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Le Shen

Concepts (350)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tight Junctions
28
2022
151
4.020
Why?
Intestinal Mucosa
24
2020
807
2.590
Why?
Hemangioma, Cavernous, Central Nervous System
9
2022
229
1.990
Why?
Epithelium
8
2020
323
1.290
Why?
Epithelial Cells
13
2019
693
1.280
Why?
Occludin
16
2020
66
1.040
Why?
Endocytosis
8
2013
184
0.910
Why?
Membrane Proteins
16
2019
1232
0.900
Why?
Myosin-Light-Chain Kinase
11
2013
41
0.860
Why?
Claudins
8
2022
33
0.780
Why?
Zonula Occludens-1 Protein
12
2020
70
0.760
Why?
KRIT1 Protein
4
2022
62
0.750
Why?
Cell Membrane Permeability
5
2018
121
0.740
Why?
Myosin Type II
3
2018
50
0.670
Why?
rho-Associated Kinases
5
2018
160
0.660
Why?
Signal Transduction
13
2021
3431
0.630
Why?
Apoptosis
6
2021
1725
0.560
Why?
Caco-2 Cells
13
2019
123
0.490
Why?
Animals
43
2025
27715
0.440
Why?
Actins
7
2018
469
0.430
Why?
Apoptosis Regulatory Proteins
5
2020
198
0.420
Why?
Tumor Necrosis Factor-alpha
8
2020
705
0.410
Why?
Phosphoproteins
8
2012
262
0.380
Why?
Mice
27
2025
11949
0.370
Why?
Colon
5
2022
522
0.360
Why?
Paneth Cells
1
2020
10
0.350
Why?
Permeability
9
2015
138
0.350
Why?
Myosin Light Chains
5
2013
29
0.350
Why?
Stem Cell Niche
1
2020
23
0.350
Why?
Colitis
5
2019
249
0.340
Why?
Arginine
1
2020
141
0.340
Why?
Adherens Junctions
1
2008
34
0.310
Why?
Gastric Mucosa
1
2009
68
0.310
Why?
Intestine, Small
1
2020
299
0.300
Why?
Claudin-2
3
2017
10
0.300
Why?
Cadherins
1
2008
164
0.290
Why?
Intestines
4
2020
416
0.290
Why?
Stem Cells
1
2020
380
0.290
Why?
Organoids
2
2022
69
0.280
Why?
MicroRNAs
2
2022
561
0.280
Why?
Endothelium
2
2020
58
0.270
Why?
Caveolae
2
2007
6
0.270
Why?
Phosphorylation
7
2018
1132
0.270
Why?
Enterocolitis
1
2006
13
0.260
Why?
Mice, Inbred C57BL
12
2020
3278
0.260
Why?
Models, Biological
6
2020
1770
0.250
Why?
Humans
39
2025
90640
0.250
Why?
Protein-Arginine N-Methyltransferases
1
2025
21
0.240
Why?
Disease Models, Animal
9
2020
2409
0.230
Why?
Povidone-Iodine
1
2024
9
0.230
Why?
Microvilli
2
2018
43
0.230
Why?
Carcinoma, Adenoid Cystic
1
2025
43
0.230
Why?
Anti-Infective Agents, Local
1
2024
24
0.230
Why?
Salivary Gland Neoplasms
1
2025
80
0.220
Why?
Recombinant Fusion Proteins
1
2005
565
0.220
Why?
Mice, Transgenic
10
2019
1583
0.210
Why?
Actin Cytoskeleton
5
2018
199
0.200
Why?
Dogs
5
2015
704
0.200
Why?
Circulating MicroRNA
1
2022
13
0.200
Why?
Cell Membrane
3
2018
683
0.190
Why?
Cell Line
8
2015
2505
0.190
Why?
Mebendazole
1
2021
8
0.190
Why?
Antinematodal Agents
1
2021
9
0.190
Why?
Sodium-Potassium-Chloride Symporters
2
2012
22
0.190
Why?
Brain
4
2020
2328
0.180
Why?
Claudin-1
4
2011
17
0.180
Why?
MAP Kinase Kinase Kinase 3
1
2020
13
0.170
Why?
Atrioventricular Node
1
2020
35
0.170
Why?
Homeostasis
2
2020
425
0.170
Why?
Hemangioma, Cavernous
1
2020
69
0.170
Why?
