why?
Claudins
8
2022
34
0.710
Why?
Zonula Occludens-1 Protein
12
2020
70
0.690
Why?
KRIT1 Protein
4
2022
61
0.680
Why?
Cell Membrane Permeability
5
2018
121
0.670
Why?
Myosin Type II
3
2018
50
0.610
Why?
rho-Associated Kinases
5
2018
161
0.610
Why?
Signal Transduction
13
2021
3497
0.580
Why?
Apoptosis
6
2021
1719
0.520
Why?
Colon
6
2025
540
0.510
Why?
Caco-2 Cells
13
2019
125
0.440
Why?
Animals
43
2025
27973
0.400
Why?
Actins
7
2018
467
0.400
Why?
Apoptosis Regulatory Proteins
5
2020
201
0.380
Why?
Tumor Necrosis Factor-alpha
8
2020
688
0.380
Why?
Phosphoproteins
8
2012
258
0.350
Why?
Mice
27
2025
12230
0.340
Why?
Paneth Cells
1
2020
10
0.320
Why?
Permeability
9
2015
143
0.320
Why?
Myosin Light Chains
5
2013
25
0.320
Why?
Stem Cell Niche
1
2020
23
0.320
Why?
Colitis
5
2019
260
0.310
Why?
Arginine
1
2020
140
0.310
Why?
Gastric Mucosa
1
2009
71
0.280
Why?
Adherens Junctions
1
2008
34
0.280
Why?
Intestine, Small
1
2020
311
0.280
Why?
Claudin-2
3
2017
10
0.270
Why?
Intestines
4
2020
433
0.270
Why?
Stem Cells
1
2020
386
0.260
Why?
Cadherins
1
2008
180
0.260
Why?
MicroRNAs
2
2022
581
0.260
Why?
Inflammatory Bowel Diseases
6
2025
647
0.250
Why?
Drug Resistance, Neoplasm
2
2021
636
0.250
Why?
Organoids
2
2022
76
0.250
Why?
Transcriptome
2
2025
762
0.250
Why?
Endothelium
2
2020
59
0.250
Why?
Phosphorylation
7
2018
1129
0.240
Why?
Humans
41
2025
93138
0.240
Why?
Caveolae
2
2007
6
0.240
Why?
Enterocolitis
1
2006
13
0.240
Why?
Mice, Inbred C57BL
12
2020
3431
0.240
Why?
Models, Biological
6
2020
1768
0.230
Why?
Protein-Arginine N-Methyltransferases
1
2025
22
0.220
Why?
Disease Models, Animal
9
2020
2479
0.220
Why?
Carcinoma, Adenoid Cystic
1
2025
43
0.210
Why?
Povidone-Iodine
1
2024
9
0.210
Why?
Microvilli
2
2018
44
0.210
Why?
Anti-Infective Agents, Local
1
2024
24
0.210
Why?
Colonic Pouches
1
2025
97
0.210
Why?
Proctocolectomy, Restorative
1
2025
115
0.210
Why?
Salivary Gland Neoplasms
1
2025
81
0.200
Why?
Recombinant Fusion Proteins
1
2005
550
0.200
Why?
Mice, Transgenic
10
2019
1581
0.200
Why?
Actin Cytoskeleton
5
2018
196
0.190
Why?
Dogs
5
2015
632
0.180
Why?
Circulating MicroRNA
1
2022
14
0.180
Why?
Cell Membrane
3
2018
661
0.180
Why?
Cell Line
8
2015
2458
0.180
Why?
Mebendazole
1
2021
8
0.170
Why?
Antinematodal Agents
1
2021
9
0.170
Why?
Sodium-Potassium-Chloride Symporters
2
2012
22
0.170
Why?
Brain
4
2020
2337
0.170
Why?
Claudin-1
4
2011
17
0.170
Why?
Eukaryotic Initiation Factor-4A
1
2020
3
0.160
Why?
Sterols
1
2020
19
0.160
Why?
5' Untranslated Regions
1
2020
51
0.160
Why?
Colitis, Ulcerative
2
2025
800
0.160
Why?
MAP Kinase Kinase Kinase 3
1
2020
13
0.160
Why?
Atrioventricular Node
1
2020
37
0.160
Why?
Hemangioma, Cavernous
1
2020
66
0.150
Why?
Plasma Cells
1
2020
84
0.150
Why?
Homeostasis
2
2020
459
0.150
Why?
rhoA GTP-Binding Protein
1
2020
87
0.150
Why?
