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Le Shen

Concepts (372)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tight Junctions
28
2022
153
3.690
Why?
Intestinal Mucosa
24
2020
824
2.410
Why?
Hemangioma, Cavernous, Central Nervous System
9
2022
259
1.790
Why?
Epithelium
8
2020
316
1.200
Why?
Epithelial Cells
13
2019
700
1.190
Why?
Occludin
16
2020
66
0.960
Why?
Endocytosis
8
2013
184
0.830
Why?
Membrane Proteins
16
2019
1264
0.820
Why?
Myosin-Light-Chain Kinase
11
2013
38
0.790
Why?
Claudins
8
2022
34
0.720
Why?
Zonula Occludens-1 Protein
12
2020
70
0.690
Why?
KRIT1 Protein
4
2022
62
0.690
Why?
Cell Membrane Permeability
5
2018
121
0.680
Why?
Myosin Type II
3
2018
50
0.620
Why?
rho-Associated Kinases
5
2018
161
0.610
Why?
Signal Transduction
13
2021
3502
0.580
Why?
Apoptosis
6
2021
1721
0.520
Why?
Colon
6
2025
540
0.510
Why?
Caco-2 Cells
13
2019
125
0.440
Why?
Animals
43
2025
28155
0.410
Why?
Actins
7
2018
467
0.400
Why?
Apoptosis Regulatory Proteins
5
2020
201
0.380
Why?
Tumor Necrosis Factor-alpha
8
2020
688
0.380
Why?
Phosphoproteins
8
2012
259
0.350
Why?
Mice
27
2025
12269
0.340
Why?
Paneth Cells
1
2020
10
0.320
Why?
Permeability
9
2015
143
0.320
Why?
Myosin Light Chains
5
2013
25
0.320
Why?
Stem Cell Niche
1
2020
23
0.320
Why?
Colitis
5
2019
261
0.320
Why?
Arginine
1
2020
141
0.310
Why?
Gastric Mucosa
1
2009
70
0.280
Why?
Adherens Junctions
1
2008
34
0.280
Why?
Intestine, Small
1
2020
310
0.280
Why?
Claudin-2
3
2017
10
0.270
Why?
Intestines
4
2020
432
0.270
Why?
Stem Cells
1
2020
387
0.270
Why?
Cadherins
1
2008
180
0.260
Why?
MicroRNAs
2
2022
580
0.260
Why?
Inflammatory Bowel Diseases
6
2025
646
0.260
Why?
Drug Resistance, Neoplasm
2
2021
636
0.260
Why?
Organoids
2
2022
76
0.250
Why?
Transcriptome
2
2025
762
0.250
Why?
Endothelium
2
2020
59
0.250
Why?
Phosphorylation
7
2018
1133
0.250
Why?
Caveolae
2
2007
6
0.250
Why?
Humans
41
2025
93515
0.240
Why?
Enterocolitis
1
2006
13
0.240
Why?
Mice, Inbred C57BL
12
2020
3435
0.240
Why?
Models, Biological
6
2020
1768
0.230
Why?
Protein-Arginine N-Methyltransferases
1
2025
22
0.220
Why?
Disease Models, Animal
9
2020
2495
0.220
Why?
Carcinoma, Adenoid Cystic
1
2025
43
0.210
Why?
Povidone-Iodine
1
2024
9
0.210
Why?
Microvilli
2
2018
44
0.210
Why?
Anti-Infective Agents, Local
1
2024
24
0.210
Why?
Colonic Pouches
1
2025
97
0.210
Why?
Proctocolectomy, Restorative
1
2025
115
0.210
Why?
Salivary Gland Neoplasms
1
2025
81
0.210
Why?
Recombinant Fusion Proteins
1
2005
555
0.200
Why?
Mice, Transgenic
10
2019
1587
0.200
Why?
Actin Cytoskeleton
5
2018
196
0.190
Why?
Dogs
5
2015
634
0.190
Why?
Circulating MicroRNA
1
2022
14
0.180
Why?
Cell Membrane
3
2018
664
0.180
Why?
Cell Line
8
2015
2464
0.180
Why?
Mebendazole
1
2021
8
0.170
Why?
Antinematodal Agents
1
2021
9
0.170
Why?
Sodium-Potassium-Chloride Symporters
2
2012
22
0.170
Why?
Brain
4
2020
2391
0.170
Why?
Claudin-1
4
2011
17
0.170
Why?
Eukaryotic Initiation Factor-4A
1
2020
3
0.170
Why?
Sterols
1
2020
19
0.160
Why?
5' Untranslated Regions
1
2020
52
0.160
Why?