Plasma Cells
1
2020
85
0.170
Why?
Molecular Dynamics Simulation
2
2020
266
0.160
Why?
rhoA GTP-Binding Protein
1
2020
85
0.160
Why?
Autoantigens
1
2020
132
0.160
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2019
25
0.160
Why?
Caspase 3
1
2019
162
0.160
Why?
Cisplatin
1
2021
599
0.160
Why?
Autoantibodies
1
2020
275
0.160
Why?
Mutant Proteins
1
2019
97
0.160
Why?
Central Nervous System Neoplasms
1
2019
86
0.150
Why?
Calcium
3
2019
1183
0.150
Why?
Up-Regulation
3
2017
728
0.150
Why?
Ion Channels
1
2020
246
0.150
Why?
Cholesterol
2
2014
362
0.150
Why?
Actomyosin
1
2018
47
0.150
Why?
Mice, Knockout
7
2019
2042
0.150
Why?
T-Box Domain Proteins
1
2019
126
0.150
Why?
Gastrointestinal Tract
1
2019
192
0.150
Why?
Heart Rate
1
2020
496
0.140
Why?
Drug Resistance, Neoplasm
1
2021
610
0.140
Why?
Enterobacteriaceae Infections
1
2017
24
0.140
Why?
Idiopathic Pulmonary Fibrosis
1
2020
205
0.140
Why?
Interleukins
1
2017
132
0.140
Why?
Gastrointestinal Microbiome
2
2020
526
0.130
Why?
Microtubules
2
2014
129
0.130
Why?
Cytoskeleton
2
2008
201
0.130
Why?
Diarrhea
1
2017
178
0.130
Why?
Proto-Oncogene Proteins
1
2019
665
0.130
Why?
X-Ray Microtomography
1
2016
93
0.130
Why?
Inflammatory Bowel Diseases
5
2013
599
0.130
Why?
Cell Proliferation
3
2025
1695
0.120
Why?
Enterovirus B, Human
1
2015
10
0.120
Why?
CD55 Antigens
1
2015
21
0.120
Why?
Enterovirus Infections
1
2015
41
0.120
Why?
Protein Transport
4
2014
426
0.120
Why?
Disease Progression
1
2019
1486
0.120
Why?
Biological Transport
1
2015
403
0.120
Why?
Ovarian Neoplasms
1
2021
776
0.120
Why?
Atrial Fibrillation
1
2019
361
0.110
Why?
Sterol Regulatory Element Binding Protein 2
1
2014
4
0.110
Why?
Transcriptome
1
2019
674
0.110
Why?
Disease Susceptibility
1
2015
200
0.110
Why?
Liver Diseases
1
2015
243
0.110
Why?
Dextran Sulfate
3
2019
69
0.110
Why?
Receptors, Tumor Necrosis Factor, Type II
1
2013
20
0.110
Why?
Microscopy, Fluorescence
4
2010
441
0.110
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2013
44
0.110
Why?
Ethanol
1
2015
257
0.110
Why?
Caveolin 1
2
2010
23
0.100
Why?
Capsaicin
1
2012
45
0.100
Why?
TRPV Cation Channels
1
2012
16
0.100
Why?
Casein Kinase II
1
2012
11
0.100
Why?
Chlorides
1
2012
104
0.100
Why?
Lymphatic Vessels
1
2013
69
0.100
Why?
Real-Time Polymerase Chain Reaction
3
2022
285
0.100
Why?
Cell Line, Tumor
4
2025
2609
0.100
Why?
Endothelial Cells
3
2020
467
0.100
Why?
Bridged Bicyclo Compounds, Heterocyclic
3
2012
92
0.100
Why?
Xenograft Model Antitumor Assays
2
2025
491
0.090
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2012
105
0.090
Why?
Lung
2
2020
1305
0.090
Why?
Wound Healing
2
2021
365
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
3
2022
888
0.090
Why?
Protein Kinase C
2
2008
267
0.090
Why?
Protein Interaction Domains and Motifs
1
2011
87
0.090
Why?
Immunity, Innate
2
2017
437
0.090
Why?
T-Lymphocyte Subsets
1
2012
277
0.090
Why?
Interferon-gamma
3
2008
449
0.090
Why?
Dynamin II
2
2011
15
0.090
Why?
Antineoplastic Agents
1
2021
2337
0.090
Why?