Molecular Dynamics Simulation
2
2020
304
0.150
Why?
Cisplatin
1
2021
567
0.150
Why?
Autoantigens
1
2020
138
0.150
Why?
Caspase 3
1
2019
161
0.150
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2019
29
0.150
Why?
Autoantibodies
1
2020
276
0.140
Why?
Mutant Proteins
1
2019
98
0.140
Why?
Calcium
3
2019
1173
0.140
Why?
Up-Regulation
3
2017
727
0.140
Why?
Central Nervous System Neoplasms
1
2019
98
0.140
Why?
Ion Channels
1
2020
256
0.140
Why?
Cholesterol
2
2014
364
0.140
Why?
Mice, Knockout
7
2019
2121
0.140
Why?
Actomyosin
1
2018
47
0.140
Why?
T-Box Domain Proteins
1
2019
127
0.130
Why?
Gastrointestinal Tract
1
2019
196
0.130
Why?
ATP-Binding Cassette Transporters
1
2018
140
0.130
Why?
Heart Rate
1
2020
507
0.130
Why?
Enterobacteriaceae Infections
1
2017
24
0.130
Why?
Idiopathic Pulmonary Fibrosis
1
2020
210
0.130
Why?
Interleukins
1
2017
133
0.120
Why?
Cytoskeleton
2
2008
198
0.120
Why?
Diarrhea
1
2017
176
0.120
Why?
Microtubules
2
2014
134
0.120
Why?
Gastrointestinal Microbiome
2
2020
595
0.120
Why?
Proto-Oncogene Proteins
1
2019
663
0.120
Why?
Cell Line, Tumor
5
2025
2757
0.120
Why?
Mycobacterium tuberculosis
1
2018
208
0.120
Why?
X-Ray Microtomography
1
2016
102
0.120
Why?
Cell Proliferation
3
2025
1732
0.120
Why?
Enterovirus B, Human
1
2015
9
0.110
Why?
Enterovirus Infections
1
2015
25
0.110
Why?
CD55 Antigens
1
2015
21
0.110
Why?
Disease Progression
1
2019
1529
0.110
Why?
Protein Transport
4
2014
438
0.110
Why?
Biological Transport
1
2015
398
0.110
Why?
Ovarian Neoplasms
1
2021
795
0.110
Why?
Sterol Regulatory Element Binding Protein 2
1
2014
5
0.100
Why?
Atrial Fibrillation
1
2019
418
0.100
Why?
Disease Susceptibility
1
2015
220
0.100
Why?
Protein Binding
6
2018
1526
0.100
Why?
Liver Diseases
1
2015
243
0.100
Why?
Dextran Sulfate
3
2019
70
0.100
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2013
20
0.100
Why?
Microscopy, Fluorescence
4
2010
435
0.100
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2013
40
0.100
Why?
Ethanol
1
2015
273
0.100
Why?
Caveolin 1
2
2010
24
0.090
Why?
Capsaicin
1
2012
43
0.090
Why?
TRPV Cation Channels
1
2012
16
0.090
Why?
Casein Kinase II
1
2012
11
0.090
Why?
Chlorides
1
2012
100
0.090
Why?
Lymphatic Vessels
1
2013
70
0.090
Why?
Endothelial Cells
3
2020
477
0.090
Why?
Real-Time Polymerase Chain Reaction
3
2022
296
0.090
Why?
Bridged Bicyclo Compounds, Heterocyclic
3
2012
98
0.090
Why?
Xenograft Model Antitumor Assays
2
2025
526
0.090
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2012
111
0.090
Why?
Lung
2
2020
1359
0.080
Why?
Reverse Transcriptase Polymerase Chain Reaction
3
2022
885
0.080
Why?
Wound Healing
2
2021
372
0.080
Why?
Protein Kinase C
2
2008
260
0.080
Why?
Protein Interaction Domains and Motifs
1
2011
85
0.080
Why?
Antineoplastic Agents
1
2021
2301
0.080
Why?
Immunity, Innate
2
2017
463
0.080
Why?
Interferon-gamma
3
2008
459
0.080
Why?
T-Lymphocyte Subsets
1
2012
288
0.080
Why?
Dynamin II
2
2011
15
0.080
Why?
Myosin Heavy Chains
2
2020
86
0.080
Why?
Interleukin-13
1
2010
42
0.080
Why?
Clathrin
1
2009
31
0.080
Why?
Tetradecanoylphorbol Acetate
1
2009
121
0.080
Why?