Colitis, Ulcerative
2
2025
800
0.160
Why?
MAP Kinase Kinase Kinase 3
1
2020
13
0.160
Why?
Atrioventricular Node
1
2020
38
0.160
Why?
Hemangioma, Cavernous
1
2020
66
0.150
Why?
Plasma Cells
1
2020
84
0.150
Why?
Homeostasis
2
2020
460
0.150
Why?
rhoA GTP-Binding Protein
1
2020
87
0.150
Why?
Molecular Dynamics Simulation
2
2020
304
0.150
Why?
Cisplatin
1
2021
568
0.150
Why?
Autoantigens
1
2020
138
0.150
Why?
Caspase 3
1
2019
162
0.150
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2019
29
0.150
Why?
Autoantibodies
1
2020
277
0.140
Why?
Mutant Proteins
1
2019
98
0.140
Why?
Calcium
3
2019
1176
0.140
Why?
Up-Regulation
3
2017
730
0.140
Why?
Central Nervous System Neoplasms
1
2019
96
0.140
Why?
Ion Channels
1
2020
256
0.140
Why?
Cholesterol
2
2014
364
0.140
Why?
Mice, Knockout
7
2019
2121
0.140
Why?
Actomyosin
1
2018
47
0.140
Why?
T-Box Domain Proteins
1
2019
127
0.130
Why?
Gastrointestinal Tract
1
2019
195
0.130
Why?
ATP-Binding Cassette Transporters
1
2018
140
0.130
Why?
Heart Rate
1
2020
505
0.130
Why?
Enterobacteriaceae Infections
1
2017
24
0.130
Why?
Idiopathic Pulmonary Fibrosis
1
2020
210
0.130
Why?
Interleukins
1
2017
133
0.120
Why?
Cytoskeleton
2
2008
198
0.120
Why?
Microtubules
2
2014
134
0.120
Why?
Diarrhea
1
2017
179
0.120
Why?
Gastrointestinal Microbiome
2
2020
590
0.120
Why?
Proto-Oncogene Proteins
1
2019
666
0.120
Why?
Mycobacterium tuberculosis
1
2018
208
0.120
Why?
Cell Line, Tumor
5
2025
2755
0.120
Why?
X-Ray Microtomography
1
2016
101
0.120
Why?
Cell Proliferation
3
2025
1741
0.120
Why?
Enterovirus B, Human
1
2015
9
0.110
Why?
Enterovirus Infections
1
2015
25
0.110
Why?
CD55 Antigens
1
2015
21
0.110
Why?
Disease Progression
1
2019
1531
0.110
Why?
Protein Transport
4
2014
438
0.110
Why?
Biological Transport
1
2015
404
0.110
Why?
Ovarian Neoplasms
1
2021
797
0.110
Why?
Sterol Regulatory Element Binding Protein 2
1
2014
5
0.100
Why?
Disease Susceptibility
1
2015
220
0.100
Why?
Atrial Fibrillation
1
2019
417
0.100
Why?
Protein Binding
6
2018
1534
0.100
Why?
Liver Diseases
1
2015
243
0.100
Why?
Dextran Sulfate
3
2019
70
0.100
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2013
20
0.100
Why?
Microscopy, Fluorescence
4
2010
436
0.100
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2013
40
0.100
Why?
Ethanol
1
2015
273
0.100
Why?
Caveolin 1
2
2010
24
0.100
Why?
Capsaicin
1
2012
43
0.100
Why?
TRPV Cation Channels
1
2012
16
0.090
Why?
Casein Kinase II
1
2012
11
0.090
Why?
Lymphatic Vessels
1
2013
69
0.090
Why?
Chlorides
1
2012
101
0.090
Why?
Endothelial Cells
3
2020
477
0.090
Why?
Real-Time Polymerase Chain Reaction
3
2022
296
0.090
Why?
Bridged Bicyclo Compounds, Heterocyclic
3
2012
98
0.090
Why?
Xenograft Model Antitumor Assays
2
2025
526
0.090
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2012
111
0.090
Why?
Lung
2
2020
1366
0.080
Why?
Reverse Transcriptase Polymerase Chain Reaction
3
2022
887
0.080
Why?
Wound Healing
2
2021
373
0.080
Why?
Protein Kinase C
2
2008
261
0.080
Why?
Protein Interaction Domains and Motifs
1
2011
86
0.080
Why?
Antineoplastic Agents
1
2021
2303
0.080
Why?
Immunity, Innate
2
2017
463
0.080
Why?
Interferon-gamma
3
2008
460
0.080
Why?
T-Lymphocyte Subsets
1
2012
287
0.080
Why?