Interleukin-13
1
2010
38
0.080
Why?
Myosin Heavy Chains
2
2020
92
0.080
Why?
Clathrin
1
2009
32
0.080
Why?
Tetradecanoylphorbol Acetate
1
2009
137
0.080
Why?
Protein Binding
5
2013
1500
0.080
Why?
Wnt Signaling Pathway
1
2020
103
0.080
Why?
cdc42 GTP-Binding Protein
1
2008
12
0.080
Why?
Microscopy, Electron
2
2022
511
0.080
Why?
Immunity, Mucosal
1
2009
70
0.080
Why?
Fluorescence Recovery After Photobleaching
1
2008
13
0.080
Why?
Immunohistochemistry
4
2015
1806
0.080
Why?
Sodium-Hydrogen Exchangers
1
2008
78
0.080
Why?
Diffusion
1
2008
94
0.080
Why?
Thiazolidines
2
2005
17
0.080
Why?
Organ Specificity
1
2009
279
0.070
Why?
Intracellular Signaling Peptides and Proteins
3
2018
388
0.070
Why?
DNA Primers
2
2022
546
0.070
Why?
Multiprotein Complexes
1
2008
96
0.070
Why?
Cell Polarity
1
2008
116
0.070
Why?
Tumor Necrosis Factor Ligand Superfamily Member 14
1
2007
14
0.070
Why?
Acute Disease
2
2020
854
0.070
Why?
Thiazoles
2
2005
127
0.070
Why?
Time Factors
4
2024
5366
0.070
Why?
Bacterial Infections
1
2009
185
0.070
Why?
Serotonin
1
2008
221
0.070
Why?
Myocytes, Cardiac
2
2020
316
0.070
Why?
Claudin-4
2
2020
8
0.070
Why?
Enzyme Induction
1
2006
88
0.070
Why?
Cells, Cultured
3
2019
2895
0.060
Why?
Chronic Disease
2
2020
959
0.060
Why?
Cytokines
4
2017
814
0.060
Why?
RNA, Small Interfering
3
2014
558
0.060
Why?
Intestinal Absorption
1
2006
125
0.060
Why?
T-Lymphocytes
2
2018
1229
0.060
Why?
Clathrin-Coated Vesicles
1
2005
10
0.060
Why?
Porins
1
2005
21
0.060
Why?
Adhesins, Bacterial
1
2005
36
0.060
Why?
Lectins
1
2005
84
0.060
Why?
Ion Transport
2
2018
85
0.060
Why?
Genes, Reporter
1
2005
274
0.060
Why?
Computational Biology
1
2008
552
0.060
Why?
Drug Storage
1
2024
4
0.060
Why?
Ophthalmic Solutions
1
2024
17
0.060
Why?
Drosophila
1
2008
522
0.060
Why?
Eye Infections, Bacterial
1
2024
16
0.060
Why?
Triglycerides
2
2015
235
0.060
Why?
Female
7
2025
46894
0.060
Why?
Microbial Sensitivity Tests
1
2024
151
0.060
Why?
Drosophila Proteins
1
2008
510
0.060
Why?
Pseudomonas aeruginosa
1
2005
203
0.050
Why?
Cell Movement
2
2021
793
0.050
Why?
Computer Simulation
1
2008
1103
0.050
Why?
Freeze Fracturing
1
2022
12
0.050
Why?
Tissue Distribution
3
2010
293
0.050
Why?
Reproducibility of Results
2
2022
2782
0.050
Why?
Phenotype
2
2020
2473
0.050
Why?
Receptor Aggregation
1
2002
3
0.050
Why?
beta-Cyclodextrins
1
2002
9
0.050
Why?
Ligands
2
2019
453
0.050
Why?
Binding Sites
2
2018
1127
0.050
Why?
Gene Knockdown Techniques
2
2013
252
0.050
Why?
fas Receptor
1
2002
77
0.050
Why?
Tumor Stem Cell Assay
1
2021
39
0.050
Why?
Blotting, Western
2
2014
795
0.050
Why?
Drug Discovery
1
2022
110
0.050
Why?
Solute Carrier Family 12, Member 2
2
2012
16
0.050
Why?
Male
6
2020
42967
0.050
Why?
Drug Repositioning
1
2021
25
0.050
Why?
Cyclic N-Oxides
1
2020
33
0.040
Why?