Wnt Signaling Pathway
1
2020
103
0.070
Why?
Binding Sites
3
2018
1126
0.070
Why?
cdc42 GTP-Binding Protein
1
2008
12
0.070
Why?
Microscopy, Electron
2
2022
429
0.070
Why?
Immunity, Mucosal
1
2009
71
0.070
Why?
Fluorescence Recovery After Photobleaching
1
2008
12
0.070
Why?
Immunohistochemistry
4
2015
1786
0.070
Why?
Sodium-Hydrogen Exchangers
1
2008
78
0.070
Why?
Thiazolidines
2
2005
15
0.070
Why?
Case-Control Studies
2
2025
1926
0.070
Why?
Diffusion
1
2008
94
0.070
Why?
Intracellular Signaling Peptides and Proteins
3
2018
392
0.070
Why?
DNA Primers
2
2022
528
0.070
Why?
Organ Specificity
1
2009
279
0.070
Why?
Multiprotein Complexes
1
2008
106
0.070
Why?
Cell Polarity
1
2008
118
0.060
Why?
Acute Disease
2
2020
838
0.060
Why?
Time Factors
4
2024
5380
0.060
Why?
Thiazoles
2
2005
124
0.060
Why?
Bacterial Infections
1
2009
178
0.060
Why?
Tumor Necrosis Factor Ligand Superfamily Member 14
1
2007
14
0.060
Why?
Serotonin
1
2008
209
0.060
Why?
Female
8
2025
48547
0.060
Why?
Myocytes, Cardiac
2
2020
312
0.060
Why?
Claudin-4
2
2020
8
0.060
Why?
Cells, Cultured
3
2019
2827
0.060
Why?
Chronic Disease
2
2020
941
0.060
Why?
Enzyme Induction
1
2006
83
0.060
Why?
RNA, Small Interfering
3
2014
556
0.060
Why?
Crohn Disease
2
2025
808
0.060
Why?
Cytokines
4
2017
862
0.060
Why?
Intestinal Absorption
1
2006
125
0.060
Why?
T-Lymphocytes
2
2018
1276
0.060
Why?
Clathrin-Coated Vesicles
1
2005
10
0.060
Why?
Porins
1
2005
24
0.060
Why?
Adhesins, Bacterial
1
2005
36
0.060
Why?
Lectins
1
2005
82
0.060
Why?
Male
7
2025
44360
0.050
Why?
Genes, Reporter
1
2005
275
0.050
Why?
Ion Transport
2
2018
82
0.050
Why?
Drug Storage
1
2024
4
0.050
Why?
Ophthalmic Solutions
1
2024
14
0.050
Why?
Computational Biology
1
2008
581
0.050
Why?
Eye Infections, Bacterial
1
2024
11
0.050
Why?
Triglycerides
2
2015
231
0.050
Why?
Drosophila
1
2008
539
0.050
Why?
Microbial Sensitivity Tests
1
2024
144
0.050
Why?
Middle Aged
5
2025
27539
0.050
Why?
Colectomy
1
2025
192
0.050
Why?
Drosophila Proteins
1
2008
521
0.050
Why?
Computer Simulation
1
2008
1120
0.050
Why?
Pseudomonas aeruginosa
1
2005
199
0.050
Why?
Cell Movement
2
2021
804
0.050
Why?
Reproducibility of Results
2
2022
2705
0.050
Why?
Single-Cell Analysis
1
2025
200
0.050
Why?
Tissue Distribution
3
2010
287
0.050
Why?
Freeze Fracturing
1
2022
11
0.050
Why?
Phenotype
2
2020
2545
0.050
Why?
Receptor Aggregation
1
2002
3
0.040
Why?
beta-Cyclodextrins
1
2002
10
0.040
Why?
Gene Knockdown Techniques
2
2013
254
0.040
Why?
Ligands
2
2019
476
0.040
Why?
Blotting, Western
2
2014
774
0.040
Why?
fas Receptor
1
2002
73
0.040
Why?
Drug Discovery
1
2022
113
0.040
Why?
Tumor Stem Cell Assay
1
2021
41
0.040
Why?
Solute Carrier Family 12, Member 2
2
2012
16
0.040
Why?
Drug Repositioning
1
2021
26
0.040
Why?
Adult
4
2025
27850
0.040
Why?
Young Adult
2
2025
6922
0.040
Why?
Green Fluorescent Proteins
2
2012
309
0.040
Why?
Protein Structure, Tertiary
2
2013
726
0.040
Why?