Dynamin II
2
2011
15
0.080
Why?
Myosin Heavy Chains
2
2020
86
0.080
Why?
Interleukin-13
1
2010
41
0.080
Why?
Clathrin
1
2009
31
0.080
Why?
Tetradecanoylphorbol Acetate
1
2009
122
0.080
Why?
Wnt Signaling Pathway
1
2020
103
0.080
Why?
Binding Sites
3
2018
1133
0.070
Why?
cdc42 GTP-Binding Protein
1
2008
12
0.070
Why?
Microscopy, Electron
2
2022
439
0.070
Why?
Immunity, Mucosal
1
2009
71
0.070
Why?
Fluorescence Recovery After Photobleaching
1
2008
12
0.070
Why?
Immunohistochemistry
4
2015
1799
0.070
Why?
Sodium-Hydrogen Exchangers
1
2008
78
0.070
Why?
Diffusion
1
2008
90
0.070
Why?
Thiazolidines
2
2005
15
0.070
Why?
Case-Control Studies
2
2025
1931
0.070
Why?
Intracellular Signaling Peptides and Proteins
3
2018
392
0.070
Why?
DNA Primers
2
2022
531
0.070
Why?
Organ Specificity
1
2009
279
0.070
Why?
Multiprotein Complexes
1
2008
106
0.070
Why?
Cell Polarity
1
2008
118
0.070
Why?
Acute Disease
2
2020
841
0.060
Why?
Thiazoles
2
2005
124
0.060
Why?
Time Factors
4
2024
5410
0.060
Why?
Tumor Necrosis Factor Ligand Superfamily Member 14
1
2007
14
0.060
Why?
Bacterial Infections
1
2009
179
0.060
Why?
Serotonin
1
2008
209
0.060
Why?
Female
8
2025
48702
0.060
Why?
Myocytes, Cardiac
2
2020
313
0.060
Why?
Claudin-4
2
2020
8
0.060
Why?
Cells, Cultured
3
2019
2850
0.060
Why?
Enzyme Induction
1
2006
83
0.060
Why?
Chronic Disease
2
2020
960
0.060
Why?
RNA, Small Interfering
3
2014
555
0.060
Why?
Crohn Disease
2
2025
808
0.060
Why?
Cytokines
4
2017
863
0.060
Why?
Intestinal Absorption
1
2006
125
0.060
Why?
T-Lymphocytes
2
2018
1275
0.060
Why?
Clathrin-Coated Vesicles
1
2005
10
0.060
Why?
Porins
1
2005
24
0.060
Why?
Adhesins, Bacterial
1
2005
36
0.060
Why?
Lectins
1
2005
83
0.060
Why?
Male
7
2025
44557
0.050
Why?
Genes, Reporter
1
2005
275
0.050
Why?
Ion Transport
2
2018
84
0.050
Why?
Drug Storage
1
2024
4
0.050
Why?
Ophthalmic Solutions
1
2024
14
0.050
Why?
Computational Biology
1
2008
578
0.050
Why?
Eye Infections, Bacterial
1
2024
12
0.050
Why?
Triglycerides
2
2015
231
0.050
Why?
Drosophila
1
2008
539
0.050
Why?
Microbial Sensitivity Tests
1
2024
146
0.050
Why?
Colectomy
1
2025
192
0.050
Why?
Middle Aged
5
2025
27573
0.050
Why?
Drosophila Proteins
1
2008
521
0.050
Why?
Computer Simulation
1
2008
1118
0.050
Why?
Pseudomonas aeruginosa
1
2005
199
0.050
Why?
Cell Movement
2
2021
809
0.050
Why?
Reproducibility of Results
2
2022
2715
0.050
Why?
Single-Cell Analysis
1
2025
198
0.050
Why?
Tissue Distribution
3
2010
291
0.050
Why?
Freeze Fracturing
1
2022
11
0.050
Why?
Phenotype
2
2020
2544
0.050
Why?
Receptor Aggregation
1
2002
3
0.050
Why?
beta-Cyclodextrins
1
2002
10
0.050
Why?
Gene Knockdown Techniques
2
2013
254
0.040
Why?
Ligands
2
2019
476
0.040
Why?
Blotting, Western
2
2014
784
0.040
Why?
fas Receptor
1
2002
73
0.040
Why?
Drug Discovery
1
2022
113
0.040
Why?
Tumor Stem Cell Assay
1
2021
41
0.040
Why?
Solute Carrier Family 12, Member 2
2
2012
16
0.040
Why?
Drug Repositioning
1
2021
26
0.040
Why?
Adult
4
2025
27918
0.040
Why?