Green Fluorescent Proteins
2
2012
309
0.040
Why?
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
1
2020
36
0.040
Why?
Cholecalciferol
1
2020
35
0.040
Why?
Protein Structure, Tertiary
2
2013
742
0.040
Why?
Bayes Theorem
1
2022
385
0.040
Why?
Vimentin
1
2020
46
0.040
Why?
Bacteria
1
2024
488
0.040
Why?
Spin Labels
1
2020
107
0.040
Why?
Tight Junction Proteins
1
2020
14
0.040
Why?
Tubulin
1
2020
60
0.040
Why?
Alveolar Epithelial Cells
1
2020
18
0.040
Why?
Liver
2
2015
1218
0.040
Why?
Adaptor Proteins, Signal Transducing
1
2002
315
0.040
Why?
Carrier Proteins
2
2019
679
0.040
Why?
Trinitrobenzenesulfonic Acid
1
2019
16
0.040
Why?
Connexin 43
1
2020
94
0.040
Why?
Astrocytes
1
2020
145
0.040
Why?
Metagenomics
1
2020
93
0.040
Why?
Respiratory Mucosa
1
2020
88
0.040
Why?
Mice, Nude
1
2021
819
0.040
Why?
DNA, Bacterial
1
2020
245
0.040
Why?
Cations, Divalent
1
2019
39
0.040
Why?
Middle Aged
4
2020
26347
0.040
Why?
RNA, Ribosomal, 16S
1
2020
252
0.040
Why?
Potassium Channels, Voltage-Gated
1
2020
125
0.040
Why?
Toll-Like Receptor 4
1
2019
91
0.040
Why?
Cost-Benefit Analysis
1
2022
474
0.040
Why?
Gene Deletion
1
2020
345
0.040
Why?
High-Throughput Nucleotide Sequencing
1
2022
493
0.040
Why?
Lipopolysaccharides
1
2020
295
0.040
Why?
Zonula Occludens-2 Protein
1
2018
11
0.040
Why?
Biological Transport, Active
1
2018
102
0.040
Why?
Connexins
1
2020
202
0.040
Why?
Feces
1
2020
335
0.040
Why?
Hemorrhage
1
2020
290
0.040
Why?
Dynamins
1
2018
50
0.040
Why?
Dexamethasone
1
2019
345
0.040
Why?
HEK293 Cells
1
2020
660
0.040
Why?
Enzyme Activation
2
2010
697
0.040
Why?
Citrobacter rodentium
1
2017
14
0.040
Why?
Iron
1
2018
173
0.040
Why?
Pilot Projects
1
2020
879
0.040
Why?
Protein Multimerization
1
2018
182
0.040
Why?
Gene Regulatory Networks
1
2019
309
0.030
Why?
Microfilament Proteins
1
2018
211
0.030
Why?
Caspases
2
2011
155
0.030
Why?
Histological Techniques
1
2016
36
0.030
Why?
Cerebellum
1
2018
250
0.030
Why?
Aged
3
2020
19424
0.030
Why?
Iodine
1
2016
44
0.030
Why?
Inulin
1
2015
17
0.030
Why?
Sodium
1
2017
334
0.030
Why?
Recombinant Proteins
2
2010
1015
0.030
Why?
Water
1
2017
287
0.030
Why?
Organ Size
1
2016
375
0.030
Why?
Case-Control Studies
1
2019
1873
0.030
Why?
Dynactin Complex
1
2014
2
0.030
Why?
Patch-Clamp Techniques
1
2015
397
0.030
Why?
Benzyl Compounds
1
2014
7
0.030
Why?
Nocodazole
1
2014
18
0.030
Why?
Observer Variation
1
2016
615
0.030
Why?
Dyneins
1
2014
14
0.030
Why?
Madin Darby Canine Kidney Cells
1
2014
19
0.030
Why?
Immunoblotting
1
2015
272
0.030
Why?
Lymphocyte Activation
2
2009
756
0.030
Why?
Tubulin Modulators
1
2014
23
0.030
Why?
Adult
3
2020
26953
0.030
Why?
Fluorescent Antibody Technique
1
2015
324
0.030
Why?
Brain Neoplasms
1
2020
781
0.030
Why?
Cholesterol, VLDL
1
2014
14
0.030
Why?
Adenine
1
2014
88
0.030
Why?