Cyclic N-Oxides
1
2020
32
0.040
Why?
Bayes Theorem
1
2022
403
0.040
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2020
36
0.040
Why?
Cholecalciferol
1
2020
35
0.040
Why?
Vimentin
1
2020
47
0.040
Why?
Bacteria
1
2024
508
0.040
Why?
Spin Labels
1
2020
105
0.040
Why?
Carrier Proteins
2
2019
660
0.040
Why?
Tight Junction Proteins
1
2020
14
0.040
Why?
Adaptor Proteins, Signal Transducing
1
2002
304
0.040
Why?
Tubulin
1
2020
61
0.040
Why?
Liver
2
2015
1206
0.040
Why?
Alveolar Epithelial Cells
1
2020
18
0.040
Why?
Ribosomes
1
2020
102
0.040
Why?
CRISPR-Cas Systems
1
2020
98
0.040
Why?
Connexin 43
1
2020
94
0.040
Why?
Trinitrobenzenesulfonic Acid
1
2019
16
0.040
Why?
Astrocytes
1
2020
136
0.040
Why?
Mice, Nude
1
2021
823
0.040
Why?
Metagenomics
1
2020
101
0.040
Why?
Potassium Channels, Voltage-Gated
1
2020
111
0.040
Why?
Gene Expression Profiling
1
2025
1517
0.040
Why?
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
1
2020
175
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2025
1339
0.040
Why?
Respiratory Mucosa
1
2020
90
0.040
Why?
DNA, Bacterial
1
2020
232
0.040
Why?
RNA, Ribosomal, 16S
1
2020
260
0.040
Why?
Cations, Divalent
1
2019
34
0.040
Why?
Cost-Benefit Analysis
1
2022
494
0.040
Why?
Gene Deletion
1
2020
351
0.040
Why?
Toll-Like Receptor 4
1
2019
91
0.040
Why?
Lipopolysaccharides
1
2020
300
0.040
Why?
High-Throughput Nucleotide Sequencing
1
2022
538
0.040
Why?
Zonula Occludens-2 Protein
1
2018
11
0.040
Why?
Biological Transport, Active
1
2018
98
0.040
Why?
Connexins
1
2020
206
0.040
Why?
Phosphothreonine
1
2018
4
0.040
Why?
Hemorrhage
1
2020
289
0.030
Why?
Feces
1
2020
360
0.030
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2018
65
0.030
Why?
Dynamins
1
2018
48
0.030
Why?
Dexamethasone
1
2019
311
0.030
Why?
Enzyme Activation
2
2010
672
0.030
Why?
HEK293 Cells
1
2020
696
0.030
Why?
Mutation
2
2020
4265
0.030
Why?
Iron
1
2018
173
0.030
Why?
Citrobacter rodentium
1
2017
14
0.030
Why?
Cytoplasm
1
2018
275
0.030
Why?
Pilot Projects
1
2020
913
0.030
Why?
Protein Structure, Secondary
1
2018
337
0.030
Why?
Protein Multimerization
1
2018
190
0.030
Why?
Microfilament Proteins
1
2018
208
0.030
Why?
Gene Regulatory Networks
1
2019
317
0.030
Why?
Caspases
2
2011
151
0.030
Why?
Crystallography, X-Ray
1
2018
520
0.030
Why?
Cerebellum
1
2018
247
0.030
Why?
Histological Techniques
1
2016
33
0.030
Why?
Iodine
1
2016
43
0.030
Why?
Aged
3
2020
20398
0.030
Why?
Inulin
1
2015
17
0.030
Why?
Sodium
1
2017
328
0.030
Why?
Recombinant Proteins
2
2010
981
0.030
Why?
Water
1
2017
306
0.030
Why?
Organ Size
1
2016
360
0.030
Why?
Observer Variation
1
2016
570
0.030
Why?
Patch-Clamp Techniques
1
2015
378
0.030
Why?
Risk Factors
1
2025
5901
0.030
Why?
Dynactin Complex
1
2014
2
0.030
Why?
Benzyl Compounds
1
2014
7
0.030
Why?
Nocodazole
1
2014
18
0.030
Why?
Dyneins
1
2014
14
0.030
Why?
Immunoblotting
1
2015
273
0.030
Why?
Madin Darby Canine Kidney Cells
1
2014
23
0.030
Why?
Tubulin Modulators
1
2014
23
0.030
Why?
Fluorescent Antibody Technique
1
2015
306
0.030
Why?