Green Fluorescent Proteins
2
2012
309
0.040
Why?
Young Adult
2
2025
6930
0.040
Why?
Cyclic N-Oxides
1
2020
32
0.040
Why?
Protein Structure, Tertiary
2
2013
729
0.040
Why?
Bayes Theorem
1
2022
402
0.040
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2020
36
0.040
Why?
Cholecalciferol
1
2020
35
0.040
Why?
Vimentin
1
2020
47
0.040
Why?
Spin Labels
1
2020
105
0.040
Why?
Bacteria
1
2024
509
0.040
Why?
Carrier Proteins
2
2019
663
0.040
Why?
Tight Junction Proteins
1
2020
14
0.040
Why?
Adaptor Proteins, Signal Transducing
1
2002
304
0.040
Why?
Tubulin
1
2020
61
0.040
Why?
Liver
2
2015
1210
0.040
Why?
Alveolar Epithelial Cells
1
2020
18
0.040
Why?
Ribosomes
1
2020
102
0.040
Why?
CRISPR-Cas Systems
1
2020
98
0.040
Why?
Connexin 43
1
2020
94
0.040
Why?
Trinitrobenzenesulfonic Acid
1
2019
16
0.040
Why?
Astrocytes
1
2020
141
0.040
Why?
Metagenomics
1
2020
100
0.040
Why?
Mice, Nude
1
2021
824
0.040
Why?
Potassium Channels, Voltage-Gated
1
2020
111
0.040
Why?
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
1
2020
175
0.040
Why?
Gene Expression Profiling
1
2025
1518
0.040
Why?
Respiratory Mucosa
1
2020
90
0.040
Why?
Gene Expression Regulation, Neoplastic
1
2025
1338
0.040
Why?
DNA, Bacterial
1
2020
232
0.040
Why?
RNA, Ribosomal, 16S
1
2020
259
0.040
Why?
Cations, Divalent
1
2019
36
0.040
Why?
Cost-Benefit Analysis
1
2022
492
0.040
Why?
Toll-Like Receptor 4
1
2019
91
0.040
Why?
Gene Deletion
1
2020
352
0.040
Why?
Lipopolysaccharides
1
2020
301
0.040
Why?
High-Throughput Nucleotide Sequencing
1
2022
537
0.040
Why?
Zonula Occludens-2 Protein
1
2018
11
0.040
Why?
Biological Transport, Active
1
2018
99
0.040
Why?
Connexins
1
2020
206
0.040
Why?
Phosphothreonine
1
2018
4
0.040
Why?
Hemorrhage
1
2020
288
0.030
Why?
Feces
1
2020
360
0.030
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2018
65
0.030
Why?
Dynamins
1
2018
48
0.030
Why?
Dexamethasone
1
2019
312
0.030
Why?
Enzyme Activation
2
2010
674
0.030
Why?
HEK293 Cells
1
2020
696
0.030
Why?
Mutation
2
2020
4272
0.030
Why?
Iron
1
2018
174
0.030
Why?
Citrobacter rodentium
1
2017
14
0.030
Why?
Cytoplasm
1
2018
278
0.030
Why?
Pilot Projects
1
2020
917
0.030
Why?
Protein Structure, Secondary
1
2018
337
0.030
Why?
Protein Multimerization
1
2018
191
0.030
Why?
Microfilament Proteins
1
2018
209
0.030
Why?
Gene Regulatory Networks
1
2019
317
0.030
Why?
Caspases
2
2011
151
0.030
Why?
Crystallography, X-Ray
1
2018
520
0.030
Why?
Cerebellum
1
2018
248
0.030
Why?
Histological Techniques
1
2016
33
0.030
Why?
Iodine
1
2016
43
0.030
Why?
Aged
3
2020
20434
0.030
Why?
Inulin
1
2015
17
0.030
Why?
Sodium
1
2017
329
0.030
Why?
Recombinant Proteins
2
2010
988
0.030
Why?
Water
1
2017
307
0.030
Why?
Organ Size
1
2016
362
0.030
Why?
Observer Variation
1
2016
570
0.030
Why?
Patch-Clamp Techniques
1
2015
378
0.030
Why?
Risk Factors
1
2025
5899
0.030
Why?
Dynactin Complex
1
2014
2
0.030
Why?
Benzyl Compounds
1
2014
7
0.030
Why?
Nocodazole
1
2014
18
0.030
Why?
Dyneins
1
2014
14
0.030
Why?
Immunoblotting
1
2015
273
0.030
Why?
Madin Darby Canine Kidney Cells
1
2014
23
0.030
Why?