Jejunum
1
2014
80
0.030
Why?
Golgi Apparatus
1
2014
117
0.030
Why?
B-Lymphocytes
1
2018
741
0.030
Why?
Biomarkers
1
2020
1800
0.030
Why?
Microtubule-Associated Proteins
1
2014
184
0.030
Why?
RNA Interference
1
2014
377
0.030
Why?
Colforsin
1
2012
74
0.030
Why?
Sequence Deletion
1
2013
205
0.030
Why?
Diterpenes
1
2012
22
0.030
Why?
Acrylamides
1
2012
34
0.030
Why?
Biotinylation
1
2012
43
0.030
Why?
Adoptive Transfer
1
2013
170
0.030
Why?
Electric Conductivity
1
2012
144
0.030
Why?
Crohn Disease
1
2019
765
0.030
Why?
Cholesterol, LDL
1
2014
228
0.030
Why?
Colitis, Ulcerative
1
2019
763
0.030
Why?
Weight Loss
1
2013
235
0.020
Why?
Contrast Media
1
2016
1085
0.020
Why?
Dopamine
1
2012
277
0.020
Why?
Luminescent Proteins
1
2011
144
0.020
Why?
Electrophysiology
1
2011
403
0.020
Why?
MARVEL Domain Containing 2 Protein
1
2010
2
0.020
Why?
Microscopy, Immunoelectron
1
2010
29
0.020
Why?
Subcellular Fractions
1
2010
94
0.020
Why?
Tissue Culture Techniques
1
2010
83
0.020
Why?
Plasmids
1
2010
292
0.020
Why?
Sequence Homology, Amino Acid
1
2010
419
0.020
Why?
Egtazic Acid
1
2008
33
0.020
Why?
Protein Kinase C-delta
1
2008
28
0.020
Why?
Protein Kinase C-alpha
1
2008
27
0.020
Why?
Dose-Response Relationship, Drug
1
2012
1935
0.020
Why?
Mucous Membrane
1
2008
83
0.020
Why?
Carbazoles
1
2008
33
0.020
Why?
Major Histocompatibility Complex
1
2008
84
0.020
Why?
Microscopy, Electron, Transmission
1
2008
136
0.020
Why?
Young Adult
1
2020
6426
0.020
Why?
Microscopy, Confocal
1
2008
283
0.020
Why?
Adolescent
1
2020
9354
0.020
Why?
Lymphotoxin beta Receptor
1
2007
29
0.020
Why?
Cardiac Myosins
1
2007
19
0.020
Why?
Glucose
1
2009
635
0.020
Why?
Mutation
1
2018
4183
0.020
Why?
Amino Acid Sequence
1
2010
2077
0.020
Why?
Base Sequence
1
2010
2329
0.020
Why?
Pyocyanine
1
2005
12
0.020
Why?
CD4-Positive T-Lymphocytes
1
2008
453
0.020
Why?
Molecular Sequence Data
1
2010
3030
0.020
Why?
Computer Systems
1
2005
79
0.020
Why?
Virulence
1
2005
282
0.010
Why?
Kidney
1
2009
1150
0.010
Why?
Phylogeny
1
2010
1219
0.010
Why?
Escherichia coli Infections
1
2004
34
0.010
Why?
RNA, Messenger
1
2010
2034
0.010
Why?
Severity of Illness Index
1
2008
1882
0.010
Why?
Nystatin
1
2002
2
0.010
Why?
Filipin
1
2002
2
0.010
Why?
Fas-Associated Death Domain Protein
1
2002
8
0.010
Why?
Aged, 80 and over
1
2013
6816
0.010
Why?
Cyclodextrins
1
2002
7
0.010
Why?
Ionophores
1
2002
14
0.010
Why?
Amino Acid Chloromethyl Ketones
1
2002
25
0.010
Why?
Caspase 8
1
2002
34
0.010
Why?
Caspase 9
1
2002
49
0.010
Why?
Caspase Inhibitors
1
2002
33
0.010
Why?
Membrane Microdomains
1
2002
54
0.010
Why?
Membrane Potentials
1
2002
437
0.010
Why?
Fluorescent Dyes
1
2002
254
0.010
Why?
Lymphocytes
1
2002
470
0.010
Why?
Mitochondria
1
2002
562
0.010
Why?
Anti-Bacterial Agents
1
2002
806
0.010
Why?
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