Brain Neoplasms
1
2020
810
0.030
Why?
Lymphocyte Activation
2
2009
798
0.030
Why?
Cholesterol, VLDL
1
2014
14
0.030
Why?
Models, Molecular
1
2018
1353
0.030
Why?
Adenine
1
2014
90
0.030
Why?
Jejunum
1
2014
76
0.030
Why?
B-Lymphocytes
1
2018
703
0.020
Why?
Golgi Apparatus
1
2014
108
0.020
Why?
Biomarkers
1
2020
1905
0.020
Why?
Microtubule-Associated Proteins
1
2014
184
0.020
Why?
RNA Interference
1
2014
379
0.020
Why?
Colforsin
1
2012
68
0.020
Why?
Biotinylation
1
2012
42
0.020
Why?
Diterpenes
1
2012
24
0.020
Why?
Adoptive Transfer
1
2013
173
0.020
Why?
Sequence Deletion
1
2013
206
0.020
Why?
Acrylamides
1
2012
34
0.020
Why?
Electric Conductivity
1
2012
142
0.020
Why?
Cholesterol, LDL
1
2014
246
0.020
Why?
Contrast Media
1
2016
986
0.020
Why?
Weight Loss
1
2013
234
0.020
Why?
Dopamine
1
2012
276
0.020
Why?
Retrospective Studies
1
2025
10132
0.020
Why?
Electrophysiology
1
2011
389
0.020
Why?
Luminescent Proteins
1
2011
141
0.020
Why?
MARVEL Domain Containing 2 Protein
1
2010
2
0.020
Why?
Microscopy, Immunoelectron
1
2010
28
0.020
Why?
Subcellular Fractions
1
2010
83
0.020
Why?
Tissue Culture Techniques
1
2010
80
0.020
Why?
Plasmids
1
2010
272
0.020
Why?
Sequence Homology, Amino Acid
1
2010
402
0.020
Why?
Dose-Response Relationship, Drug
1
2012
1908
0.020
Why?
Egtazic Acid
1
2008
32
0.020
Why?
Protein Kinase C-delta
1
2008
29
0.020
Why?
Carbazoles
1
2008
31
0.020
Why?
Protein Kinase C-alpha
1
2008
29
0.020
Why?
Mucous Membrane
1
2008
82
0.020
Why?
Major Histocompatibility Complex
1
2008
86
0.020
Why?
Microscopy, Electron, Transmission
1
2008
137
0.020
Why?
Microscopy, Confocal
1
2008
281
0.020
Why?
Adolescent
1
2020
9550
0.020
Why?
Lymphotoxin beta Receptor
1
2007
25
0.020
Why?
Cardiac Myosins
1
2007
19
0.020
Why?
Glucose
1
2009
686
0.020
Why?
Amino Acid Sequence
1
2010
1994
0.020
Why?
Base Sequence
1
2010
2207
0.020
Why?
Pyocyanine
1
2005
12
0.010
Why?
Molecular Sequence Data
1
2010
2889
0.010
Why?
CD4-Positive T-Lymphocytes
1
2008
481
0.010
Why?
Computer Systems
1
2005
63
0.010
Why?
Kidney
1
2009
1093
0.010
Why?
Virulence
1
2005
273
0.010
Why?
Phylogeny
1
2010
1268
0.010
Why?
RNA, Messenger
1
2010
2020
0.010
Why?
Escherichia coli Infections
1
2004
36
0.010
Why?
Severity of Illness Index
1
2008
1910
0.010
Why?
Aged, 80 and over
1
2013
7039
0.010
Why?
Nystatin
1
2002
2
0.010
Why?
Filipin
1
2002
2
0.010
Why?
Fas-Associated Death Domain Protein
1
2002
7
0.010
Why?
Cyclodextrins
1
2002
7
0.010
Why?
Ionophores
1
2002
14
0.010
Why?
Amino Acid Chloromethyl Ketones
1
2002
25
0.010
Why?
Caspase 8
1
2002
32
0.010
Why?
Caspase 9
1
2002
47
0.010
Why?
Caspase Inhibitors
1
2002
32
0.010
Why?
Membrane Microdomains
1
2002
52
0.010
Why?
Membrane Potentials
1
2002
404
0.010
Why?
Fluorescent Dyes
1
2002
255
0.010
Why?
Lymphocytes
1
2002
453
0.010
Why?
Mitochondria
1
2002
612
0.010
Why?
Anti-Bacterial Agents
1
2002
833
0.010
Why?
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