Tubulin Modulators
1
2014
23
0.030
Why?
Fluorescent Antibody Technique
1
2015
308
0.030
Why?
Lymphocyte Activation
2
2009
797
0.030
Why?
Brain Neoplasms
1
2020
813
0.030
Why?
Cholesterol, VLDL
1
2014
14
0.030
Why?
Adenine
1
2014
90
0.030
Why?
Models, Molecular
1
2018
1353
0.030
Why?
Jejunum
1
2014
76
0.030
Why?
B-Lymphocytes
1
2018
701
0.030
Why?
Golgi Apparatus
1
2014
115
0.020
Why?
Biomarkers
1
2020
1910
0.020
Why?
Microtubule-Associated Proteins
1
2014
185
0.020
Why?
RNA Interference
1
2014
379
0.020
Why?
Colforsin
1
2012
69
0.020
Why?
Biotinylation
1
2012
42
0.020
Why?
Diterpenes
1
2012
24
0.020
Why?
Adoptive Transfer
1
2013
172
0.020
Why?
Sequence Deletion
1
2013
209
0.020
Why?
Acrylamides
1
2012
34
0.020
Why?
Electric Conductivity
1
2012
142
0.020
Why?
Cholesterol, LDL
1
2014
246
0.020
Why?
Contrast Media
1
2016
988
0.020
Why?
Weight Loss
1
2013
234
0.020
Why?
Dopamine
1
2012
276
0.020
Why?
Retrospective Studies
1
2025
10164
0.020
Why?
Electrophysiology
1
2011
390
0.020
Why?
Luminescent Proteins
1
2011
141
0.020
Why?
MARVEL Domain Containing 2 Protein
1
2010
2
0.020
Why?
Microscopy, Immunoelectron
1
2010
28
0.020
Why?
Subcellular Fractions
1
2010
88
0.020
Why?
Tissue Culture Techniques
1
2010
81
0.020
Why?
Plasmids
1
2010
273
0.020
Why?
Sequence Homology, Amino Acid
1
2010
404
0.020
Why?
Dose-Response Relationship, Drug
1
2012
1914
0.020
Why?
Egtazic Acid
1
2008
32
0.020
Why?
Protein Kinase C-delta
1
2008
29
0.020
Why?
Carbazoles
1
2008
31
0.020
Why?
Protein Kinase C-alpha
1
2008
29
0.020
Why?
Mucous Membrane
1
2008
82
0.020
Why?
Major Histocompatibility Complex
1
2008
86
0.020
Why?
Microscopy, Electron, Transmission
1
2008
137
0.020
Why?
Microscopy, Confocal
1
2008
282
0.020
Why?
Adolescent
1
2020
9606
0.020
Why?
Lymphotoxin beta Receptor
1
2007
25
0.020
Why?
Cardiac Myosins
1
2007
19
0.020
Why?
Glucose
1
2009
692
0.020
Why?
Amino Acid Sequence
1
2010
2012
0.020
Why?
Base Sequence
1
2010
2220
0.020
Why?
Pyocyanine
1
2005
12
0.010
Why?
Molecular Sequence Data
1
2010
2910
0.010
Why?
CD4-Positive T-Lymphocytes
1
2008
481
0.010
Why?
Computer Systems
1
2005
64
0.010
Why?
Kidney
1
2009
1111
0.010
Why?
Virulence
1
2005
273
0.010
Why?
Phylogeny
1
2010
1266
0.010
Why?
RNA, Messenger
1
2010
2026
0.010
Why?
Escherichia coli Infections
1
2004
36
0.010
Why?
Severity of Illness Index
1
2008
1917
0.010
Why?
Aged, 80 and over
1
2013
7061
0.010
Why?
Nystatin
1
2002
2
0.010
Why?
Filipin
1
2002
2
0.010
Why?
Fas-Associated Death Domain Protein
1
2002
7
0.010
Why?
Cyclodextrins
1
2002
7
0.010
Why?
Ionophores
1
2002
14
0.010
Why?
Amino Acid Chloromethyl Ketones
1
2002
25
0.010
Why?
Caspase 8
1
2002
32
0.010
Why?
Caspase 9
1
2002
47
0.010
Why?
Caspase Inhibitors
1
2002
32
0.010
Why?
Membrane Microdomains
1
2002
53
0.010
Why?
Membrane Potentials
1
2002
405
0.010
Why?
Fluorescent Dyes
1
2002
257
0.010
Why?
Lymphocytes
1
2002
454
0.010
Why?
Mitochondria
1
2002
612
0.010
Why?
Anti-Bacterial Agents
1
2002
836
0.010
Why?
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